EA017564B1 - Способ ингибирования клостридиум диффициле введением оритаванцина - Google Patents
Способ ингибирования клостридиум диффициле введением оритаванцина Download PDFInfo
- Publication number
- EA017564B1 EA017564B1 EA201000383A EA201000383A EA017564B1 EA 017564 B1 EA017564 B1 EA 017564B1 EA 201000383 A EA201000383 A EA 201000383A EA 201000383 A EA201000383 A EA 201000383A EA 017564 B1 EA017564 B1 EA 017564B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- clostridium difficile
- oritavancin
- spores
- glycopeptide antibiotic
- vancomycin
- Prior art date
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- 235000011121 sodium hydroxide Nutrition 0.000 description 1
- RYYKJJJTJZKILX-UHFFFAOYSA-M sodium octadecanoate Chemical class [Na+].CCCCCCCCCCCCCCCCCC([O-])=O RYYKJJJTJZKILX-UHFFFAOYSA-M 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
- 235000011008 sodium phosphates Nutrition 0.000 description 1
- YVOFSHPIJOYKSH-NLYBMVFSSA-M sodium rifomycin sv Chemical compound [Na+].OC1=C(C(O)=C2C)C3=C([O-])C=C1NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@@H](OC)\C=C\O[C@@]1(C)OC2=C3C1=O YVOFSHPIJOYKSH-NLYBMVFSSA-M 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
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- LSNNMFCWUKXFEE-UHFFFAOYSA-L sulfite Chemical class [O-]S([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-L 0.000 description 1
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- 125000004434 sulfur atom Chemical group 0.000 description 1
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- 230000009469 supplementation Effects 0.000 description 1
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- 238000013268 sustained release Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
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- 108010089019 telavancin Proteins 0.000 description 1
- 229960005240 telavancin Drugs 0.000 description 1
- ONUMZHGUFYIKPM-MXNFEBESSA-N telavancin Chemical compound O1[C@@H](C)[C@@H](O)[C@](NCCNCCCCCCCCCC)(C)C[C@@H]1O[C@H]1[C@H](OC=2C3=CC=4[C@H](C(N[C@H]5C(=O)N[C@H](C(N[C@@H](C6=CC(O)=C(CNCP(O)(O)=O)C(O)=C6C=6C(O)=CC=C5C=6)C(O)=O)=O)[C@H](O)C5=CC=C(C(=C5)Cl)O3)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](NC(=O)[C@@H](CC(C)C)NC)[C@H](O)C3=CC=C(C(=C3)Cl)OC=2C=4)O[C@H](CO)[C@@H](O)[C@@H]1O ONUMZHGUFYIKPM-MXNFEBESSA-N 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
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- 125000000383 tetramethylene group Chemical group [H]C([H])([*:1])C([H])([H])C([H])([H])C([H])([H])[*:2] 0.000 description 1
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- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 description 1
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- 238000002604 ultrasonography Methods 0.000 description 1
- 238000010200 validation analysis Methods 0.000 description 1
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- 239000011709 vitamin E Substances 0.000 description 1
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- 239000008215 water for injection Substances 0.000 description 1
- 239000009637 wintergreen oil Substances 0.000 description 1
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- 235000010447 xylitol Nutrition 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Agronomy & Crop Science (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Dentistry (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US97176607P | 2007-09-12 | 2007-09-12 | |
| PCT/US2008/075949 WO2009036121A1 (en) | 2007-09-12 | 2008-09-11 | Method of inhibiting clostridium difficile by administration of oritavancin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA201000383A1 EA201000383A1 (ru) | 2010-10-29 |
| EA017564B1 true EA017564B1 (ru) | 2013-01-30 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201000383A EA017564B1 (ru) | 2007-09-12 | 2008-09-11 | Способ ингибирования клостридиум диффициле введением оритаванцина |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US8518873B2 (https=) |
| EP (1) | EP2195004B1 (https=) |
| JP (1) | JP5591112B2 (https=) |
| CN (1) | CN102316885A (https=) |
| AU (1) | AU2008298987B2 (https=) |
| CA (1) | CA2699550C (https=) |
| EA (1) | EA017564B1 (https=) |
| ES (1) | ES2535928T3 (https=) |
| WO (1) | WO2009036121A1 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009036121A1 (en) * | 2007-09-12 | 2009-03-19 | Targanta Therapeutics Corp. | Method of inhibiting clostridium difficile by administration of oritavancin |
| ES2884673T3 (es) * | 2008-04-08 | 2021-12-10 | Melinta Therapeutics Inc | Oritavancina para inhibir y tratar biopelículas |
