EA200300246A1 - Ген и белок, ассоциированные с шизофренией - Google Patents

Ген и белок, ассоциированные с шизофренией

Info

Publication number
EA200300246A1
EA200300246A1 EA200300246A EA200300246A EA200300246A1 EA 200300246 A1 EA200300246 A1 EA 200300246A1 EA 200300246 A EA200300246 A EA 200300246A EA 200300246 A EA200300246 A EA 200300246A EA 200300246 A1 EA200300246 A1 EA 200300246A1
Authority
EA
Eurasian Patent Office
Prior art keywords
schizophrenia
genes
papap
proteins associated
gene
Prior art date
Application number
EA200300246A
Other languages
English (en)
Other versions
EA005921B1 (ru
Inventor
Бернар Биэн
Барбара Бур
Лиди Бугелере
Original Assignee
Женсет
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Женсет filed Critical Женсет
Publication of EA200300246A1 publication Critical patent/EA200300246A1/ru
Publication of EA005921B1 publication Critical patent/EA005921B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Neurology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

Настоящее изобретение относится к полинуклеотидам гена РАРАР, к полипептидам, кодируемым геном РАРАР, и к антителам, специфичным к таким полипептидам. Настоящее изобретение также относится к способам лечения или диагностики шизофрении, биполярного нарушения или родственного нарушения ЦНС. Настоящее изобретение также относится к взаимодействию РАРАР с геном g34872, который является кандидатом на ген шизофрении.Отчет о международном поиске был опубликован 2002.12.27.
EA200300246A 2000-08-07 2001-07-26 Ген и белок, ассоциированные с шизофренией EA005921B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22348200P 2000-08-07 2000-08-07
PCT/IB2001/001891 WO2002012279A2 (en) 2000-08-07 2001-07-26 Schizophrenia related gene and protein

Publications (2)

Publication Number Publication Date
EA200300246A1 true EA200300246A1 (ru) 2003-08-28
EA005921B1 EA005921B1 (ru) 2005-08-25

Family

ID=22836688

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200300246A EA005921B1 (ru) 2000-08-07 2001-07-26 Ген и белок, ассоциированные с шизофренией

Country Status (15)

Country Link
US (2) US7220581B2 (ru)
EP (1) EP1307560B1 (ru)
JP (1) JP2004516015A (ru)
KR (1) KR100781481B1 (ru)
CN (1) CN1468306A (ru)
AT (1) ATE340856T1 (ru)
AU (2) AU2001294088B2 (ru)
BR (1) BR0113099A (ru)
CA (1) CA2418779A1 (ru)
DE (1) DE60123434D1 (ru)
EA (1) EA005921B1 (ru)
IL (2) IL154298A0 (ru)
MX (1) MXPA03001150A (ru)
UA (1) UA79582C2 (ru)
WO (1) WO2002012279A2 (ru)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7442519B2 (en) 2002-06-25 2008-10-28 Serono Genetics Institute, S.A. KCNQ2-15 potassium channel
DE60316161T2 (de) * 2002-06-25 2008-06-19 Serono Genetics Institute S.A. Neue kcnq-polypeptide und deren verwendung bei der diagnose von geisteskrankheiten
US20040038385A1 (en) * 2002-08-26 2004-02-26 Langlois Richard G. System for autonomous monitoring of bioagents
CN100348722C (zh) * 2005-06-16 2007-11-14 吉林大学 精神分裂症关联基因
KR100642345B1 (ko) * 2005-11-02 2006-11-14 주식회사 대한콘설탄트 연약지반 침하방지를 위한 충격흡수형 철로
US20080075789A1 (en) * 2006-02-28 2008-03-27 The Regents Of The University Of California Genes differentially expressed in bipolar disorder and/or schizophrenia
US20140179613A1 (en) 2010-07-09 2014-06-26 The Regents Of The University Of Colorado, A Body Corporate COMPOSITIONS AND METHODS FOR CaMKII INHIBITORS AND USES THEREOF
US8816046B2 (en) * 2007-09-26 2014-08-26 The University Of Colorado, A Body Corporate Compositions and methods for CaMKII inhibitors and uses thereof
US8685926B2 (en) 2007-09-26 2014-04-01 The Regents Of The University Of Colorado, A Body Corporate Compositions and method for CaMKII inhibitors and uses thereof
US8892184B2 (en) 2010-10-18 2014-11-18 Siemens Medical Solutions Usa, Inc. Systems and methods for reducing interference in a dual modality imaging system
JP2015529685A (ja) 2012-09-17 2015-10-08 ザ・リサーチ・インスティテュート・アット・ネイションワイド・チルドレンズ・ホスピタルＴｈｅ Ｒｅｓｅａｒｃｈ Ｉｎｓｔｉｔｕｔｅ Ａｔｎａｔｉｏｎｗｉｄｅ Ｃｈｉｌｄｒｅｎ’Ｓ Ｈｏｓｐｉｔａｌ 筋萎縮性側索硬化症の処置のための組成物および方法
EP3065784A4 (en) * 2013-11-05 2017-05-10 The Research Institute at Nationwide Children's Hospital COMPOSITIONS AND METHODS FOR INHIBITING NF- kB AND SOD-1 TO TREAT AMYOTROPHIC LATERAL SCLEROSIS

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6222027B1 (en) * 1999-05-17 2001-04-24 Incyte Genomics, Inc. Molecules expressed in hippocampus
JP2004506442A (ja) 2000-08-25 2004-03-04 メルク　パテント　ゲゼルシャフト　ミット　ベシュレンクテル　ハフトング ＣａＭ−キナーゼＩＩ阻害剤の同定

Also Published As

Publication number Publication date
CN1468306A (zh) 2004-01-14
US7449543B2 (en) 2008-11-11
US20030148389A1 (en) 2003-08-07
AU2001294088B2 (en) 2006-09-07
KR100781481B1 (ko) 2007-12-03
IL154298A (en) 2007-12-03
JP2004516015A (ja) 2004-06-03
EP1307560B1 (en) 2006-09-27
UA79582C2 (en) 2007-07-10
EA005921B1 (ru) 2005-08-25
MXPA03001150A (es) 2005-04-11
EP1307560A2 (en) 2003-05-07
BR0113099A (pt) 2004-07-06
US7220581B2 (en) 2007-05-22
KR20030042449A (ko) 2003-05-28
CA2418779A1 (en) 2002-02-14
WO2002012279A3 (en) 2002-12-27
DE60123434D1 (de) 2006-11-09
US20080199883A1 (en) 2008-08-21
ATE340856T1 (de) 2006-10-15
AU9408801A (en) 2002-02-18
IL154298A0 (en) 2003-09-17
WO2002012279A2 (en) 2002-02-14

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Legal Events

Date Code Title Description
TC4A Change in name of a patent proprietor in a eurasian patent

Designated state(s): AM AZ BY KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU