EA200400338A1 - Средства лечения атеросклероза - Google Patents

Средства лечения атеросклероза

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Publication number
EA200400338A1
EA200400338A1 EA200400338A EA200400338A EA200400338A1 EA 200400338 A1 EA200400338 A1 EA 200400338A1 EA 200400338 A EA200400338 A EA 200400338A EA 200400338 A EA200400338 A EA 200400338A EA 200400338 A1 EA200400338 A1 EA 200400338A1
Authority
EA
Eurasian Patent Office
Prior art keywords
treatment
atherosclerosis
atherosclerotic disorders
lipid
identification
Prior art date
Application number
EA200400338A
Other languages
English (en)
Other versions
EA009661B1 (ru
Inventor
Иван Петяев
Original Assignee
Кембридж Тераностикс Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0120428A external-priority patent/GB0120428D0/en
Priority claimed from GB0202774A external-priority patent/GB0202774D0/en
Priority claimed from GB0204611A external-priority patent/GB0204611D0/en
Priority claimed from GB0216530A external-priority patent/GB0216530D0/en
Priority claimed from GB0216755A external-priority patent/GB0216755D0/en
Application filed by Кембридж Тераностикс Лтд. filed Critical Кембридж Тераностикс Лтд.
Publication of EA200400338A1 publication Critical patent/EA200400338A1/ru
Publication of EA009661B1 publication Critical patent/EA009661B1/ru

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56927—Chlamydia
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    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
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    • A61K31/13—Amines
    • A61K31/132—Amines having two or more amino groups, e.g. spermidine, putrescine
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    • A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
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    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
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    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
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    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
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    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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    • A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
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Abstract

Настоящее изобретение касается идентификации абзимов, окисляющих липиды, в качестве ключевого патогенного фактора при атеросклеротических расстройствах. Способы и средства снижения опосредованного абзимом окисления липида в сосудистой системе предложены в качестве терапевтических подходов для лечения атеросклеротических расстройств.Отчет о международном поиске был опубликован 2004.06.17.
EA200400338A 2001-08-22 2002-08-22 Способ лечения атеросклероза EA009661B1 (ru)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
GB0120428A GB0120428D0 (en) 2001-08-22 2001-08-22 Method of analysis
US32312701P 2001-09-18 2001-09-18
US35565502P 2002-02-06 2002-02-06
GB0202774A GB0202774D0 (en) 2002-02-06 2002-02-06 Methods and means
GB0204611A GB0204611D0 (en) 2002-02-27 2002-02-27 Methods of measurement
GB0216530A GB0216530D0 (en) 2002-07-16 2002-07-16 Methods and means
GB0216755A GB0216755D0 (en) 2002-07-18 2002-07-18 Methods and means
PCT/GB2002/003884 WO2003017992A2 (en) 2001-08-22 2002-08-22 Means for treatment of atherosclerosis

Publications (2)

Publication Number Publication Date
EA200400338A1 true EA200400338A1 (ru) 2004-12-30
EA009661B1 EA009661B1 (ru) 2008-02-28

Family

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Family Applications (1)

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EA200400338A EA009661B1 (ru) 2001-08-22 2002-08-22 Способ лечения атеросклероза

Country Status (9)

Country Link
EP (3) EP1456402A2 (ru)
JP (2) JP4307999B2 (ru)
AT (1) ATE436020T1 (ru)
AU (1) AU2002321526A1 (ru)
DE (2) DE60232992D1 (ru)
DK (2) DK1456670T3 (ru)
EA (1) EA009661B1 (ru)
ES (2) ES2328907T3 (ru)
WO (3) WO2003017992A2 (ru)

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WO2003017992A3 (en) 2004-06-17
AU2002321526A1 (en) 2003-03-10
EP1456670B8 (en) 2011-04-27
ES2329770T3 (es) 2009-12-01
EA009661B1 (ru) 2008-02-28
JP2005501258A (ja) 2005-01-13
JP4307999B2 (ja) 2009-08-05
WO2003019198A3 (en) 2004-03-04
WO2003019198A2 (en) 2003-03-06
EP1456402A2 (en) 2004-09-15
ATE436020T1 (de) 2009-07-15
WO2003019196A2 (en) 2003-03-06
EP1454140B1 (en) 2009-07-08
JP2005502665A (ja) 2005-01-27
EP1456670A2 (en) 2004-09-15
DK1454140T3 (da) 2009-11-16
EP1456670B1 (en) 2009-07-15
ES2328907T3 (es) 2009-11-19
DE60232913D1 (de) 2009-08-20
DK1456670T3 (da) 2009-11-16
EP1454140A2 (en) 2004-09-08
WO2003017992A2 (en) 2003-03-06
DE60232992D1 (de) 2009-08-27
WO2003019196A3 (en) 2004-03-04

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