EA199900842A1 - Модуляторы функции рецепторов, принадлежащих к семейству рецепторов tnf/ngf - Google Patents

Модуляторы функции рецепторов, принадлежащих к семейству рецепторов tnf/ngf

Info

Publication number
EA199900842A1
EA199900842A1 EA199900842A EA199900842A EA199900842A1 EA 199900842 A1 EA199900842 A1 EA 199900842A1 EA 199900842 A EA199900842 A EA 199900842A EA 199900842 A EA199900842 A EA 199900842A EA 199900842 A1 EA199900842 A1 EA 199900842A1
Authority
EA
Eurasian Patent Office
Prior art keywords
receptor
tnf
modulators
functions belonging
ngf
Prior art date
Application number
EA199900842A
Other languages
English (en)
Other versions
EA006874B1 (ru
Inventor
Дэвид Валлах
Андрей Коваленко
Original Assignee
Йеда Рисерч Энд Дивелопмент Ко., Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Йеда Рисерч Энд Дивелопмент Ко., Лтд. filed Critical Йеда Рисерч Энд Дивелопмент Ко., Лтд.
Publication of EA199900842A1 publication Critical patent/EA199900842A1/ru
Publication of EA006874B1 publication Critical patent/EA006874B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

Описаны белки, которые способны модулировать/опосредовать функцию RIP, а также их получение и использование.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA199900842A 1997-03-19 1998-03-19 Полипептид, обладающий активностью rap [белка, ассоциированного с rip (взаимодействующим с рецептором белком)], кодирующая его последовательность днк и способы их получения и использования EA006874B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL12048597A IL120485A0 (en) 1997-03-19 1997-03-19 Modulators of the function of receptors of the TNF/NGF receptor family and other proteins
PCT/IL1998/000125 WO1998041624A1 (en) 1997-03-19 1998-03-19 Modulators of the function of receptors of the tnf/ngf receptor family

Publications (2)

Publication Number Publication Date
EA199900842A1 true EA199900842A1 (ru) 2000-04-24
EA006874B1 EA006874B1 (ru) 2006-04-28

Family

ID=11069938

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199900842A EA006874B1 (ru) 1997-03-19 1998-03-19 Полипептид, обладающий активностью rap [белка, ассоциированного с rip (взаимодействующим с рецептором белком)], кодирующая его последовательность днк и способы их получения и использования

Country Status (14)

Country Link
US (3) US7083788B2 (ru)
EP (1) EP0972033A1 (ru)
JP (1) JP2001519656A (ru)
KR (1) KR20000075718A (ru)
CN (1) CN1189564C (ru)
AU (1) AU747005B2 (ru)
BR (1) BR9808915A (ru)
CA (1) CA2281738A1 (ru)
EA (1) EA006874B1 (ru)
HK (1) HK1025127A1 (ru)
IL (3) IL120485A0 (ru)
NO (1) NO994524L (ru)
UA (1) UA72186C2 (ru)
WO (1) WO1998041624A1 (ru)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL120485A0 (en) * 1997-03-19 1997-07-13 Yeda Res & Dev Modulators of the function of receptors of the TNF/NGF receptor family and other proteins
US6548633B1 (en) 1998-12-22 2003-04-15 Genset, S.A. Complementary DNA's encoding proteins with signal peptides
AU5730300A (en) * 1999-06-11 2001-01-02 Burnham Institute, The Nucleic acid encoding proteins involved in protein degradation, products and methods related thereto
US7087386B2 (en) 1999-06-11 2006-08-08 The Burnham Institute Nucleic acid encoding proteins involved in protein degradation, products and methods related thereto
US6638734B1 (en) 1999-06-11 2003-10-28 The Burnham Institute Nucleic acid encoding proteins involved in protein degradation, products and methods related thereto
US7504253B2 (en) 1999-06-11 2009-03-17 The Burnham Institute For Medical Research Nucleic acid encoding proteins involved in protein degradation, products and methods related thereof
CN1311254A (zh) * 2000-03-02 2001-09-05 上海博德基因开发有限公司 一种新的多肽——人含细胞色素c结构域的 tnfr/nger蛋白13和编码这种多肽的多核苷酸
US7076602B2 (en) * 2001-11-05 2006-07-11 Hywire Ltd. Multi-dimensional associative search engine having an external memory
US7388079B2 (en) * 2002-11-27 2008-06-17 The Regents Of The University Of California Delivery of pharmaceutical agents via the human insulin receptor
US20090188721A1 (en) * 2008-01-30 2009-07-30 Smith Kevin W Membrane method of making drilling fluids containing microbubbles
IL189408A0 (en) 2008-02-10 2009-02-11 Yeda Res & Dev Siva3, its preparation and pharmaceutical compositions containing it

