EA200401404A1 - Комбинация агониста бета-2-адренорецепторов и аминосахара и их применение для лечения иммуномодуляторных расстройств - Google Patents

Комбинация агониста бета-2-адренорецепторов и аминосахара и их применение для лечения иммуномодуляторных расстройств

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Publication number
EA200401404A1
EA200401404A1 EA200401404A EA200401404A EA200401404A1 EA 200401404 A1 EA200401404 A1 EA 200401404A1 EA 200401404 A EA200401404 A EA 200401404A EA 200401404 A EA200401404 A EA 200401404A EA 200401404 A1 EA200401404 A1 EA 200401404A1
Authority
EA
Eurasian Patent Office
Prior art keywords
treatment
aminosachara
adrenocrator
bonet
agonists
Prior art date
Application number
EA200401404A
Other languages
English (en)
Other versions
EA007906B1 (ru
Inventor
Мортэн Слот Вэйднер
Original Assignee
Астион Девелопмент А/С
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Publication date
Application filed by Астион Девелопмент А/С filed Critical Астион Девелопмент А/С
Publication of EA200401404A1 publication Critical patent/EA200401404A1/ru
Publication of EA007906B1 publication Critical patent/EA007906B1/ru

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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/549—Sugars, nucleosides, nucleotides or nucleic acids
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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Abstract

Изобретение относится к комбинациям аминосахара и агониста β-2-адренорецепторов, например сальбутамола, для лечения заболеваний, связанных с гиперчувствительностью и воспалением, в частности, заболеваний гиперчувствительности кожи. Аминосахар предпочтительно представляет собой производное моносахарида.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200401404A 2002-04-19 2003-04-22 Комбинация агониста бета-2-адренорецепторов и аминосахара и их применение для лечения иммуномодуляторных расстройств EA007906B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37361502P 2002-04-19 2002-04-19
DKPA200200586 2002-04-19
PCT/DK2003/000263 WO2003097073A1 (en) 2002-04-19 2003-04-22 Combination of a beta-2 adrenoceptor agonists and an aminosugars and their use for the treatment immunomodulatory disorders

Publications (2)

Publication Number Publication Date
EA200401404A1 true EA200401404A1 (ru) 2005-04-28
EA007906B1 EA007906B1 (ru) 2007-02-27

Family

ID=49447268

Family Applications (1)

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EA200401404A EA007906B1 (ru) 2002-04-19 2003-04-22 Комбинация агониста бета-2-адренорецепторов и аминосахара и их применение для лечения иммуномодуляторных расстройств

Country Status (18)

Country Link
US (1) US20050130935A1 (ru)
EP (2) EP1496917B1 (ru)
JP (1) JP2005529151A (ru)
KR (1) KR20050007460A (ru)
CN (1) CN1646143A (ru)
AT (1) ATE311889T1 (ru)
AU (1) AU2003260279B2 (ru)
CA (1) CA2482746A1 (ru)
DE (1) DE60308915T2 (ru)
DK (1) DK1496917T3 (ru)
EA (1) EA007906B1 (ru)
ES (1) ES2254960T3 (ru)
HK (1) HK1073436A1 (ru)
NO (1) NO20045038L (ru)
NZ (1) NZ536447A (ru)
PL (1) PL373190A1 (ru)
SI (1) SI1496917T1 (ru)
WO (1) WO2003097073A1 (ru)

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US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
GB0604826D0 (en) * 2006-03-09 2006-04-19 Arakis Ltd The treatment of inflammatory disorders and pain
TW200817049A (en) * 2006-06-05 2008-04-16 Verus Pharmaceuticals Inc Epinephrine dosing regimens comprising buccal, lingual or sublingual and injectable dosage forms
US20070293581A1 (en) * 2006-06-05 2007-12-20 Malcolm Hill Methods for Buccal, Lingual or Sublingual Dosing Regimens of Epinephrine for the Treatment of Allergic Emergencies
GB0625270D0 (en) * 2006-12-19 2007-01-31 Univ Leicester Angiogenesis
CA2903133C (en) * 2007-05-31 2021-10-19 Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services National Institutes Of Health N-acetyl mannosamine or derivatives thereof for use in treating a kidney disorder in a mammal
GB0805535D0 (en) 2008-03-27 2008-04-30 Univ Leicester Scar prevention
US20110097401A1 (en) 2009-06-12 2011-04-28 Meritage Pharma, Inc. Methods for treating gastrointestinal disorders
US20120322884A1 (en) 2010-03-01 2012-12-20 University Of Manitoba Epinephrine nanoparticles, methods of fabrication thereof, and methods for use thereof for treatment of conditions responsive to epinephrine
JP2013523764A (ja) 2010-03-30 2013-06-17 アルジーノミクス インコーポレイテッド 体性感覚障害治療用の組成物と方法
US8716350B2 (en) 2010-03-30 2014-05-06 Algynomics Inc. Compositions and methods for the treatment of somatosensory disorders
CA2853084C (en) 2011-10-21 2022-04-26 Nova Southeastern University Epinephrine nanoparticles, methods of fabrication thereof, and methods for use thereof for treatment of conditions responsive to epinephrine
CA2876883C (en) 2012-06-15 2022-11-01 Nova Southeastern University Epinephrine nanoparticles, methods of fabrication thereof, and methods for use thereof for treatment of conditions responsive to epinephrine
GB2513297A (en) 2013-03-08 2014-10-29 Univ Leicester Methods
HUE055773T2 (hu) 2013-03-22 2021-12-28 Univ Nova Southeastern Epinefrin finom részecskék és módszerek azok alkalmazására az epinefrinre reagáló állapotok kezelésében
CN105601685B (zh) * 2016-01-08 2017-12-26 鲁东大学 含喹唑啉环壳寡糖衍生物及制备方法和生物活性
WO2018000098A1 (en) * 2016-06-30 2018-01-04 Cipher Pharmaceuticals Inc. Treatment of inflammatory myopathies

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Also Published As

Publication number Publication date
JP2005529151A (ja) 2005-09-29
KR20050007460A (ko) 2005-01-18
EP1496917A1 (en) 2005-01-19
DK1496917T3 (da) 2006-04-10
DE60308915T2 (de) 2006-12-21
EA007906B1 (ru) 2007-02-27
DE60308915D1 (de) 2006-11-16
AU2003260279B2 (en) 2008-01-24
AU2003260279A1 (en) 2003-12-02
EP1496917B1 (en) 2005-12-07
ES2254960T3 (es) 2006-06-16
SI1496917T1 (sl) 2006-06-30
CA2482746A1 (en) 2003-11-27
EP1642574A3 (en) 2008-11-12
CN1646143A (zh) 2005-07-27
PL373190A1 (en) 2005-08-22
NZ536447A (en) 2006-05-26
WO2003097073A1 (en) 2003-11-27
EP1642574A2 (en) 2006-04-05
ATE311889T1 (de) 2005-12-15
US20050130935A1 (en) 2005-06-16
NO20045038L (no) 2004-11-19
HK1073436A1 (en) 2005-10-07

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