MX341754B - Proceso para la produccion de 2-(acetilamino)-n'-bencil-3-metoxipr opanamidas n-sustituidas. - Google Patents

Proceso para la produccion de 2-(acetilamino)-n'-bencil-3-metoxipr opanamidas n-sustituidas.

Info

Publication number
MX341754B
MX341754B MX2014005593A MX2014005593A MX341754B MX 341754 B MX341754 B MX 341754B MX 2014005593 A MX2014005593 A MX 2014005593A MX 2014005593 A MX2014005593 A MX 2014005593A MX 341754 B MX341754 B MX 341754B
Authority
MX
Mexico
Prior art keywords
production
methoxypropanamides
acetylamino
substituted
nzyl
Prior art date
Application number
MX2014005593A
Other languages
English (en)
Other versions
MX2014005593A (es
Inventor
Hermut Wehlan
Kal Rossen
Jan Oehme
Vladimir Kral
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of MX2014005593A publication Critical patent/MX2014005593A/es
Publication of MX341754B publication Critical patent/MX341754B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/16—Preparation of optical isomers
    • C07C231/18—Preparation of optical isomers by stereospecific synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Se describe un proceso para la producción de 2-(acetilamino)-N´-be ncil-3-metoxipropanamidas N-sustituidas y el tratamiento subsecuente con ácidos. Este proceso se puede utilizar para la producción de (R)-Lacosamida.
MX2014005593A 2011-11-15 2012-11-14 Proceso para la produccion de 2-(acetilamino)-n'-bencil-3-metoxipr opanamidas n-sustituidas. MX341754B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11009048 2011-11-15
PCT/EP2012/072548 WO2013072330A1 (en) 2011-11-15 2012-11-14 Process for the production of n-substituted 2-(acetylamino)-n'-benzyl-3-methoxypropanamides

Publications (2)

Publication Number Publication Date
MX2014005593A MX2014005593A (es) 2015-01-22
MX341754B true MX341754B (es) 2016-09-02

Family

ID=47178026

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014005593A MX341754B (es) 2011-11-15 2012-11-14 Proceso para la produccion de 2-(acetilamino)-n'-bencil-3-metoxipr opanamidas n-sustituidas.

Country Status (10)

Country Link
EP (1) EP2780318B1 (es)
JP (1) JP2014533292A (es)
CN (1) CN103930397B (es)
BR (1) BR112014011748A2 (es)
EA (1) EA024260B8 (es)
IL (1) IL232627A0 (es)
IN (1) IN2014KN01247A (es)
MX (1) MX341754B (es)
WO (1) WO2013072330A1 (es)
ZA (1) ZA201403237B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2016039393A1 (ja) * 2014-09-10 2017-06-22 株式会社エーピーアイ コーポレーション アミノ酸誘導体の製造方法
CN117964512B (zh) * 2024-04-01 2024-06-04 山东惟普控股有限公司 一种n,n-二甲基-3-甲氧基丙酰胺的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0667850B1 (en) 1992-11-05 1997-05-28 Dompe Farmaceutici S.P.A. Tartronic acids, their acetalic ethers and o-esters
DE4425466A1 (de) 1994-07-19 1996-01-25 Thomas & Betts Gmbh Kabel-Steckverbinder
EP1642889A1 (en) 2004-10-02 2006-04-05 Schwarz Pharma Ag Improved synthesis scheme for lacosamide
US8093426B2 (en) * 2007-12-04 2012-01-10 Ranbaxy Laboratories Limited Intermediate compounds and their use in preparation of lacosamide
WO2010107993A2 (en) 2009-03-18 2010-09-23 Pliva Hrvatska D.O.O. Process for preparing (r)-7v-benzyl-2- (benyloxycarbonylamino)-s-methoxypropionamide
SG178158A1 (en) 2009-08-06 2012-03-29 Shell Int Research Process for preparing an alkylate
US8853439B2 (en) 2009-09-25 2014-10-07 Cadila Healthcare Limited Processes for the preparation of lacosamide and intermediates thereof

Also Published As

Publication number Publication date
EP2780318B1 (en) 2015-08-26
IL232627A0 (en) 2014-06-30
CN103930397B (zh) 2015-10-21
EP2780318A1 (en) 2014-09-24
BR112014011748A2 (pt) 2017-05-30
EA024260B1 (ru) 2016-08-31
IN2014KN01247A (es) 2015-10-16
MX2014005593A (es) 2015-01-22
ZA201403237B (en) 2015-12-23
EA201490990A1 (ru) 2014-11-28
CN103930397A (zh) 2014-07-16
JP2014533292A (ja) 2014-12-11
WO2013072330A1 (en) 2013-05-23
EA024260B8 (ru) 2016-11-30

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