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5698443A (en) 1995-06-27 1997-12-16 Calydon, Inc. Tissue specific viral vectors
PT813419E (pt) * 1995-02-22 2005-09-30 Yeda Res & Dev Moduladores de proteinas reguladoras
IL120485A0 (en) * 1997-03-19 1997-07-13 Yeda Res & Dev Modulators of the function of receptors of the TNF/NGF receptor family and other proteins
US6573094B1 (en) * 1997-10-16 2003-06-03 Baylor College Of Medicine F-box genes and proteins

Also Published As

Publication number Publication date
CN1189564C (zh) 2005-02-16
NO994524L (no) 1999-11-11
CN1250479A (zh) 2000-04-12
US20030039646A1 (en) 2003-02-27
IL120485A0 (en) 1997-07-13
AU747005B2 (en) 2002-05-09
JP2001519656A (ja) 2001-10-23
US20020058024A1 (en) 2002-05-16
CA2281738A1 (en) 1998-09-24
EP0972033A1 (en) 2000-01-19
US20080159986A1 (en) 2008-07-03
NO994524D0 (no) 1999-09-17
UA72186C2 (en) 2005-02-15
US7083788B2 (en) 2006-08-01
HK1025127A1 (en) 2000-11-03
IL131929A0 (en) 2001-03-19
AU6634798A (en) 1998-10-12
BR9808915A (pt) 2000-08-01
WO1998041624A1 (en) 1998-09-24
IL131929A (en) 2008-03-20
US7189535B2 (en) 2007-03-13
KR20000075718A (ko) 2000-12-26
EA006874B1 (ru) 2006-04-28

Similar Documents

Publication Publication Date Title
EA199900381A1 (ru) Арил(тио)эфиры галогенпиримидина в качестве пестицидов
EA200400241A1 (ru) Направленные к мишени мультимерные контрастные вещества, основанные на пептидах
EA200000216A1 (ru) Белки, связывающие интерлейкин-18, их получение и применение
BR0013231A (pt) Complexos citocina-anticorpo múltiplos
EA199900598A1 (ru) Производные 1-арил- и пиридилпиразола с пестицидными свойствами
ES2139329T3 (es) Nuevas variantes de la proteina fluorescente verde, gfp.
EA200100012A1 (ru) Мостиковые инденопирролокарбазолы
EA199800733A1 (ru) Антагонисты рецептора il-8
EA200000251A1 (ru) Производные резорцинола
EA200000565A1 (ru) Цитокин-подобный полипептид-10 млекопитающих
EA199700359A1 (ru) Пептиды и соединения, связывающиеся с тромбопоэтиновым рецептором
DE69434520D1 (de) Biotinylierung von proteinen
EA199700421A1 (ru) Искуственная разделительная мембрана
EA200001053A1 (ru) Смесь веществ для местного применения
EA199800946A1 (ru) Концентрированный препарат антител
FI972390A (fi) Sytokiini nimeltä Lerk-7
ATE332368T1 (de) Selektion von proteinen mittels rns-protein fusionen
EA199900842A1 (ru) Модуляторы функции рецепторов, принадлежащих к семейству рецепторов tnf/ngf
EA199900187A1 (ru) Лиганд, родственный фактору некроза опухоли
ATE186738T1 (de) Kohlenhydratmodifizierte cytostatika
EA199901024A1 (ru) Фармацевтическая антивирусная композиция, содержащая глицирризиновую кислоту и, по меньшей мере, один белок, обладающий антивирусной активностью
EA200200974A1 (ru) Моноклональные антитела к рецептору лпнп человека, их получение и применение
EA199900235A1 (ru) Аморфные бензотиофены, способы получения и способы применения
EA199901117A1 (ru) Модуляторы путей внутриклеточного воспаления, клеточной гибели и клеточного выживания
DK0939769T3 (da) Vertebrat-Smoothened-proteiner

Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU