EA026443B1 - Меченныелютецием аналоги бомбезина для лучевой терапии - Google Patents
Меченныелютецием аналоги бомбезина для лучевой терапии Download PDFInfo
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- EA026443B1 EA026443B1 EA201300611A EA201300611A EA026443B1 EA 026443 B1 EA026443 B1 EA 026443B1 EA 201300611 A EA201300611 A EA 201300611A EA 201300611 A EA201300611 A EA 201300611A EA 026443 B1 EA026443 B1 EA 026443B1
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Classifications
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- C07K7/04—Linear peptides containing only normal peptide links
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- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
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- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
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- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P13/08—Drugs for disorders of the urinary system of the prostate
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
Landscapes
- Health & Medical Sciences (AREA)
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- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
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- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| EP10075743 | 2010-11-22 | ||
| PCT/EP2011/070553 WO2012069410A1 (en) | 2010-11-22 | 2011-11-21 | 177lutetium-labeled bombesin analogs for radiotherapy |
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| EA201300611A1 EA201300611A1 (ru) | 2014-04-30 |
| EA026443B1 true EA026443B1 (ru) | 2017-04-28 |
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| EA201300611A EA026443B1 (ru) | 2010-11-22 | 2011-11-21 | Меченныелютецием аналоги бомбезина для лучевой терапии |
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| EP (1) | EP2643024A1 (enExample) |
| JP (1) | JP2014500262A (enExample) |
| KR (1) | KR20140053819A (enExample) |
| CN (1) | CN103476434A (enExample) |
| AU (1) | AU2011333948A1 (enExample) |
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| PH (1) | PH12013501018A1 (enExample) |
| SG (1) | SG190371A1 (enExample) |
| WO (1) | WO2012069410A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2100900A1 (en) * | 2008-03-07 | 2009-09-16 | Universitätsspital Basel | Bombesin analog peptide antagonist conjugates |
| PL2900279T3 (pl) | 2012-09-25 | 2020-05-18 | Advanced Accelerator Applications Usa, Inc. | Antagonisty grpr do wykrywania, diagnostyki i leczenia raka grpr-pozytywnego |
| CN106039327A (zh) * | 2016-06-14 | 2016-10-26 | 宁波益格爱生物科技有限公司 | 一种grpr靶向性分子探针及其制备方法 |
| US20190358351A1 (en) * | 2016-11-17 | 2019-11-28 | Minerva Imaging Aps | 177-lu labeled active site inhibited factor vii |
| US20250339567A1 (en) * | 2019-12-19 | 2025-11-06 | Technische Universität München | Compounds with improved pharmacokinetics for imaging and therapy of cancer |
| EP4282439A1 (en) * | 2022-05-23 | 2023-11-29 | Erasmus University Rotterdam Medical Center | Radioisotope labeled sstr2-agonists with linkers |
| CN117919452A (zh) * | 2023-03-09 | 2024-04-26 | 中国科学院宁波材料技术与工程研究所 | 一种亚细胞器主动靶向成像探针及其制备方法 |
| WO2025119203A1 (zh) * | 2023-12-05 | 2025-06-12 | 烟台蓝纳成生物技术有限公司 | 一种异二聚体放射性核素偶联药物、制备及其应用 |
Citations (1)
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| WO2009109332A1 (en) * | 2008-03-07 | 2009-09-11 | Universitätsspital Bern | Bombesin analog peptide antagonist conjugates |
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- 2011-11-21 SG SG2013039508A patent/SG190371A1/en unknown
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- 2011-11-21 PH PH1/2013/501018A patent/PH12013501018A1/en unknown
- 2011-11-21 IN IN1188MUN2013 patent/IN2013MN01188A/en unknown
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2009109332A1 (en) * | 2008-03-07 | 2009-09-11 | Universitätsspital Bern | Bombesin analog peptide antagonist conjugates |
Non-Patent Citations (4)
| Title |
|---|
| ALEXANDRA VARVARIGOU, PENELOPE BOUZIOTIS, CHRISTOS ZIKOS, FRANCESCO SCOPINARO, GIUSEPPE DE VINCENTIS: "Gastrin-Releasing Peptide (GRP) Analogues for Cancer Imaging", CANCER BIOTHERAPY & RADIOPHARMACEUTICALS, vol. 19, no. 2, 1 January 2004 (2004-01-01), pages 219 - 229, XP055017101, DOI: 10.1089/108497804323072002 * |
| PANIGONE S , NUNN A D: "Lutetium-177-labeled gastrin releasing peptide receptor binding analogs: A novel approach to radionuclide therapy", THE QUARTERLY JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, EDIZIONI MINERVA MEDICA, IT, vol. 50, no. 4, 1 December 2006 (2006-12-01), IT, pages 310 - 321, XP002667674, ISSN: 1125-0135 * |
| R. MANSI, X. WANG, F. FORRER, S. KNEIFEL, M.-L. TAMMA, B. WASER, R. CESCATO, J. C. REUBI, H. R. MAECKE: "Evaluation of a 1,4,7,10-Tetraazacyclododecane-1,4,7,10-Tetraacetic Acid-Conjugated Bombesin-Based Radioantagonist for the Labeling with Single-Photon Emission Computed Tomography, Positron Emission Tomography, and Therapeutic Radionuclides", CLINICAL CANCER RESEARCH, ASSOCIATION FOR CANCER RESEARCH, vol. 15, no. 16, 15 August 2009 (2009-08-15), pages 5240 - 5249, XP055009871, ISSN: 10780432, DOI: 10.1158/1078-0432.CCR-08-3145 * |
| ROSALBA MANSI; XUEJUAN WANG; FLAVIO FORRER; BEATRICE WASER; RENZO CESCATO; KEITH GRAHAM; SANDRA BORKOWSKI; JEAN CLAUDE REUBI; HELM: "Development of a potent DOTA-conjugated bombesin antagonist for targeting GRPr-positive tumours", EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, SPRINGER, BERLIN, DE, vol. 38, no. 1, 18 August 2010 (2010-08-18), Berlin, DE, pages 97 - 107, XP019869308, ISSN: 1619-7089, DOI: 10.1007/s00259-010-1596-9 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US20140023585A1 (en) | 2014-01-23 |
| EA201300611A1 (ru) | 2014-04-30 |
| CA2818694A1 (en) | 2012-05-31 |
| NZ610740A (en) | 2015-08-28 |
| PH12013501018A1 (en) | 2017-08-23 |
| IN2013MN01188A (enExample) | 2015-07-10 |
| BR112013012503A2 (pt) | 2016-11-08 |
| CN103476434A (zh) | 2013-12-25 |
| IL226498A0 (en) | 2013-07-31 |
| KR20140053819A (ko) | 2014-05-08 |
| WO2012069410A1 (en) | 2012-05-31 |
| JP2014500262A (ja) | 2014-01-09 |
| MX2013005697A (es) | 2014-08-01 |
| AU2011333948A1 (en) | 2013-06-06 |
| SG190371A1 (en) | 2013-06-28 |
| EP2643024A1 (en) | 2013-10-02 |
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