EA031025B1 - Антитела против ntb-a и связанные с ними композиции и способы - Google Patents
Антитела против ntb-a и связанные с ними композиции и способы Download PDFInfo
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- EA031025B1 EA031025B1 EA201591191A EA201591191A EA031025B1 EA 031025 B1 EA031025 B1 EA 031025B1 EA 201591191 A EA201591191 A EA 201591191A EA 201591191 A EA201591191 A EA 201591191A EA 031025 B1 EA031025 B1 EA 031025B1
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- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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| US9603927B2 (en) | 2014-02-28 | 2017-03-28 | Janssen Biotech, Inc. | Combination therapies with anti-CD38 antibodies |
| US9732154B2 (en) | 2014-02-28 | 2017-08-15 | Janssen Biotech, Inc. | Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia |
| AU2015315332A1 (en) * | 2014-09-09 | 2017-03-30 | Board Of Regents, The University Of Texas System | Blocking monoclonal antibodies to AGR2 and its receptor C4.4A |
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| ES2881575T3 (es) * | 2014-09-30 | 2021-11-29 | Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts / Univ Heidelberg | Moléculas de unión, especialmente anticuerpos, que se unen a L1CAM (CD171) |
| WO2016070089A2 (en) * | 2014-10-31 | 2016-05-06 | Abbvie Biotherapeutics Inc. | Anti-cs1 antibodies and antibody drug conjugates |
| EP3227338A4 (en) | 2014-12-04 | 2018-05-16 | Janssen Biotech, Inc. | Anti-cd38 antibodies for treatment of acute myeloid leukemia |
| CR20170526A (es) | 2015-05-20 | 2018-04-03 | Janssen Biotech Inc | ANTICUERPOS ANTI-CD38 PARA EL TRATAMIENTO DE AMILOIDOSIS DE CADENA LIGERA y OTRAS ENFERMEDADES MALIGNAS HEMATOLÓGICAS POSITIVAS PARA CD38 |
| US20170044265A1 (en) * | 2015-06-24 | 2017-02-16 | Janssen Biotech, Inc. | Immune Modulation and Treatment of Solid Tumors with Antibodies that Specifically Bind CD38 |
| SG10202005460RA (en) | 2015-06-30 | 2020-07-29 | Seattle Genetics Inc | Anti-ntb-a antibodies and related compositions and methods |
| PL3827845T3 (pl) | 2015-11-03 | 2022-07-11 | Janssen Biotech, Inc. | Formulacje podskórne przeciwciał anty-cd38 i ich zastosowania |
| CA3079242A1 (en) | 2017-10-31 | 2019-05-09 | Janssen Biotech, Inc. | Methods of treating high risk multiple myeloma |
| US12037410B2 (en) * | 2018-02-13 | 2024-07-16 | Precision Biologics, Inc. | Methods and compositions for targeting Treg cells |
| BR112021024997A2 (pt) | 2019-07-03 | 2022-01-25 | Oxford Biotherapeutics Ltd | Anticorpos, polinucleotídeo, vetor de expressão, célula hospedeira, composição farmacêutica, métodos e uso |
| JP7671284B2 (ja) * | 2019-10-04 | 2025-05-01 | ティーエーイー ライフ サイエンシーズ | Fc変異および部位特異的コンジュゲーション特性を含む抗体組成物 |
| WO2021111005A1 (en) | 2019-12-06 | 2021-06-10 | Thoas Fioretos | Novel agents and uses thereof |
| WO2025149667A1 (en) | 2024-01-12 | 2025-07-17 | Pheon Therapeutics Ltd | Antibody drug conjugates and uses thereof |
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Patent Citations (1)
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| US20110171204A1 (en) * | 2006-08-28 | 2011-07-14 | Arca Biopharma, Inc. | Antibodies to ntb-a |
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| KORVER et al., "The lymphoid cell surface receptor NTB-A a novel monoclonal antibody target for leukaemia and lymphoma therapeutics," British Journal of Haematology, Vol. 137, P. 307-318, 19 April 2007 (19.04.2007), entire document * |
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| CN105188749B (zh) | 2017-12-19 |
| CN107880126B (zh) | 2021-03-30 |
| IL239211A0 (en) | 2015-07-30 |
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| EP2934585A1 (en) | 2015-10-28 |
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| US20150376276A1 (en) | 2015-12-31 |
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| JP6449777B2 (ja) | 2019-01-09 |
| AU2013364043A1 (en) | 2015-06-18 |
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| US20170320944A1 (en) | 2017-11-09 |
| IL239211B (en) | 2020-08-31 |
| JP6817674B2 (ja) | 2021-01-20 |
| EP2934585B1 (en) | 2018-06-13 |
| CA2893977C (en) | 2024-02-13 |
| IL271305A (en) | 2020-01-30 |
| EP2934585A4 (en) | 2016-07-13 |
| US20230105802A1 (en) | 2023-04-06 |
| CN107880126A (zh) | 2018-04-06 |
| JP2020055870A (ja) | 2020-04-09 |
| JP2022066565A (ja) | 2022-04-28 |
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| US20190375841A1 (en) | 2019-12-12 |
| JP2016503067A (ja) | 2016-02-01 |
| JP2019014752A (ja) | 2019-01-31 |
| CA2893977A1 (en) | 2014-06-26 |
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