IL130273A - N-(4-acetyl-1-piperazinyl)-4-fluorobenzamide hydrate, pharmaceutical compositions containing the same and the use thereof for the manufacture of medicaments - Google Patents

N-(4-acetyl-1-piperazinyl)-4-fluorobenzamide hydrate, pharmaceutical compositions containing the same and the use thereof for the manufacture of medicaments

Info

Publication number
IL130273A
IL130273A IL13027397A IL13027397A IL130273A IL 130273 A IL130273 A IL 130273A IL 13027397 A IL13027397 A IL 13027397A IL 13027397 A IL13027397 A IL 13027397A IL 130273 A IL130273 A IL 130273A
Authority
IL
Israel
Prior art keywords
piperazinyl
acetyl
pct
medicaments
manufacture
Prior art date
Application number
IL13027397A
Other languages
English (en)
Other versions
IL130273A0 (en
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of IL130273A0 publication Critical patent/IL130273A0/xx
Publication of IL130273A publication Critical patent/IL130273A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/28—Nitrogen atoms
    • C07D295/32—Nitrogen atoms acylated with carboxylic or carbonic acids, or their nitrogen or sulfur analogues
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicinal Preparation (AREA)
IL13027397A 1996-12-12 1997-12-05 N-(4-acetyl-1-piperazinyl)-4-fluorobenzamide hydrate, pharmaceutical compositions containing the same and the use thereof for the manufacture of medicaments IL130273A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP33178496 1996-12-12
PCT/JP1997/004451 WO1998025914A1 (en) 1996-12-12 1997-12-05 N-(4-acetyl-1-piperazinyl)-4-fluorobenzamide hydrate

Publications (2)

Publication Number Publication Date
IL130273A0 IL130273A0 (en) 2000-06-01
IL130273A true IL130273A (en) 2003-05-29

Family

ID=18247607

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13027397A IL130273A (en) 1996-12-12 1997-12-05 N-(4-acetyl-1-piperazinyl)-4-fluorobenzamide hydrate, pharmaceutical compositions containing the same and the use thereof for the manufacture of medicaments

Country Status (20)

Country Link
US (1) US6147079A (xx)
EP (1) EP0944612B1 (xx)
JP (1) JP3254683B2 (xx)
KR (1) KR20000057342A (xx)
CN (1) CN1073104C (xx)
AT (1) ATE205198T1 (xx)
AU (1) AU722095B2 (xx)
CA (1) CA2274682A1 (xx)
DE (1) DE69706562T2 (xx)
DK (1) DK0944612T3 (xx)
EA (1) EA001715B1 (xx)
ES (1) ES2160371T3 (xx)
GR (1) GR3036542T3 (xx)
HK (1) HK1024482A1 (xx)
HU (1) HUP0002975A3 (xx)
IL (1) IL130273A (xx)
PT (1) PT944612E (xx)
TW (1) TW422844B (xx)
WO (1) WO1998025914A1 (xx)
ZA (1) ZA9710872B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6355800B1 (en) * 1997-10-09 2002-03-12 Fujisawa Pharmaceutical Co., Ltd. Process for producing aminopiperazine derivatives
AUPP818099A0 (en) * 1999-01-14 1999-02-11 Fujisawa Pharmaceutical Co., Ltd. New n-containing heterocyclic compounds
US6344358B1 (en) * 1999-05-28 2002-02-05 Fujisawa Pharmaceutical Co., Ltd. Agent for expression of long-term potentiation of synaptic transmission comprising compound having brain somatostatin activation property
GB0021885D0 (en) * 2000-09-06 2000-10-18 Fujisawa Pharmaceutical Co New use
WO2002034735A1 (fr) * 2000-10-23 2002-05-02 Fujisawa Pharmaceutical Co., Ltd. Procede de preparation d'un solvate et solvate
CA2431181A1 (en) * 2000-12-07 2002-06-13 Nobuya Matsuoka Nootropic effect enhancer
US20060069104A1 (en) * 2002-04-10 2006-03-30 Toshio Matsuda Neurotrophic factor production accelerator

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8917687D0 (en) * 1989-08-02 1989-09-20 Fujisawa Pharmaceutical Co Aminopiperazine derivatives,processes for preparation thereof and pharmaceutical composition comprising the same
US5250528A (en) * 1989-08-02 1993-10-05 Fujisawa Pharmaceutical Co., Ltd. New aminopiperazine derivatives

Also Published As

Publication number Publication date
EP0944612B1 (en) 2001-09-05
JP3254683B2 (ja) 2002-02-12
AU722095B2 (en) 2000-07-20
CN1073104C (zh) 2001-10-17
EA199900530A1 (ru) 1999-12-29
KR20000057342A (ko) 2000-09-15
PT944612E (pt) 2002-01-30
WO1998025914A1 (en) 1998-06-18
DE69706562D1 (de) 2001-10-11
ATE205198T1 (de) 2001-09-15
AU5136898A (en) 1998-07-03
CA2274682A1 (en) 1998-06-18
EA001715B1 (ru) 2001-08-27
HUP0002975A2 (hu) 2001-12-28
ES2160371T3 (es) 2001-11-01
HK1024482A1 (en) 2000-10-13
IL130273A0 (en) 2000-06-01
HUP0002975A3 (en) 2002-01-28
JP2000514460A (ja) 2000-10-31
EP0944612A1 (en) 1999-09-29
DE69706562T2 (de) 2002-05-29
CN1245495A (zh) 2000-02-23
GR3036542T3 (en) 2001-12-31
ZA9710872B (en) 1998-06-15
US6147079A (en) 2000-11-14
TW422844B (en) 2001-02-21
DK0944612T3 (da) 2001-11-19

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
HC Change of name of proprietor(s)
MM9K Patent not in force due to non-payment of renewal fees