EA200200414A1 - Композиция антагониста вазопрессина и способ ее получения - Google Patents

Композиция антагониста вазопрессина и способ ее получения

Info

Publication number
EA200200414A1
EA200200414A1 EA200200414A EA200200414A EA200200414A1 EA 200200414 A1 EA200200414 A1 EA 200200414A1 EA 200200414 A EA200200414 A EA 200200414A EA 200200414 A EA200200414 A EA 200200414A EA 200200414 A1 EA200200414 A1 EA 200200414A1
Authority
EA
Eurasian Patent Office
Prior art keywords
component
pharmaceutically acceptable
vazopressin
antagonist
obtaining
Prior art date
Application number
EA200200414A
Other languages
English (en)
Inventor
Джозеф Киювунг Йоон
Ричард Уилльям Сондерс
Махди Бакир Фози
Original Assignee
Американ Цианамид Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Американ Цианамид Компани filed Critical Американ Цианамид Компани
Publication of EA200200414A1 publication Critical patent/EA200200414A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Изобретение представляет новые композиции лекарственного средства на основе N-[4-(5H-пирроло[2,1-с][1,4]бензодиазепин-10(11Н)илкарбонил)-3-хлорфенил]-5-фтор-2-метилбензамида или его фармацевтически приемлемой соли и способы их получения, где композиции включают от около 1 до около 20% активного ингредиента, от около 1 до около 18% поверхностно-активного компонента, от около 50 до около 80% компонента, состоящего из одного или нескольких полиэтиленгликолей, от около 1 до около 20% компонента, состоящего из одного или нескольких сложных эфиров сахарозы и жирных кислот и/или поливинилпирролидона и, необязательно, один или несколько фармацевтически приемлемых консервантов или антиоксидантов.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200200414A 1999-09-27 2000-09-26 Композиция антагониста вазопрессина и способ ее получения EA200200414A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40577299A 1999-09-27 1999-09-27
PCT/US2000/026369 WO2001022945A1 (en) 1999-09-27 2000-09-26 Vasopressin antagonist formulation and process

Publications (1)

Publication Number Publication Date
EA200200414A1 true EA200200414A1 (ru) 2002-12-26

Family

ID=23605168

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200200414A EA200200414A1 (ru) 1999-09-27 2000-09-26 Композиция антагониста вазопрессина и способ ее получения

Country Status (18)

Country Link
EP (1) EP1216033A1 (ru)
JP (1) JP2003510269A (ru)
KR (1) KR20020039354A (ru)
CN (1) CN1391466A (ru)
AR (1) AR025780A1 (ru)
AU (1) AU7615000A (ru)
BR (1) BR0014351A (ru)
CA (1) CA2388474A1 (ru)
CZ (1) CZ20021083A3 (ru)
EA (1) EA200200414A1 (ru)
HK (1) HK1045109A1 (ru)
HU (1) HUP0202972A3 (ru)
IL (1) IL148541A0 (ru)
MX (1) MXPA02003189A (ru)
NO (1) NO20021475L (ru)
PL (1) PL354282A1 (ru)
WO (1) WO2001022945A1 (ru)
ZA (1) ZA200203312B (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030105144A1 (en) * 2001-04-17 2003-06-05 Ping Gao Stabilized oral pharmaceutical composition
AU2003211267A1 (en) * 2002-02-27 2003-09-09 Shionogi And Co., Ltd. Solid preparations with improved absorbability of hardly water-soluble drug
JP5873375B2 (ja) * 2012-04-03 2016-03-01 中日本カプセル 株式会社 ソフトカプセル及びソフトカプセルの製造方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5516774A (en) * 1993-07-29 1996-05-14 American Cyanamid Company Tricyclic diazepine vasopressin antagonists and oxytocin antagonists
EP1049459B1 (en) * 1998-01-20 2009-04-22 Applied Analytical Industries, Inc. Oral liquid compositions

Also Published As

Publication number Publication date
MXPA02003189A (es) 2002-09-30
KR20020039354A (ko) 2002-05-25
IL148541A0 (en) 2002-09-12
EP1216033A1 (en) 2002-06-26
CZ20021083A3 (cs) 2002-06-12
HUP0202972A2 (hu) 2002-12-28
AR025780A1 (es) 2002-12-11
HUP0202972A3 (en) 2003-07-28
ZA200203312B (en) 2003-12-31
WO2001022945A1 (en) 2001-04-05
CA2388474A1 (en) 2001-04-05
CN1391466A (zh) 2003-01-15
NO20021475D0 (no) 2002-03-25
HK1045109A1 (zh) 2002-11-15
NO20021475L (no) 2002-04-16
BR0014351A (pt) 2002-06-11
PL354282A1 (en) 2003-12-29
AU7615000A (en) 2001-04-30
JP2003510269A (ja) 2003-03-18

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