EA024260B8 - Способ получения n-замещенных 2-(ацетамино)-n'-бензил-3-метоксипропанамидов - Google Patents
Способ получения n-замещенных 2-(ацетамино)-n'-бензил-3-метоксипропанамидовInfo
- Publication number
- EA024260B8 EA024260B8 EA201490990A EA201490990A EA024260B8 EA 024260 B8 EA024260 B8 EA 024260B8 EA 201490990 A EA201490990 A EA 201490990A EA 201490990 A EA201490990 A EA 201490990A EA 024260 B8 EA024260 B8 EA 024260B8
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- production
- methoxypropanamides
- acetylamino
- benzyl
- substituted
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 229960002623 lacosamide Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/16—Preparation of optical isomers
- C07C231/18—Preparation of optical isomers by stereospecific synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11009048 | 2011-11-15 | ||
| PCT/EP2012/072548 WO2013072330A1 (en) | 2011-11-15 | 2012-11-14 | Process for the production of n-substituted 2-(acetylamino)-n'-benzyl-3-methoxypropanamides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| EA201490990A1 EA201490990A1 (ru) | 2014-11-28 |
| EA024260B1 EA024260B1 (ru) | 2016-08-31 |
| EA024260B8 true EA024260B8 (ru) | 2016-11-30 |
Family
ID=47178026
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201490990A EA024260B8 (ru) | 2011-11-15 | 2012-11-14 | Способ получения n-замещенных 2-(ацетамино)-n'-бензил-3-метоксипропанамидов |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP2780318B1 (https=) |
| JP (1) | JP2014533292A (https=) |
| CN (1) | CN103930397B (https=) |
| BR (1) | BR112014011748A2 (https=) |
| EA (1) | EA024260B8 (https=) |
| IL (1) | IL232627A0 (https=) |
| IN (1) | IN2014KN01247A (https=) |
| MX (1) | MX341754B (https=) |
| WO (1) | WO2013072330A1 (https=) |
| ZA (1) | ZA201403237B (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016039393A1 (ja) * | 2014-09-10 | 2016-03-17 | 株式会社エーピーアイ コーポレーション | アミノ酸誘導体の製造方法 |
| CN117964512B (zh) * | 2024-04-01 | 2024-06-04 | 山东惟普控股有限公司 | 一种n,n-二甲基-3-甲氧基丙酰胺的合成方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090143472A1 (en) * | 2007-12-04 | 2009-06-04 | Mukesh Kumar Madhra | Intermediate compounds and their use in preparation of lacosamide |
| WO2010107993A2 (en) * | 2009-03-18 | 2010-09-23 | Pliva Hrvatska D.O.O. | Process for preparing (r)-7v-benzyl-2- (benyloxycarbonylamino)-s-methoxypropionamide |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5656656A (en) | 1992-11-05 | 1997-08-12 | Dompe Farmaceutici S.P.A. | Tartronic acids, their acetalic ethers and O-esters |
| DE4425466A1 (de) | 1994-07-19 | 1996-01-25 | Thomas & Betts Gmbh | Kabel-Steckverbinder |
| EP1642889A1 (en) | 2004-10-02 | 2006-04-05 | Schwarz Pharma Ag | Improved synthesis scheme for lacosamide |
| SG178158A1 (en) | 2009-08-06 | 2012-03-29 | Shell Int Research | Process for preparing an alkylate |
| EP2480524A1 (en) | 2009-09-25 | 2012-08-01 | Cadila Healthcare Limited | Processes for the preparation of lacosamide and intermediates thereof |
-
2012
- 2012-11-14 CN CN201280056152.2A patent/CN103930397B/zh active Active
- 2012-11-14 WO PCT/EP2012/072548 patent/WO2013072330A1/en not_active Ceased
- 2012-11-14 BR BR112014011748A patent/BR112014011748A2/pt not_active Application Discontinuation
- 2012-11-14 JP JP2014541630A patent/JP2014533292A/ja active Pending
- 2012-11-14 EA EA201490990A patent/EA024260B8/ru not_active IP Right Cessation
- 2012-11-14 IN IN1247KON2014 patent/IN2014KN01247A/en unknown
- 2012-11-14 MX MX2014005593A patent/MX341754B/es active IP Right Grant
- 2012-11-14 EP EP12784603.8A patent/EP2780318B1/en active Active
-
2014
- 2014-05-05 ZA ZA2014/03237A patent/ZA201403237B/en unknown
- 2014-05-14 IL IL232627A patent/IL232627A0/en unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090143472A1 (en) * | 2007-12-04 | 2009-06-04 | Mukesh Kumar Madhra | Intermediate compounds and their use in preparation of lacosamide |
| WO2010107993A2 (en) * | 2009-03-18 | 2010-09-23 | Pliva Hrvatska D.O.O. | Process for preparing (r)-7v-benzyl-2- (benyloxycarbonylamino)-s-methoxypropionamide |
Also Published As
| Publication number | Publication date |
|---|---|
| IN2014KN01247A (https=) | 2015-10-16 |
| EA024260B1 (ru) | 2016-08-31 |
| WO2013072330A1 (en) | 2013-05-23 |
| MX2014005593A (es) | 2015-01-22 |
| MX341754B (es) | 2016-09-02 |
| ZA201403237B (en) | 2015-12-23 |
| CN103930397B (zh) | 2015-10-21 |
| CN103930397A (zh) | 2014-07-16 |
| EP2780318A1 (en) | 2014-09-24 |
| JP2014533292A (ja) | 2014-12-11 |
| IL232627A0 (en) | 2014-06-30 |
| EP2780318B1 (en) | 2015-08-26 |
| EA201490990A1 (ru) | 2014-11-28 |
| BR112014011748A2 (pt) | 2017-05-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG TJ TM RU |