EA023648B1 - ИНДАНИЛЗАМЕЩЕННЫЕ 4,5,6,7-ТЕТРАГИДРО-1H-ПИРАЗОЛО[4,3-с]ПИРИДИНЫ, ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ЛЕКАРСТВЕННОГО СРЕДСТВА И СОДЕРЖАЩИЕ ИХ ФАРМАЦЕВТИЧЕСКИЕ ПРЕПАРАТЫ - Google Patents

ИНДАНИЛЗАМЕЩЕННЫЕ 4,5,6,7-ТЕТРАГИДРО-1H-ПИРАЗОЛО[4,3-с]ПИРИДИНЫ, ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ЛЕКАРСТВЕННОГО СРЕДСТВА И СОДЕРЖАЩИЕ ИХ ФАРМАЦЕВТИЧЕСКИЕ ПРЕПАРАТЫ Download PDF

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Publication number
EA023648B1
EA023648B1 EA201490621A EA201490621A EA023648B1 EA 023648 B1 EA023648 B1 EA 023648B1 EA 201490621 A EA201490621 A EA 201490621A EA 201490621 A EA201490621 A EA 201490621A EA 023648 B1 EA023648 B1 EA 023648B1
Authority
EA
Eurasian Patent Office
Prior art keywords
hydroxyindan
difluoro
pyridin
tetrahydro
alkyl
Prior art date
Application number
EA201490621A
Other languages
English (en)
Russian (ru)
Other versions
EA201490621A1 (ru
Inventor
Лоран Биали
Йозеф Пернершторфер
Клаус Вирт
Клаус Стайнмайер
Герхард Хесслер
Original Assignee
Санофи
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Санофи filed Critical Санофи
Publication of EA201490621A1 publication Critical patent/EA201490621A1/ru
Publication of EA023648B1 publication Critical patent/EA023648B1/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EA201490621A 2011-09-12 2012-09-10 ИНДАНИЛЗАМЕЩЕННЫЕ 4,5,6,7-ТЕТРАГИДРО-1H-ПИРАЗОЛО[4,3-с]ПИРИДИНЫ, ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ЛЕКАРСТВЕННОГО СРЕДСТВА И СОДЕРЖАЩИЕ ИХ ФАРМАЦЕВТИЧЕСКИЕ ПРЕПАРАТЫ EA023648B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11306129 2011-09-12
PCT/EP2012/067654 WO2013037736A1 (fr) 2011-09-12 2012-09-10 4,5,6,7-tétrahydro-1h-pyrazolo[4,3-c]pyridines substituées avec un indanyle, leur utilisation comme médicament, et préparations pharmaceutiques les contenant

Publications (2)

Publication Number Publication Date
EA201490621A1 EA201490621A1 (ru) 2014-08-29
EA023648B1 true EA023648B1 (ru) 2016-06-30

Family

ID=46829768

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201490621A EA023648B1 (ru) 2011-09-12 2012-09-10 ИНДАНИЛЗАМЕЩЕННЫЕ 4,5,6,7-ТЕТРАГИДРО-1H-ПИРАЗОЛО[4,3-с]ПИРИДИНЫ, ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ЛЕКАРСТВЕННОГО СРЕДСТВА И СОДЕРЖАЩИЕ ИХ ФАРМАЦЕВТИЧЕСКИЕ ПРЕПАРАТЫ

Country Status (4)

Country Link
BR (1) BR112014005583A2 (fr)
EA (1) EA023648B1 (fr)
MX (1) MX2014002968A (fr)
WO (1) WO2013037736A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017097792A1 (fr) 2015-12-10 2017-06-15 Bayer Pharma Aktiengesellschaft Dérivés de 2-phényl-3-(pipérazinométhyl)imidazo[1,2-a]pyridine utilisés comme bloqueurs des canaux task-1 et task-2 pour traiter des troubles respiratoires liés au sommeil
EP3386993A1 (fr) 2015-12-10 2018-10-17 Bayer Pharma Aktiengesellschaft Dérivés de perhydropyrrolo[3,4-c]pyrrole substitués et leur utilisation
JOP20190284A1 (ar) 2017-06-14 2019-12-11 Bayer Pharma AG مركبات إيميدازوبيريميدين مستبدلة بديازا ثنائي الحلقة واستخدامها للمعالجة من اضطرابات التنفس

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0086422A2 (fr) * 1982-02-17 1983-08-24 GRUPPO LEPETIT S.p.A. Pyrazolo (4,3-c)pyridines à activité pharmacologique
WO2007124849A2 (fr) * 2006-04-27 2007-11-08 Sanofi-Aventis Deutschland Gmbh Inhibiteurs du canal ionique task-1 et task-3

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10332685A1 (de) 2003-07-18 2005-02-17 Bayer Healthcare Ag Vorhof-selektiv exprimierte Kaliumkanäle
DE102005028862A1 (de) 2005-06-22 2007-01-11 Sanofi-Aventis Deutschland Gmbh Substituierte Heterocyclen, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen
KR20110050718A (ko) 2008-09-02 2011-05-16 사노피-아벤티스 치환된 아미노인단 및 그의 유사체, 및 그의 제약 용도

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0086422A2 (fr) * 1982-02-17 1983-08-24 GRUPPO LEPETIT S.p.A. Pyrazolo (4,3-c)pyridines à activité pharmacologique
WO2007124849A2 (fr) * 2006-04-27 2007-11-08 Sanofi-Aventis Deutschland Gmbh Inhibiteurs du canal ionique task-1 et task-3

Also Published As

Publication number Publication date
BR112014005583A2 (pt) 2017-03-21
EA201490621A1 (ru) 2014-08-29
WO2013037736A1 (fr) 2013-03-21
MX2014002968A (es) 2014-07-09

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU