EA199800920A1 - Производные фенилэтаноламинотетралинкарбоксамида - Google Patents
Производные фенилэтаноламинотетралинкарбоксамидаInfo
- Publication number
- EA199800920A1 EA199800920A1 EA199800920A EA199800920A EA199800920A1 EA 199800920 A1 EA199800920 A1 EA 199800920A1 EA 199800920 A EA199800920 A EA 199800920A EA 199800920 A EA199800920 A EA 199800920A EA 199800920 A1 EA199800920 A1 EA 199800920A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- carbon atom
- configuration
- amino group
- agent
- marked
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/04—Drugs for disorders of the urinary system for urolithiasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Pulmonology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Настоящее изобретение относится к производным фенилэтаноламинотетралинкарбоксамида, представленным общей формулой:(в которой А представляет низшую алкиленовую группу; В представляет аминогруппу, ди(низший алкил)аминогруппу или 3-7-членную алициклическую аминогруппу, которая может содержать атом кислорода в кольце; атом углерода, отмеченный звездочкой (*), представляет атом углерода в (R) конфигурации, (S) конфигурации или их смесь; и атом углерода, отмеченный (S), является атомом углерода в (S) конфигурации), и к их фармацевтически приемлемой соли, которые оказывают избирательное стимулирующее действие на β-адренергические рецепторы при гораздо меньшей нагрузке на сердце, такой как тахикардия, и являются эффективными агентами, предупреждающими угрозу выкидыша и преждевременные роды, бронходиляторами, болеутоляющими средствами и средствами, стимулирующими выведение камней при мочекаменной болезни.Международная заявка была опубликована вместе с отчетом о международном поиске.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12622596 | 1996-04-12 | ||
PCT/JP1997/001159 WO1997038970A1 (fr) | 1996-04-12 | 1997-04-04 | Derives de phenylethanolaminotetralincarboxamide |
Publications (2)
Publication Number | Publication Date |
---|---|
EA199800920A1 true EA199800920A1 (ru) | 1999-04-29 |
EA001108B1 EA001108B1 (ru) | 2000-10-30 |
Family
ID=14929861
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA199800920A EA001108B1 (ru) | 1996-04-12 | 1997-04-04 | Производные фенилэтаноламинотетралинкарбоксамида |
Country Status (19)
Country | Link |
---|---|
US (1) | US6046192A (ru) |
EP (1) | EP0893432B1 (ru) |
JP (1) | JP4044615B2 (ru) |
CN (1) | CN1100033C (ru) |
AT (1) | ATE344792T1 (ru) |
AU (1) | AU726686B2 (ru) |
BR (1) | BR9708642A (ru) |
CZ (1) | CZ327598A3 (ru) |
DE (1) | DE69736924T2 (ru) |
EA (1) | EA001108B1 (ru) |
ES (1) | ES2275284T3 (ru) |
ID (1) | ID19038A (ru) |
MY (1) | MY118678A (ru) |
NO (1) | NO984699L (ru) |
NZ (1) | NZ332212A (ru) |
PL (1) | PL188158B1 (ru) |
SG (1) | SG55296A1 (ru) |
TW (1) | TW448143B (ru) |
WO (1) | WO1997038970A1 (ru) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1276911C (zh) * | 2001-09-30 | 2006-09-27 | 沈阳药科大学 | 具有β2-受体兴奋作用的新型苯乙醇胺类化合物及其制法 |
MX2009008994A (es) | 2007-02-21 | 2009-09-03 | Kissei Pharmaceutical | Composicion farmaceutica para la prevencion o tratamiento de enfermedades asociadas con la reduccion de lagrimas. |
EP2098511A1 (en) | 2008-03-07 | 2009-09-09 | Solvias AG | Process for preparing compounds containing a hydronaphtalene structure with an unsymmetrically substituted benzene ring |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9107827D0 (en) * | 1991-04-12 | 1991-05-29 | Fujisawa Pharmaceutical Co | New ethanolamine derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same |
WO1993018007A1 (en) * | 1992-03-13 | 1993-09-16 | Tokyo Tanabe Company Limited | Novel carbostyril derivative |
AU8562098A (en) * | 1997-08-19 | 1999-03-08 | Kissei Pharmaceutical Co. Ltd. | Phenylethanolaminotetralin derivatives and bronchodilators |
-
1997
- 1997-04-01 SG SG1997001031A patent/SG55296A1/en unknown
- 1997-04-03 MY MYPI97001450A patent/MY118678A/en unknown
- 1997-04-04 EP EP97914598A patent/EP0893432B1/en not_active Expired - Lifetime
- 1997-04-04 CZ CZ983275A patent/CZ327598A3/cs unknown
- 1997-04-04 US US09/155,478 patent/US6046192A/en not_active Expired - Fee Related
- 1997-04-04 PL PL97329315A patent/PL188158B1/pl not_active IP Right Cessation
- 1997-04-04 NZ NZ332212A patent/NZ332212A/xx unknown
- 1997-04-04 AU AU21783/97A patent/AU726686B2/en not_active Ceased
- 1997-04-04 JP JP53693397A patent/JP4044615B2/ja not_active Expired - Fee Related
- 1997-04-04 WO PCT/JP1997/001159 patent/WO1997038970A1/ja active IP Right Grant
- 1997-04-04 EA EA199800920A patent/EA001108B1/ru not_active IP Right Cessation
- 1997-04-04 DE DE69736924T patent/DE69736924T2/de not_active Expired - Fee Related
- 1997-04-04 AT AT97914598T patent/ATE344792T1/de not_active IP Right Cessation
- 1997-04-04 ES ES97914598T patent/ES2275284T3/es not_active Expired - Lifetime
- 1997-04-04 CN CN97194877A patent/CN1100033C/zh not_active Expired - Fee Related
- 1997-04-04 BR BR9708642A patent/BR9708642A/pt not_active Application Discontinuation
- 1997-04-10 TW TW086104755A patent/TW448143B/zh not_active IP Right Cessation
- 1997-04-11 ID IDP971211A patent/ID19038A/id unknown
-
1998
- 1998-10-08 NO NO984699A patent/NO984699L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP0893432A1 (en) | 1999-01-27 |
US6046192A (en) | 2000-04-04 |
MY118678A (en) | 2005-01-31 |
SG55296A1 (en) | 1998-12-21 |
WO1997038970A1 (fr) | 1997-10-23 |
NZ332212A (en) | 1999-08-30 |
AU2178397A (en) | 1997-11-07 |
AU726686B2 (en) | 2000-11-16 |
EA001108B1 (ru) | 2000-10-30 |
NO984699L (no) | 1998-12-11 |
CN1219926A (zh) | 1999-06-16 |
DE69736924T2 (de) | 2007-03-01 |
ES2275284T3 (es) | 2007-06-01 |
NO984699D0 (no) | 1998-10-08 |
BR9708642A (pt) | 1999-08-03 |
EP0893432A4 (en) | 2002-01-02 |
TW448143B (en) | 2001-08-01 |
CN1100033C (zh) | 2003-01-29 |
ATE344792T1 (de) | 2006-11-15 |
DE69736924D1 (en) | 2006-12-21 |
EP0893432B1 (en) | 2006-11-08 |
PL329315A1 (en) | 1999-03-15 |
CZ327598A3 (cs) | 1999-01-13 |
PL188158B1 (pl) | 2004-12-31 |
ID19038A (id) | 1998-06-04 |
JP4044615B2 (ja) | 2008-02-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM |
|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): RU |