EA029504B1 - Способ индуцирования иммунного ответа против филовирусного антигена у пациента с использованием аденовирусов серотипа 26 и серотипа 35 - Google Patents
Способ индуцирования иммунного ответа против филовирусного антигена у пациента с использованием аденовирусов серотипа 26 и серотипа 35 Download PDFInfo
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Classifications
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/14011—Filoviridae
- C12N2760/14034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/14011—Filoviridae
- C12N2760/14111—Ebolavirus, e.g. Zaire ebolavirus
- C12N2760/14134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42295410P | 2010-12-14 | 2010-12-14 | |
| PCT/US2011/064944 WO2012082918A1 (en) | 2010-12-14 | 2011-12-14 | Adenovirus serotype 26 and serotype 35 filovirus vaccines |
Publications (2)
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| EA201390866A1 EA201390866A1 (ru) | 2014-05-30 |
| EA029504B1 true EA029504B1 (ru) | 2018-04-30 |
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| EA201390866A EA029504B1 (ru) | 2010-12-14 | 2011-12-14 | Способ индуцирования иммунного ответа против филовирусного антигена у пациента с использованием аденовирусов серотипа 26 и серотипа 35 |
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| EP (1) | EP2655604B1 (https=) |
| JP (2) | JP6054876B2 (https=) |
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| CN (1) | CN103370411B (https=) |
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| BR (1) | BR112013014712B1 (https=) |
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| PL (1) | PL2655604T3 (https=) |
| WO (1) | WO2012082918A1 (https=) |
| ZA (1) | ZA201304260B (https=) |
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| ZA201608812B (en) | 2014-06-26 | 2019-08-28 | Janssen Vaccines & Prevention Bv | Antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau |
| BR112016029579A2 (pt) | 2014-06-26 | 2017-08-22 | Janssen Vaccines & Prevention Bv | anticorpos e fragmentos de ligação ao antígeno que se ligam especificamente à proteína tau associada a microtúbulos |
| PT3188753T (pt) | 2014-09-03 | 2020-03-25 | Bavarian Nordic As | Métodos e composições para induzir imunidade protetora contra infeção por filovírus |
| CA2960096A1 (en) * | 2014-09-03 | 2016-03-10 | Bavarian Nordic A/S | Methods and compositions for enhancing immune responses |
| CN106999571B (zh) | 2014-09-26 | 2020-10-02 | 贝斯以色列护理医疗中心有限公司 | 诱导针对人免疫缺陷病毒感染的保护性免疫性的方法和组合物 |
| DK3271729T3 (da) | 2015-03-18 | 2020-12-14 | Janssen Vaccines & Prevention Bv | Analyser til rekombinante ekspressionssystemer |
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| CN108697591B (zh) | 2016-02-18 | 2022-06-17 | 国际香料和香精公司 | 聚脲胶囊组合物 |
| US11160761B2 (en) | 2016-03-18 | 2021-11-02 | International Flavors & Fragrances Inc. | Silica microcapsules and methods of preparing same |
| MA45381A (fr) | 2016-06-16 | 2021-04-21 | Janssen Vaccines & Prevention Bv | Formulation de vaccin contre le vih |
| BR112018076803B1 (pt) | 2016-07-01 | 2022-05-03 | International Flavors & Fragrances Inc | Composição estável de microcápsula, e, produto de consumo |
| WO2018011198A1 (en) | 2016-07-15 | 2018-01-18 | Janssen Vaccines & Prevention B.V. | Methods and compositions for inducing protective immunity against a marburg virus infection |
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| CN109689197B (zh) | 2016-09-16 | 2023-06-23 | 国际香料和香精公司 | 用粘度控制剂稳定的微胶囊组合物 |
| US20180085291A1 (en) | 2016-09-28 | 2018-03-29 | International Flavors & Fragrances Inc. | Microcapsule compositions containing amino silicone |
| EP3606553A1 (en) | 2017-04-06 | 2020-02-12 | Janssen Vaccines & Prevention B.V. | Mva-bn and ad26.zebov or ad26.filo prime-boost regimen |
| US20180346648A1 (en) | 2017-05-30 | 2018-12-06 | International Flavors & Fragrances Inc. | Branched polyethyleneimine microcapsules |
| KR20200015759A (ko) | 2017-06-15 | 2020-02-12 | 얀센 백신스 앤드 프리벤션 비.브이. | Hiv 항원을 인코딩하는 폭스바이러스 벡터, 및 그 사용 방법 |
| WO2019018724A1 (en) | 2017-07-21 | 2019-01-24 | Janssen Vaccines & Prevention B.V. | METHODS FOR SAFE INDUCTION OF MULTICLADED CROSS-IMMUNITY AGAINST HUMAN IMMUNODEFICIENCY VIRUS INFECTION IN HUMAN BEINGS |
| CN111163799A (zh) | 2017-07-28 | 2020-05-15 | 扬森疫苗与预防公司 | 用于异源repRNA免疫接种的方法和组合物 |
| WO2019099970A1 (en) | 2017-11-20 | 2019-05-23 | Janssen Pharmaceuticals Inc. | Method of providing safe administration of adenoviral vectors encoding a zika virus antigen |
| KR20200100745A (ko) | 2017-12-19 | 2020-08-26 | 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 | B형 간염 바이러스(hbv)에 대한 면역 반응 유도를 위한 방법 및 조성물 |
| WO2019210125A1 (en) | 2018-04-27 | 2019-10-31 | International Flavors & Fragrances Inc. | Stable polyurea microcapsule compositions |
| EP3810277A1 (en) | 2018-07-20 | 2021-04-28 | Janssen Vaccines & Prevention B.V. | Recombinant adenoviral vector expressing zika antigen with improved productivity |
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| US12303856B2 (en) | 2018-12-18 | 2025-05-20 | International Flavors & Fragrances Inc. | Hydroxyethyl cellulose microcapsules |
| BR112021011936A2 (pt) | 2018-12-18 | 2021-09-08 | International Flavors & Fragrances Inc. | Processo para preparar uma composição de microcápsula, composição de microcápsula, e, produto de consumo |
| MX2021013950A (es) | 2019-05-14 | 2022-01-04 | Janssen Biotech Inc | Eliminacion eficaz de impurezas usando un proceso de diafiltracion. |
| JP2023512519A (ja) | 2020-01-31 | 2023-03-27 | ベス イスラエル ディーコネス メディカル センター インコーポレイテッド | コロナウイルス感染症を予防および処置するための組成物および方法－ｓａｒｓ－ｃｏｖ－２ワクチン |
| CA3183086A1 (en) | 2020-05-11 | 2021-11-18 | Janssen Pharmaceuticals, Inc. | Stabilized coronavirus spike protein fusion proteins |
| US20230233661A1 (en) | 2020-06-29 | 2023-07-27 | Janssen Vaccines & Prevention B.V. | Vaccine combination against repiratory syncytial virus infection |
| US20230302119A1 (en) | 2020-07-06 | 2023-09-28 | Janssen Pharmaceuticals, Inc. | Stabilized Corona Virus Spike Protein Fusion Proteins |
| IL299571A (en) | 2020-07-08 | 2023-02-01 | Janssen Sciences Ireland Unlimited Co | Rna replicon vaccines against hbv |
| JP7369276B2 (ja) * | 2020-08-22 | 2023-10-25 | フェデラル ステート バジェタリー インスティテューション“ナショナル リサーチ センター フォー エピデミオロジー アンド マイクロバイオロジー ネームド アフター ザ オナラリー アカデミシャン エヌ．エフ．ガマレヤ”オブ ザ ミニストリー オブ ヘルス オブ ザ ロシアン フェデレーション | 重症急性呼吸器症候群ウイルスｓａｒｓ－ｃｏｖ－２に対する発現ベクター |
| WO2022175479A1 (en) | 2021-02-19 | 2022-08-25 | Janssen Vaccines & Prevention B.V. | Vaccine combinations against respiratory syncytial virus strain a and b infections |
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| KR20230165275A (ko) | 2021-04-01 | 2023-12-05 | 얀센 백신스 앤드 프리벤션 비.브이. | 안정화된 융합 전 piv3 f 단백질 |
| EP4124383A1 (en) | 2021-07-27 | 2023-02-01 | International Flavors & Fragrances Inc. | Biodegradable microcapsules |
| WO2023020939A1 (en) | 2021-08-17 | 2023-02-23 | Janssen Pharmaceuticals, Inc. | Sars-cov-2 vaccines |
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| WO2023047348A1 (en) | 2021-09-24 | 2023-03-30 | Janssen Pharmaceuticals, Inc. | Stabilized corona virus spike protein fusion proteins |
| WO2023111725A1 (en) | 2021-12-14 | 2023-06-22 | Janssen Pharmaceuticals, Inc. | Sars-cov-2 vaccines |
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| WO2023198815A1 (en) | 2022-04-14 | 2023-10-19 | Janssen Vaccines & Prevention B.V. | Sequential administration of adenoviruses |
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| EP4406641A1 (en) | 2023-01-26 | 2024-07-31 | International Flavors & Fragrances Inc. | Biodegradable microcapsules containing low log p fragrance |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2006037038A1 (en) * | 2004-09-27 | 2006-04-06 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Optimized vaccines to provide protection against ebola and other viruses |
| WO2006040330A2 (en) * | 2004-10-13 | 2006-04-20 | Crucell Holland B.V. | Improved adenoviral vectors and uses thereof |
| US20100303857A1 (en) * | 2001-10-01 | 2010-12-02 | Health and Human Services, the Government of the U.S.A. as Represented by the Secretary, Department | Development of a preventive vaccine for filovirus infection in primates |
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| DK1654370T3 (en) * | 2003-08-01 | 2018-08-20 | Government Of The Us Secretary Department Of Health And Human Services | ACCELERATED EBOLA VACCINATION |
| DE602005025512D1 (de) * | 2004-10-13 | 2011-02-03 | Crucell Holland Bv | Verbesserte adenovirusvektoren und deren verwendung |
| EA016648B1 (ru) * | 2004-10-14 | 2012-06-29 | Круселл Холланд Б.В. | Применение дефектного по репликации рекомбинантного аденовируса, содержащего гетерологичную нуклеиновую кислоту, кодирующую антиген cs возбудителя малярии, и белкового антигена, содержащего белок cs или его фрагмент, для лечения или профилактики малярии |
| WO2007104792A2 (en) | 2006-03-16 | 2007-09-20 | Crucell Holland B.V. | Recombinant adenoviruses based on serotype 26 and 48, and use thereof |
| EP1998804B1 (en) * | 2006-03-27 | 2014-04-16 | Crucell Holland B.V. | Compositions comprising a recombinant adenovirus and an adjuvant |
| WO2009092113A2 (en) * | 2008-01-19 | 2009-07-23 | Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods and compositions for the delivery of vaccines to disrupted epithelium |
| DK2655604T3 (en) | 2010-12-14 | 2018-08-06 | Us Gov Health & Human Services | ADENOVIRUS SEROTYPE-26- AND SEROTYPE-35-FILOVIRUS VACCINES |
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| US20100303857A1 (en) * | 2001-10-01 | 2010-12-02 | Health and Human Services, the Government of the U.S.A. as Represented by the Secretary, Department | Development of a preventive vaccine for filovirus infection in primates |
| WO2006037038A1 (en) * | 2004-09-27 | 2006-04-06 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Optimized vaccines to provide protection against ebola and other viruses |
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| WO2012082918A1 (en) | 2012-06-21 |
| US20140017278A1 (en) | 2014-01-16 |
| DK2655604T3 (en) | 2018-08-06 |
| EP2655604A1 (en) | 2013-10-30 |
| PL2655604T3 (pl) | 2019-02-28 |
| JP2017048207A (ja) | 2017-03-09 |
| AU2011343798A1 (en) | 2013-07-11 |
| CA2821289A1 (en) | 2012-06-21 |
| KR20140019304A (ko) | 2014-02-14 |
| CN103370411A (zh) | 2013-10-23 |
| CN103370411B (zh) | 2016-05-04 |
| EP2655604B1 (en) | 2018-05-09 |
| KR101879892B1 (ko) | 2018-08-17 |
| EA201390866A1 (ru) | 2014-05-30 |
| EP2655604A4 (en) | 2015-01-28 |
| BR112013014712B1 (pt) | 2021-03-02 |
| BR112013014712A2 (pt) | 2017-06-06 |
| CA2821289C (en) | 2019-05-21 |
| JP6268258B2 (ja) | 2018-01-24 |
| ES2676196T3 (es) | 2018-07-17 |
| AU2011343798B2 (en) | 2016-07-14 |
| US9701718B2 (en) | 2017-07-11 |
| ZA201304260B (en) | 2021-05-26 |
| JP6054876B2 (ja) | 2016-12-27 |
| JP2014503206A (ja) | 2014-02-13 |
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