EA200200535A1 - Применение треосульфана для подготовки пациентов перед трансплантацией костного мозга или трансплантацией стволовых клеток крови - Google Patents

Применение треосульфана для подготовки пациентов перед трансплантацией костного мозга или трансплантацией стволовых клеток крови

Info

Publication number
EA200200535A1
EA200200535A1 EA200200535A EA200200535A EA200200535A1 EA 200200535 A1 EA200200535 A1 EA 200200535A1 EA 200200535 A EA200200535 A EA 200200535A EA 200200535 A EA200200535 A EA 200200535A EA 200200535 A1 EA200200535 A1 EA 200200535A1
Authority
EA
Eurasian Patent Office
Prior art keywords
transplantation
treosulphane
application
stem cell
blood stem
Prior art date
Application number
EA200200535A
Other languages
English (en)
Other versions
EA004543B1 (ru
Inventor
Йоахим Баумгарт
Original Assignee
Медак Гезелльшафт Фюр Клинише Шпециальпрепарате Мбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Медак Гезелльшафт Фюр Клинише Шпециальпрепарате Мбх filed Critical Медак Гезелльшафт Фюр Клинише Шпециальпрепарате Мбх
Publication of EA200200535A1 publication Critical patent/EA200200535A1/ru
Publication of EA004543B1 publication Critical patent/EA004543B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Materials For Medical Uses (AREA)
  • Saccharide Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)

Abstract

Предлагаемое изобретение относится к применению треосульфана в качестве кондиционирующего агента перед аллогенной трансплантацией костного мозга или кроветворных стволовых клеток, причем треосульфан либо комбинируют с другими химиотерапевтическими или иммуноподавляющими средствами, либо вводят как единственное активное вещество.Отчет о международном поиске был опубликован 2002.01.24.
EA200200535A 1999-11-05 2000-11-03 Применение треосульфана для подготовки пациентов перед трансплантацией костного мозга или трансплантацией стволовых клеток крови EA004543B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19953517A DE19953517C1 (de) 1999-11-05 1999-11-05 Verwendung von Treosulfan zur Konditionierung von Patienten vor Knochemarktransplantation oder Blutstammzelltransplantation
PCT/EP2000/010871 WO2001032154A2 (de) 1999-11-05 2000-11-03 Verwendung von treosulfan zur konditionierung von patienten vor knochenmarktransplantation oder blutstammzelltransplantation

Publications (2)

Publication Number Publication Date
EA200200535A1 true EA200200535A1 (ru) 2002-10-31
EA004543B1 EA004543B1 (ru) 2004-06-24

Family

ID=7928187

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200200535A EA004543B1 (ru) 1999-11-05 2000-11-03 Применение треосульфана для подготовки пациентов перед трансплантацией костного мозга или трансплантацией стволовых клеток крови

Country Status (16)

Country Link
US (1) US7199162B1 (ru)
EP (1) EP1227808B1 (ru)
JP (1) JP4846151B2 (ru)
AT (1) ATE251455T1 (ru)
AU (1) AU777527B2 (ru)
BG (1) BG65845B1 (ru)
CA (1) CA2389896C (ru)
CZ (1) CZ299701B6 (ru)
DE (2) DE19953517C1 (ru)
EA (1) EA004543B1 (ru)
ES (1) ES2208435T3 (ru)
HU (2) HU227332B1 (ru)
NO (2) NO329616B1 (ru)
PL (1) PL212132B1 (ru)
UA (1) UA73961C2 (ru)
WO (1) WO2001032154A2 (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10237146A1 (de) 2002-08-13 2004-03-04 Medac Gesellschaft für klinische Spezialpräparate mbH Verwendung von Treosulfan und Derivaten davon zur Behandlung der Multiplen Sklerose
LT3856151T (lt) 2018-09-26 2023-11-27 Medac Gesellschaft für klinische Spezialpräparate mbH Treosulfano liofilizatas
CN112739421A (zh) 2018-09-26 2021-04-30 默德克学会特殊临床公司 曲奥舒凡的晶型
WO2020064816A1 (en) 2018-09-26 2020-04-02 Medac Gesellschaft für klinische Spezialpräparate mbH Solution comprising treosulfan

