EA200501530A1 - Новые соединения бензотиадиазина, способ их получения и фармацевтические композиции, которые их содержат - Google Patents

Новые соединения бензотиадиазина, способ их получения и фармацевтические композиции, которые их содержат

Info

Publication number
EA200501530A1
EA200501530A1 EA200501530A EA200501530A EA200501530A1 EA 200501530 A1 EA200501530 A1 EA 200501530A1 EA 200501530 A EA200501530 A EA 200501530A EA 200501530 A EA200501530 A EA 200501530A EA 200501530 A1 EA200501530 A1 EA 200501530A1
Authority
EA
Eurasian Patent Office
Prior art keywords
benzothiadiazine
contain
production
pharmaceutical compositions
new compounds
Prior art date
Application number
EA200501530A
Other languages
English (en)
Other versions
EA011212B1 (ru
Inventor
Патрис Дезо
Алексис Корди
Пьер Лестаж
Original Assignee
Ле Лаборатуар Сервье
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ле Лаборатуар Сервье filed Critical Ле Лаборатуар Сервье
Publication of EA200501530A1 publication Critical patent/EA200501530A1/ru
Publication of EA011212B1 publication Critical patent/EA011212B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/15—Six-membered rings
    • C07D285/16—Thiadiazines; Hydrogenated thiadiazines
    • C07D285/18—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines
    • C07D285/20—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems
    • C07D285/22—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D285/24—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

Соединения формулы (I)в которой Rпредставляет собой алкил, замещенный одним или несколькими атомами галогена,Rпредставляет собой водород, галоген или ОН,Rпредставляет собой незамещенную или замещенную арильную группу,их изомеры, а также их аддитивные соли. Лекарственные средства.
EA200501530A 2004-11-03 2005-10-28 Новые соединения бензотиадиазина, способ их получения и фармацевтические композиции, которые их содержат EA011212B1 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0411690A FR2877338B1 (fr) 2004-11-03 2004-11-03 Nouveaux derives de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
EA200501530A1 true EA200501530A1 (ru) 2006-06-30
EA011212B1 EA011212B1 (ru) 2009-02-27

Family

ID=34950935

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200501530A EA011212B1 (ru) 2004-11-03 2005-10-28 Новые соединения бензотиадиазина, способ их получения и фармацевтические композиции, которые их содержат

Country Status (26)

Country Link
US (2) US7268130B2 (ru)
EP (1) EP1655030B1 (ru)
JP (1) JP2006151972A (ru)
KR (1) KR100818431B1 (ru)
CN (1) CN100396673C (ru)
AR (1) AR051149A1 (ru)
AT (1) ATE381338T1 (ru)
AU (1) AU2005229698A1 (ru)
BR (1) BRPI0504780A (ru)
CA (1) CA2524859A1 (ru)
DE (1) DE602005003907D1 (ru)
DK (1) DK1655030T3 (ru)
EA (1) EA011212B1 (ru)
ES (1) ES2298970T3 (ru)
FR (1) FR2877338B1 (ru)
GE (1) GEP20074256B (ru)
HR (1) HRP20080119T5 (ru)
MA (1) MA27917A1 (ru)
MX (1) MXPA05011820A (ru)
NO (1) NO20055167L (ru)
NZ (1) NZ543358A (ru)
PL (1) PL1655030T3 (ru)
PT (1) PT1655030E (ru)
SG (1) SG121999A1 (ru)
SI (1) SI1655030T1 (ru)
ZA (1) ZA200508911B (ru)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005280058B2 (en) * 2004-08-25 2010-09-02 Essentialis, Inc. Pharmaceutical formulations of potassium ATP channel openers and uses thereof
US7799777B2 (en) 2006-01-05 2010-09-21 Essentialis, Inc. Salts of potassium ATP channel openers and uses thereof
JP2010532383A (ja) * 2007-07-02 2010-10-07 エッセンシャリス，インク． カリウムａｔｐチャネル開口薬の塩およびその使用
US8124793B2 (en) * 2007-11-27 2012-02-28 Gail Marie Cronyn, legal representative Derivatives of ethylene methanedisulfonate as cancer chemotherapeutic agents
FR2943342B1 (fr) 2009-03-20 2011-03-04 Servier Lab Nouveaux derives de benzothiadiazepines,leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US20120100229A1 (en) * 2009-03-27 2012-04-26 Yale University Treatment and Prevention of White Matter Injury with KATP Channel Activators
FR2955106B1 (fr) * 2010-01-08 2011-12-23 Servier Lab Nouveaux derives de benzothiadiazines cyclopropylees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
KR101633632B1 (ko) 2015-09-30 2016-06-27 김동용 방사능 차폐재

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2722502B1 (fr) 1994-07-12 1996-08-23 Adir Nouveau derive de benzothiadiazine, son procede depreparation et les compositions pharmaceutiques qui le contiennent
AU4345297A (en) * 1996-09-17 1998-04-14 Regents Of The University Of California, The Benzothiadiazide derivatives and their use as allosteric up-modulators of the ampa receptor
EE200000468A (et) 1998-02-18 2002-04-15 Neurosearch A/S Ühendid, nende kasutamine ja farmatseutiline kompositsioon
FR2801587B1 (fr) * 1999-11-30 2002-01-11 Adir Nouveaux derives de benzothiadiazines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2833950B1 (fr) * 2001-12-21 2005-12-16 Servier Lab Nouveaux derives de benzothiazine et de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2833956B1 (fr) * 2001-12-21 2004-01-30 Servier Lab Nouveaux derives de benzothiazine et de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
MXPA05011820A (es) 2006-05-08
DK1655030T3 (da) 2008-04-28
SI1655030T1 (sl) 2008-04-30
GEP20074256B (en) 2007-12-10
FR2877338A1 (fr) 2006-05-05
NZ543358A (en) 2007-04-27
ES2298970T3 (es) 2008-05-16
US20070270415A1 (en) 2007-11-22
DE602005003907D1 (de) 2008-01-31
MA27917A1 (fr) 2006-06-01
ZA200508911B (en) 2006-07-26
PT1655030E (pt) 2008-02-08
HRP20080119T3 (en) 2008-04-30
EA011212B1 (ru) 2009-02-27
US20060094712A1 (en) 2006-05-04
SG121999A1 (en) 2006-05-26
PL1655030T3 (pl) 2008-03-31
ATE381338T1 (de) 2008-01-15
JP2006151972A (ja) 2006-06-15
AU2005229698A1 (en) 2006-05-18
FR2877338B1 (fr) 2007-01-26
KR100818431B1 (ko) 2008-04-01
CN1775767A (zh) 2006-05-24
AR051149A1 (es) 2006-12-20
BRPI0504780A (pt) 2006-06-27
EP1655030A1 (fr) 2006-05-10
CA2524859A1 (fr) 2006-05-03
NO20055167D0 (no) 2005-11-03
US7268130B2 (en) 2007-09-11
HRP20080119T5 (en) 2008-10-31
CN100396673C (zh) 2008-06-25
NO20055167L (no) 2006-05-04
KR20060052410A (ko) 2006-05-19
EP1655030B1 (fr) 2007-12-19

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU