EA200200535A1 - Применение треосульфана для подготовки пациентов перед трансплантацией костного мозга или трансплантацией стволовых клеток крови - Google Patents

Применение треосульфана для подготовки пациентов перед трансплантацией костного мозга или трансплантацией стволовых клеток крови

Info

Publication number
EA200200535A1
EA200200535A1 EA200200535A EA200200535A EA200200535A1 EA 200200535 A1 EA200200535 A1 EA 200200535A1 EA 200200535 A EA200200535 A EA 200200535A EA 200200535 A EA200200535 A EA 200200535A EA 200200535 A1 EA200200535 A1 EA 200200535A1
Authority
EA
Eurasian Patent Office
Prior art keywords
transplantation
treosulphane
application
stem cell
blood stem
Prior art date
Application number
EA200200535A
Other languages
English (en)
Other versions
EA004543B1 (ru
Inventor
Йоахим Баумгарт
Original Assignee
Медак Гезелльшафт Фюр Клинише Шпециальпрепарате Мбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Медак Гезелльшафт Фюр Клинише Шпециальпрепарате Мбх filed Critical Медак Гезелльшафт Фюр Клинише Шпециальпрепарате Мбх
Publication of EA200200535A1 publication Critical patent/EA200200535A1/ru
Publication of EA004543B1 publication Critical patent/EA004543B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Communicable Diseases (AREA)
  • Transplantation (AREA)
  • Oncology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Предлагаемое изобретение относится к применению треосульфана в качестве кондиционирующего агента перед аллогенной трансплантацией костного мозга или кроветворных стволовых клеток, причем треосульфан либо комбинируют с другими химиотерапевтическими или иммуноподавляющими средствами, либо вводят как единственное активное вещество.Отчет о международном поиске был опубликован 2002.01.24.
EA200200535A 1999-11-05 2000-11-03 Применение треосульфана для подготовки пациентов перед трансплантацией костного мозга или трансплантацией стволовых клеток крови EA004543B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19953517A DE19953517C1 (de) 1999-11-05 1999-11-05 Verwendung von Treosulfan zur Konditionierung von Patienten vor Knochemarktransplantation oder Blutstammzelltransplantation
PCT/EP2000/010871 WO2001032154A2 (de) 1999-11-05 2000-11-03 Verwendung von treosulfan zur konditionierung von patienten vor knochenmarktransplantation oder blutstammzelltransplantation

Publications (2)

Publication Number Publication Date
EA200200535A1 true EA200200535A1 (ru) 2002-10-31
EA004543B1 EA004543B1 (ru) 2004-06-24

Family

ID=7928187

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200200535A EA004543B1 (ru) 1999-11-05 2000-11-03 Применение треосульфана для подготовки пациентов перед трансплантацией костного мозга или трансплантацией стволовых клеток крови

Country Status (16)

Country Link
US (1) US7199162B1 (ru)
EP (1) EP1227808B1 (ru)
JP (1) JP4846151B2 (ru)
AT (1) ATE251455T1 (ru)
AU (1) AU777527B2 (ru)
BG (1) BG65845B1 (ru)
CA (1) CA2389896C (ru)
CZ (1) CZ299701B6 (ru)
DE (2) DE19953517C1 (ru)
EA (1) EA004543B1 (ru)
ES (1) ES2208435T3 (ru)
HU (2) HU227332B1 (ru)
NO (2) NO329616B1 (ru)
PL (1) PL212132B1 (ru)
UA (1) UA73961C2 (ru)
WO (1) WO2001032154A2 (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10237146A1 (de) * 2002-08-13 2004-03-04 Medac Gesellschaft für klinische Spezialpräparate mbH Verwendung von Treosulfan und Derivaten davon zur Behandlung der Multiplen Sklerose
JP7431815B2 (ja) * 2018-09-26 2024-02-15 メダック ゲゼルシャフト フィア クリニッシェ スペツィアルプレパラーテ ミット ベシュレンクタ ハフトゥンク トレオスルファンの結晶形
PL3856151T3 (pl) 2018-09-26 2024-02-19 Medac Gesellschaft für klinische Spezialpräparate mbH Liofilizat treosulfanu
WO2020064816A1 (en) 2018-09-26 2020-04-02 Medac Gesellschaft für klinische Spezialpräparate mbH Solution comprising treosulfan

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5376546A (en) * 1991-11-04 1994-12-27 Xoma Corporation Analogs of ribosome-inactivating proteins
DE4421391C1 (de) * 1994-06-18 1995-11-30 Gsf Forschungszentrum Umwelt Verwendung von Antikörpern gegen T-Zellen zur verlängerten Immunsuppression
WO2000045842A2 (en) * 1999-02-04 2000-08-10 The General Hospital Corporation Methods for human allografting

Also Published As

Publication number Publication date
NO329616B1 (no) 2010-11-22
WO2001032154A2 (de) 2001-05-10
UA73961C2 (ru) 2005-10-17
HUS1900041I1 (hu) 2019-10-28
WO2001032154A3 (de) 2002-01-24
AU1391801A (en) 2001-05-14
CA2389896C (en) 2007-04-10
JP4846151B2 (ja) 2011-12-28
US7199162B1 (en) 2007-04-03
CA2389896A1 (en) 2001-05-10
NO20022109L (no) 2002-07-01
BG106772A (bg) 2003-02-28
HUP0203277A2 (en) 2003-01-28
EA004543B1 (ru) 2004-06-24
JP2003513034A (ja) 2003-04-08
NO20022109D0 (no) 2002-05-02
BG65845B1 (bg) 2010-03-31
EP1227808B1 (de) 2003-10-08
CZ299701B6 (cs) 2008-10-22
PL356240A1 (en) 2004-06-28
ATE251455T1 (de) 2003-10-15
NO2019032I1 (no) 2019-07-23
PL212132B1 (pl) 2012-08-31
ES2208435T3 (es) 2004-06-16
HU227332B1 (en) 2011-03-28
AU777527B2 (en) 2004-10-21
CZ20021562A3 (cs) 2002-10-16
DE19953517C1 (de) 2001-08-09
EP1227808A2 (de) 2002-08-07
DE50004024D1 (de) 2003-11-13

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