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5376546A (en) * 1991-11-04 1994-12-27 Xoma Corporation Analogs of ribosome-inactivating proteins
DE4421391C1 (de) * 1994-06-18 1995-11-30 Gsf Forschungszentrum Umwelt Verwendung von Antikörpern gegen T-Zellen zur verlängerten Immunsuppression
AU2980900A (en) * 1999-02-04 2000-08-25 General Hospital Corporation, The Methods for human allografting

Also Published As

Publication number Publication date
PL356240A1 (en) 2004-06-28
CZ20021562A3 (cs) 2002-10-16
AU777527B2 (en) 2004-10-21
CA2389896A1 (en) 2001-05-10
DE50004024D1 (de) 2003-11-13
ES2208435T3 (es) 2004-06-16
HUP0203277A2 (en) 2003-01-28
HU227332B1 (en) 2011-03-28
NO2019032I1 (no) 2019-07-23
EP1227808B1 (de) 2003-10-08
EP1227808A2 (de) 2002-08-07
ATE251455T1 (de) 2003-10-15
NO329616B1 (no) 2010-11-22
AU1391801A (en) 2001-05-14
EA004543B1 (ru) 2004-06-24
NO20022109L (no) 2002-07-01
WO2001032154A2 (de) 2001-05-10
BG106772A (bg) 2003-02-28
CZ299701B6 (cs) 2008-10-22
WO2001032154A3 (de) 2002-01-24
HUS1900041I1 (hu) 2019-10-28
DE19953517C1 (de) 2001-08-09
JP4846151B2 (ja) 2011-12-28
BG65845B1 (bg) 2010-03-31
UA73961C2 (ru) 2005-10-17
JP2003513034A (ja) 2003-04-08
CA2389896C (en) 2007-04-10
NO20022109D0 (no) 2002-05-02
US7199162B1 (en) 2007-04-03
PL212132B1 (pl) 2012-08-31

Similar Documents

Publication Publication Date Title
HUS1900041I1 (hu) Treoszulfán alkalmazása betegek csontvelõ- és vér õssejt-transzplantáció elõtti kondicionálására
NO2014016I2 (no) Dimetylfumarat
DE69941903D1 (de) Behandlung von patienten die eine knochenmarktransplantation oder eine transplantation peripherer blutstammzellen erhalten mit anti-cd20 antikörpern
FR2591485B1 (fr) Compositions stabilisees contenant l'activateur du plasminogene du tissu humain.
UA26855C2 (ru) Фармацевтическая композиция, регулирующая гематопоэз
DE69935153D1 (de) Benzamide als kaliumkanal-inhibitoren
BR9713338A (pt) Benzonaftiridinas como terapêuticos brÈnquicos.
ATE277628T1 (de) Behandlung von hematopoietischen zellen mit cxcr4 agonisten
ATE426402T1 (de) Medizinische zusammensetzungen enthaltend 2-amino-2-a2-(4-octylphenyl)ethylupropan-1,3-di l
EA200100855A1 (ru) Способы перфузии и композиции для перфузии
EA200200151A1 (ru) Сухая порошкообразная композиция
DE60033416D1 (de) Verwendung von hypoestoxiden als antiparasitäre mittel
ES2059986T3 (es) Una composicion para el tratamiento de la insuficiencia exocrina del pancreas, y el uso de dicha composicion.
EA200100366A1 (ru) Антагонист хемокинового рецептора и циклоспорин в комбинированной терапии
BR9809159A (pt) Composição farmacêutica contendo uscaridina ou seus análogos
GR3036481T3 (en) Medicament containing delta-aminolevulinic acid
RU2001134605A (ru) Применение протеина UK 114 для подавления отторжения трансплантатов органов
Hodge et al. Toxicity studies of sulfur hexafluoride (SF6) in pneumoperitoneum
JPS5696693A (en) Production of human standard enzyme sample from human placenta
ATE324898T1 (de) Behandlung von hiv infektionen
EA199900823A1 (ru) Ингибиторы протеазы вич
MX9700360A (es) Dinoclesido-5, 5 -pirofosfatos.
ES2058227T3 (es) Compuestos activos sobre el sistema cardiovascular.

Legal Events

Date Code Title Description
MK4A Patent expired

Designated state(s): AM AZ BY KZ KG MD TJ TM RU