EA199900530A1 - Гидрат n-(4-ацетил-1-пиперазинил)-4-фторбензамида - Google Patents

Гидрат n-(4-ацетил-1-пиперазинил)-4-фторбензамида

Info

Publication number
EA199900530A1
EA199900530A1 EA199900530A EA199900530A EA199900530A1 EA 199900530 A1 EA199900530 A1 EA 199900530A1 EA 199900530 A EA199900530 A EA 199900530A EA 199900530 A EA199900530 A EA 199900530A EA 199900530 A1 EA199900530 A1 EA 199900530A1
Authority
EA
Eurasian Patent Office
Prior art keywords
acetyl
fluorobenzamide
hydrate
piperasinyl
piperazinyl
Prior art date
Application number
EA199900530A
Other languages
English (en)
Other versions
EA001715B1 (ru
Inventor
Сатоси Китамура
Хисаси Мимура
Хироси Ямасаки
Юкихиза Баба
Original Assignee
Фудзисава Фармасьютикал Ко., Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Фудзисава Фармасьютикал Ко., Лтд. filed Critical Фудзисава Фармасьютикал Ко., Лтд.
Publication of EA199900530A1 publication Critical patent/EA199900530A1/ru
Publication of EA001715B1 publication Critical patent/EA001715B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/28—Nitrogen atoms
    • C07D295/32—Nitrogen atoms acylated with carboxylic or carbonic acids, or their nitrogen or sulfur analogues
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Настоящее изобретение своей целью имеет предоставление N-(4-ацетил-1-пиперазинил)-4-фторбензамида в форме, легкой и удобной в обращении и стабильной в отношении тестирования в стрессовых условиях. Гидрат N-(4-ацетил-1-пиперазинил)-4-фторбензамида легок и удобен в обращении в условиях обычной влажности в помещении и стабилен в отношении условий ускоренных тестов на воздействие нагревания, влажности и света.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA199900530A 1996-12-12 1997-12-05 Гидрат n-(4-ацетил-1-пиперазинил)-4-фторбензамида EA001715B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP33178496 1996-12-12
PCT/JP1997/004451 WO1998025914A1 (en) 1996-12-12 1997-12-05 N-(4-acetyl-1-piperazinyl)-4-fluorobenzamide hydrate

Publications (2)

Publication Number Publication Date
EA199900530A1 true EA199900530A1 (ru) 1999-12-29
EA001715B1 EA001715B1 (ru) 2001-08-27

Family

ID=18247607

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199900530A EA001715B1 (ru) 1996-12-12 1997-12-05 Гидрат n-(4-ацетил-1-пиперазинил)-4-фторбензамида

Country Status (20)

Country Link
US (1) US6147079A (ru)
EP (1) EP0944612B1 (ru)
JP (1) JP3254683B2 (ru)
KR (1) KR20000057342A (ru)
CN (1) CN1073104C (ru)
AT (1) ATE205198T1 (ru)
AU (1) AU722095B2 (ru)
CA (1) CA2274682A1 (ru)
DE (1) DE69706562T2 (ru)
DK (1) DK0944612T3 (ru)
EA (1) EA001715B1 (ru)
ES (1) ES2160371T3 (ru)
GR (1) GR3036542T3 (ru)
HK (1) HK1024482A1 (ru)
HU (1) HUP0002975A3 (ru)
IL (1) IL130273A (ru)
PT (1) PT944612E (ru)
TW (1) TW422844B (ru)
WO (1) WO1998025914A1 (ru)
ZA (1) ZA9710872B (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9812736A (pt) * 1997-10-09 2000-08-22 Fujisawa Pharmaceutical Co Novo processo para produzir derivados de aminopiperazina
AUPP818099A0 (en) 1999-01-14 1999-02-11 Fujisawa Pharmaceutical Co., Ltd. New n-containing heterocyclic compounds
US6344358B1 (en) * 1999-05-28 2002-02-05 Fujisawa Pharmaceutical Co., Ltd. Agent for expression of long-term potentiation of synaptic transmission comprising compound having brain somatostatin activation property
GB0021885D0 (en) * 2000-09-06 2000-10-18 Fujisawa Pharmaceutical Co New use
WO2002034735A1 (fr) * 2000-10-23 2002-05-02 Fujisawa Pharmaceutical Co., Ltd. Procede de preparation d'un solvate et solvate
WO2002045715A1 (fr) * 2000-12-07 2002-06-13 Fujisawa Pharmaceutical Co., Ltd. Nootropes
EP1498126A1 (en) * 2002-04-10 2005-01-19 Fujisawa Pharmaceutical Co., Ltd. Neurotrophic factor production accelerator

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5250528A (en) * 1989-08-02 1993-10-05 Fujisawa Pharmaceutical Co., Ltd. New aminopiperazine derivatives
GB8917687D0 (en) * 1989-08-02 1989-09-20 Fujisawa Pharmaceutical Co Aminopiperazine derivatives,processes for preparation thereof and pharmaceutical composition comprising the same

Also Published As

Publication number Publication date
DE69706562D1 (de) 2001-10-11
CN1073104C (zh) 2001-10-17
AU722095B2 (en) 2000-07-20
JP3254683B2 (ja) 2002-02-12
TW422844B (en) 2001-02-21
JP2000514460A (ja) 2000-10-31
ATE205198T1 (de) 2001-09-15
EA001715B1 (ru) 2001-08-27
KR20000057342A (ko) 2000-09-15
GR3036542T3 (en) 2001-12-31
ES2160371T3 (es) 2001-11-01
HUP0002975A2 (hu) 2001-12-28
EP0944612A1 (en) 1999-09-29
IL130273A0 (en) 2000-06-01
ZA9710872B (en) 1998-06-15
CN1245495A (zh) 2000-02-23
EP0944612B1 (en) 2001-09-05
HUP0002975A3 (en) 2002-01-28
DE69706562T2 (de) 2002-05-29
WO1998025914A1 (en) 1998-06-18
IL130273A (en) 2003-05-29
HK1024482A1 (en) 2000-10-13
PT944612E (pt) 2002-01-30
AU5136898A (en) 1998-07-03
DK0944612T3 (da) 2001-11-19
US6147079A (en) 2000-11-14
CA2274682A1 (en) 1998-06-18

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU