EA018918B1 - КОМБИНАЦИЯ, СОДЕРЖАЩАЯ β-АГОНИСТ И ПРОГЕСТИН, И ЕЁ ПРИМЕНЕНИЕ ДЛЯ ЛЕЧЕНИЯ ИЛИ ПРЕДОТВРАЩЕНИЯ АТРОФИИ МЫШЕЧНОЙ ТКАНИ - Google Patents
КОМБИНАЦИЯ, СОДЕРЖАЩАЯ β-АГОНИСТ И ПРОГЕСТИН, И ЕЁ ПРИМЕНЕНИЕ ДЛЯ ЛЕЧЕНИЯ ИЛИ ПРЕДОТВРАЩЕНИЯ АТРОФИИ МЫШЕЧНОЙ ТКАНИ Download PDFInfo
- Publication number
- EA018918B1 EA018918B1 EA200970957A EA200970957A EA018918B1 EA 018918 B1 EA018918 B1 EA 018918B1 EA 200970957 A EA200970957 A EA 200970957A EA 200970957 A EA200970957 A EA 200970957A EA 018918 B1 EA018918 B1 EA 018918B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- combination according
- agonist
- progestin
- atrophy
- muscle tissue
- Prior art date
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Classifications
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- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
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- Organic Chemistry (AREA)
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- Nutrition Science (AREA)
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- AIDS & HIV (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Immunology (AREA)
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| GB0707931A GB0707931D0 (en) | 2007-04-24 | 2007-04-24 | New Therapeutic use |
| GB0707930A GB0707930D0 (en) | 2007-04-24 | 2007-04-24 | New therapeutic use |
| GB0710101A GB0710101D0 (en) | 2007-05-25 | 2007-05-25 | New Therapeutic use |
| PCT/GB2008/001452 WO2008129308A2 (en) | 2007-04-24 | 2008-04-24 | Drug combination and its use in the treatment of muscle loss |
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| EA018918B1 true EA018918B1 (ru) | 2013-11-29 |
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| EP (1) | EP2155180B1 (OSRAM) |
| JP (1) | JP5627452B2 (OSRAM) |
| KR (1) | KR101546977B1 (OSRAM) |
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| AU (1) | AU2008240379B2 (OSRAM) |
| BR (1) | BRPI0810461A2 (OSRAM) |
| CA (1) | CA2721739C (OSRAM) |
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| IL (1) | IL201426A (OSRAM) |
| MX (1) | MX2009011294A (OSRAM) |
| NZ (1) | NZ580975A (OSRAM) |
| WO (1) | WO2008129308A2 (OSRAM) |
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| ATE457169T1 (de) | 1998-10-15 | 2010-02-15 | Imp Innovations Ltd | Verbindungen für die behandlung von gewichtsverlust |
| ES2384641T3 (es) | 2005-07-14 | 2012-07-10 | Lithera, Inc. | Formulación lipolítica que potencia la liberación mantenida para el tratamiento localizado del tejido adiposo |
| GB0624282D0 (en) | 2006-12-05 | 2007-01-10 | Cavalla David | Treatment of cachexia |
| EP2646012A4 (en) * | 2010-11-24 | 2014-12-10 | Neothetics Inc | MONOTHERAPEUTIC FORMULATIONS OF SELECTIVE, LIPOPHILIC AND PROLONGED BETA AGONISTS AND METHODS OF COSMETIC TREATMENT OF SILHOUETTE ADPOSITY AND REINFORCEMENT |
| RU2695649C2 (ru) * | 2014-08-05 | 2019-07-25 | Раквалиа Фарма Инк. | Производные серина в качестве агонистов грелиновых рецепторов |
| US11400060B2 (en) * | 2020-01-13 | 2022-08-02 | Astromedical Biotechnology, Ltd. | Use of ketamine in the treatment of cachexia |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006003222A1 (es) * | 2004-06-29 | 2006-01-12 | Universidad De Barcelona | Uso del formoterol en el tratamiento profiláctico y/o terapéutico del desgaste muscular y/o síndrome caquéctico, asociados a estados catabólicos de ciertas enfermedades como cáncer, sida, infecciones, diabetes y otras |
| US7101576B2 (en) * | 2002-04-12 | 2006-09-05 | Elan Pharma International Limited | Nanoparticulate megestrol formulations |
| WO2007095497A2 (en) * | 2006-02-13 | 2007-08-23 | Anaborex Inc. | Compositions and methods for prevention and treatment of cachexia |
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| ATE149089T1 (de) | 1987-09-15 | 1997-03-15 | Rowett Research Inst | Anwendungsgebiete von beta-adrenergenen agonisten |
| CA2481390C (en) * | 2002-04-12 | 2012-11-27 | Elan Pharma International Ltd. | Nanoparticulate megestrol formulations |
| US8080528B2 (en) * | 2005-12-22 | 2011-12-20 | The Releef Initiative | Compositions and methods for treatment of cachexia |
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- 2008-04-24 US US12/594,985 patent/US8653052B2/en not_active Expired - Fee Related
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- 2008-04-24 CN CN201410490740.8A patent/CN104306381A/zh active Pending
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7101576B2 (en) * | 2002-04-12 | 2006-09-05 | Elan Pharma International Limited | Nanoparticulate megestrol formulations |
| WO2006003222A1 (es) * | 2004-06-29 | 2006-01-12 | Universidad De Barcelona | Uso del formoterol en el tratamiento profiláctico y/o terapéutico del desgaste muscular y/o síndrome caquéctico, asociados a estados catabólicos de ciertas enfermedades como cáncer, sida, infecciones, diabetes y otras |
| WO2007095497A2 (en) * | 2006-02-13 | 2007-08-23 | Anaborex Inc. | Compositions and methods for prevention and treatment of cachexia |
Non-Patent Citations (7)
| Title |
|---|
| ARGILES J.M. ET AL.: "THE PHARMACOLOGICAL TREATMENT OF CACHEXIA". CURRENT DRUG TARGETS, BENTHAM SCIENCE PUBLISHER, US, vol. 5, no. 3, 1 April 2004 (2004-04-01), pages 265-277, XP008033065, ISSN: 1389-4501, page 265, column 2, paragraph 6 - page 266, column 1, paragraph 1 - page 273, paragraph 2 - page 266, column 2, paragraph 1 - paragraph 2 - page 267, column 2, paragraph 2 - page 268, column 2, paragraph 2 * |
| BUSQUETS S. ET AL.: "Anticachectic effects of formoterol: a drug for potential treatment of muscle wasting". CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER RESEARCH, BALTIMORE, MD.; US, vol. 64, no. 18, 15 September, 2004 (2004-09-15), pages 6725-6731, XP003013527, ISSN: 0008-5472, abstract * |
| GOMEZ FRANCISCO ET AL.: "Treatment with megestrol acetate improves human immunodeficiency virus-associated immune thrombocytopenia". CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 9, no. 3, 1 May, 2002 (2002-05-01), pages 583-587, XP008102283, ISSN: 1071-412X, abstract * |
| HARCOURT ET AL.: "Low dose formoterol administration improves muscle function in dystrophic mdx mice without increasing fatigue". NEUROMUSCULAR DISORDERS, PERGAMON PRESS, GB, vol. 17, no. 1, 2 February 2007 (2007-02-02), pages 47-55, XP005870702, ISSN: 0960-8966, page 54, column 1, paragraph 2, abstract * |
| MANTOVANI G. ET AL.: "Medroxyprogesterone Acetate Reduces the In Vitro Production of Cytokines and Serotonin Involved in Anorexia/cachexia and Emesis by Peripheral Blood Mononuclear Cells of Cancer Patients". EUROPEAN JOURNAL OF CANCER, PERGAMON PRESS, OXFORD, GB, vol. 33, no. 4, 1 April, 1997 (1997-04-01), pages 602-607, XP004282563, ISSN: 0959-8049, abstract * |
| RYALL JAMES G. ET AL.: "Systemic administration of beta(2)-adrenoceptor agonists, formoterol and salmeterol, elicit skeletal muscle hypertrophy in rats at micromolar doses". BRITISH JOURNAL OF PHARMACOLOGY, vol. 147, no. 6, March 2006 (2006-03), pages 587-595, XP008106070, ISSN: 0007-1188, abstract * |
| TOMISKA M. ET AL.: "Palliative treatment of cancer anorexia with oral suspension of megestrol acetate". NEOPLASMA, SCIENCES, vol. 50, no. 3, 1 January, 2003 (2003-01-01), pages 227-233, XP009111489, ISSN: 0028-2685, abstract * |
Also Published As
| Publication number | Publication date |
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| EP2155180B1 (en) | 2016-07-13 |
| EP2155180A2 (en) | 2010-02-24 |
| DK2155180T3 (en) | 2016-09-12 |
| CA2721739A1 (en) | 2008-10-30 |
| MX2009011294A (es) | 2010-01-29 |
| KR101546977B1 (ko) | 2015-08-24 |
| KR20100017205A (ko) | 2010-02-16 |
| ES2592289T3 (es) | 2016-11-29 |
| WO2008129308A3 (en) | 2009-12-17 |
| IL201426A0 (en) | 2010-05-31 |
| EA200970957A1 (ru) | 2010-04-30 |
| IL201426A (en) | 2016-09-29 |
| HK1202262A1 (en) | 2015-09-25 |
| US20100130456A1 (en) | 2010-05-27 |
| CA2721739C (en) | 2016-08-23 |
| JP2010525044A (ja) | 2010-07-22 |
| JP5627452B2 (ja) | 2014-11-19 |
| CN104306381A (zh) | 2015-01-28 |
| WO2008129308A2 (en) | 2008-10-30 |
| BRPI0810461A2 (pt) | 2014-10-14 |
| US8653052B2 (en) | 2014-02-18 |
| NZ580975A (en) | 2012-10-26 |
| AU2008240379B2 (en) | 2012-10-04 |
| AU2008240379A1 (en) | 2008-10-30 |
| CN101730547A (zh) | 2010-06-09 |
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