EA035966B1 - Применение фармацевтической композиции для местного применения для лечения расстройств лакримальной системы и переднего отрезка глаза - Google Patents

Применение фармацевтической композиции для местного применения для лечения расстройств лакримальной системы и переднего отрезка глаза Download PDF

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Publication number
EA035966B1
EA035966B1 EA201591653A EA201591653A EA035966B1 EA 035966 B1 EA035966 B1 EA 035966B1 EA 201591653 A EA201591653 A EA 201591653A EA 201591653 A EA201591653 A EA 201591653A EA 035966 B1 EA035966 B1 EA 035966B1
Authority
EA
Eurasian Patent Office
Prior art keywords
corneal
eye
dipyridamole
solution
anterior segment
Prior art date
Application number
EA201591653A
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English (en)
Russian (ru)
Other versions
EA201591653A1 (ru
Inventor
Моше Рогосницки
Original Assignee
О.Д. Окуляр Дискавери, Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by О.Д. Окуляр Дискавери, Лтд. filed Critical О.Д. Окуляр Дискавери, Лтд.
Publication of EA201591653A1 publication Critical patent/EA201591653A1/ru
Publication of EA035966B1 publication Critical patent/EA035966B1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/133—Amines having hydroxy groups, e.g. sphingosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
EA201591653A 2013-03-12 2014-03-11 Применение фармацевтической композиции для местного применения для лечения расстройств лакримальной системы и переднего отрезка глаза EA035966B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL225179A IL225179A (en) 2013-03-12 2013-03-12 Compounds for use in ocular disorders using dipyridamole
PCT/IB2014/059645 WO2014141079A1 (en) 2013-03-12 2014-03-11 Compositions for use in treating eye disorders using dipyridamole

Publications (2)

Publication Number Publication Date
EA201591653A1 EA201591653A1 (ru) 2017-05-31
EA035966B1 true EA035966B1 (ru) 2020-09-07

Family

ID=48916407

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201591653A EA035966B1 (ru) 2013-03-12 2014-03-11 Применение фармацевтической композиции для местного применения для лечения расстройств лакримальной системы и переднего отрезка глаза

Country Status (14)

Country Link
EP (1) EP2968328A4 (ko)
JP (1) JP6820658B2 (ko)
KR (2) KR20210010638A (ko)
CN (1) CN105188702B (ko)
AU (1) AU2014229371B2 (ko)
BR (1) BR112015022084A2 (ko)
CA (1) CA2905594A1 (ko)
CL (1) CL2015002627A1 (ko)
EA (1) EA035966B1 (ko)
IL (1) IL225179A (ko)
MX (1) MX2015012716A (ko)
MY (1) MY182591A (ko)
SG (2) SG11201507092QA (ko)
WO (1) WO2014141079A1 (ko)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI725008B (zh) * 2015-01-28 2021-04-21 瑞采生技有限公司 用於增強ＰＰＡＲγ表現及核轉位之化合物及其醫療用途
US20180092776A1 (en) 2016-09-30 2018-04-05 Sara Heikali Method and device for treating and managing diseased ocular tissue
WO2021001806A1 (en) 2019-07-04 2021-01-07 Ocular Discovery Ltd. Stable dipyridamole formulations with reduced impurities
WO2021001805A1 (en) 2019-07-04 2021-01-07 Ocular Discovery Ltd. Stable dipyridamole formulations and their methods of preparation

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA011654B1 (ru) * 2005-02-23 2009-04-28 Хелозайм Терапьютикс, Инк. Растворимые гликозаминогликаназы и способы получения и применения растворимых гликозаминогликаназ
RU2008122978A (ru) * 2005-11-09 2009-12-20 Комбинаторкс, Инкорпорейтед (Us) Способы, композиции и наборы для лечения медицинских состояний

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07258084A (ja) * 1994-03-17 1995-10-09 Rohto Pharmaceut Co Ltd ジピリダモールを必須成分とする眼圧降下剤
US5780450A (en) * 1995-11-21 1998-07-14 Alcon Laboratories, Inc. Use of adenosine uptake inhibitors for treating retinal or optic nerve head damage
WO2010056710A1 (en) * 2008-11-11 2010-05-20 Biovista, Inc. Compositions and methods for treating eye diseases
EP2363126A1 (en) * 2010-03-04 2011-09-07 SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. Composition comprising as active ingredient L-carnitine in combination with hydroxykynurenine-O-beta-DL-glucoside, for the prevention and/or treatment of pathologies of the eye due to ultraviolet radiation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA011654B1 (ru) * 2005-02-23 2009-04-28 Хелозайм Терапьютикс, Инк. Растворимые гликозаминогликаназы и способы получения и применения растворимых гликозаминогликаназ
RU2008122978A (ru) * 2005-11-09 2009-12-20 Комбинаторкс, Инкорпорейтед (Us) Способы, композиции и наборы для лечения медицинских состояний

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MASHKOVSKIY M.D. Lekarstvennye sredstva Posobie dlya vrachey 16-e izdanie, pererabotannoe, ispravlennoe i dopolnennoe, M., "Novaya volna", 2012, p. 485-486, 1216 *

Also Published As

Publication number Publication date
AU2014229371A1 (en) 2015-10-29
WO2014141079A1 (en) 2014-09-18
KR20210010638A (ko) 2021-01-27
MX2015012716A (es) 2016-07-06
SG11201507092QA (en) 2015-10-29
EP2968328A4 (en) 2016-11-23
CL2015002627A1 (es) 2016-03-11
EP2968328A1 (en) 2016-01-20
MY182591A (en) 2021-01-26
IL225179A (en) 2017-01-31
SG10201706937UA (en) 2017-09-28
CN105188702A (zh) 2015-12-23
IL225179A0 (en) 2013-06-27
CA2905594A1 (en) 2014-09-18
JP6820658B2 (ja) 2021-01-27
KR20150126021A (ko) 2015-11-10
EA201591653A1 (ru) 2017-05-31
BR112015022084A2 (pt) 2017-07-18
AU2014229371B2 (en) 2018-05-10
JP2016514123A (ja) 2016-05-19
CN105188702B (zh) 2019-03-26

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