| US9682061B2 (en) | 2009-04-28 | 2017-06-20 | The Medicines Company | Methods of treating bacterial infections using oritavancin |
| JP5986416B2 (ja) * | 2012-04-11 | 2016-09-06 | 花王株式会社 | 皮膚外用剤 |
| US8906668B2 (en) | 2012-11-23 | 2014-12-09 | Seres Health, Inc. | Synergistic bacterial compositions and methods of production and use thereof |
| SG11201503966PA (en) | 2012-11-23 | 2015-06-29 | Seres Health Inc | Synergistic bacterial compositions and methods of production and use thereof |
| JP2016509003A (ja) * | 2013-02-04 | 2016-03-24 | セレス セラピューティクス インコーポレイテッド | 組成物および方法 |
| US10973861B2 (en) | 2013-02-04 | 2021-04-13 | Seres Therapeutics, Inc. | Compositions and methods |
| WO2014145958A2 (en) | 2013-03-15 | 2014-09-18 | Seres Health, Inc. | Network-based microbial compositions and methods |
| CN105979952B (zh) | 2013-11-25 | 2022-04-08 | 赛里斯治疗公司 | 协同细菌组合物以及其制造方法和用途 |
| US9956282B2 (en) | 2013-12-16 | 2018-05-01 | Seres Therapeutics, Inc. | Bacterial compositions and methods of use thereof for treatment of immune system disorders |
| EP3208659A1 (en) * | 2014-10-14 | 2017-08-23 | AZ Electronic Materials (Luxembourg) S.à.r.l. | Composition for resist patterning and method for forming pattern using same |
| GB201509326D0 (en) | 2015-05-29 | 2015-07-15 | Antibio Tx Aps | Novel use |
| CN108712909A (zh) | 2016-02-18 | 2018-10-26 | 梅琳塔治疗公司 | 奥利万星制剂 |
| CN107325159A (zh) * | 2016-04-29 | 2017-11-07 | 中国科学院上海药物研究所 | 一类万古霉素衍生物、其制备方法、药物组合物和用途 |
| KR20190005940A (ko) | 2016-05-09 | 2019-01-16 | 셀리아 파마슈티칼즈 에이피에스 | 안정화된 글리코펩티드 항생제 제형 |
| EP3668527A1 (en) | 2017-08-14 | 2020-06-24 | Seres Therapeutics, Inc. | Compositions and methods for treating cholestatic disease |
| BR112020008552A2 (pt) | 2017-10-30 | 2020-12-29 | Seres Therapeutics, Inc. | métodos e composições para tratamento de resistência a antibiótico |
| EP3836947A4 (en) * | 2018-08-17 | 2022-04-20 | Universidad Andres Bello | METHOD AND PHARMACOLOGICAL COMPOSITION FOR THE PREVENTION OF RECURRING INFECTIONS CAUSED BY CLOSTRIDIUM DIFFICILE |
| KR102444119B1 (ko) * | 2020-04-22 | 2022-09-16 | 주식회사 인트론바이오테크놀로지 | 클로스트리디오이데스 디피실리 균에 대하여 용균 활성을 갖는 항균단백질 cdl200 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050197333A1 (en) * | 2003-12-23 | 2005-09-08 | Van Duzer John H. | Rifamycin analogs and uses thereof |
| US20070014849A1 (en) * | 2002-06-06 | 2007-01-18 | Daniela Jabes | Use of ramoplanin to treat diseases associated with the use of antibiotics |
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| JP2961184B2 (ja) * | 1990-05-07 | 1999-10-12 | ミヤリサン株式会社 | クロストリジウム・ディフィシル下痢症および偽膜性大腸炎の予防ならびに治療用医薬組成物 |
| GB0212622D0 (en) * | 2002-05-31 | 2002-07-10 | Natural Technologies Group Ltd | Bacterial transforming agent |
| US20040106590A1 (en) * | 2002-08-29 | 2004-06-03 | Barry Eisenstein | Methods and reagents for treating infections of clostridium difficile and diseases associated therewith |
| JP2009526069A (ja) * | 2006-02-08 | 2009-07-16 | バイオシネクサス インコーポレーティッド | 細菌胞子の中和 |
| GB0714030D0 (en) * | 2007-07-18 | 2007-08-29 | Novacta Biosystems Ltd | The use of type-B lantibiotic-based compounds having antimicrobial activity |
| WO2009036121A1 (en) * | 2007-09-12 | 2009-03-19 | Targanta Therapeutics Corp. | Method of inhibiting clostridium difficile by administration of oritavancin |
-
2008
- 2008-09-11 WO PCT/US2008/075949 patent/WO2009036121A1/en not_active Ceased
- 2008-09-11 JP JP2010524973A patent/JP5591112B2/ja active Active
- 2008-09-11 EA EA201000383A patent/EA017564B1/ru unknown
- 2008-09-11 EP EP08830916.6A patent/EP2195004B1/en active Active
- 2008-09-11 CA CA2699550A patent/CA2699550C/en active Active
- 2008-09-11 ES ES08830916.6T patent/ES2535928T3/es active Active
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2013
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- 2013-12-10 US US14/101,645 patent/US9220749B2/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070014849A1 (en) * | 2002-06-06 | 2007-01-18 | Daniela Jabes | Use of ramoplanin to treat diseases associated with the use of antibiotics |
| US20050197333A1 (en) * | 2003-12-23 | 2005-09-08 | Van Duzer John H. | Rifamycin analogs and uses thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0816662A2 (pt) | 2017-06-13 |
| US20100311646A1 (en) | 2010-12-09 |
| EA201000383A1 (ru) | 2010-10-29 |
| JP2010539179A (ja) | 2010-12-16 |
| US8518873B2 (en) | 2013-08-27 |
| ES2535928T3 (es) | 2015-05-19 |
| CA2699550A1 (en) | 2009-03-19 |
| US9220749B2 (en) | 2015-12-29 |
| US20130310308A1 (en) | 2013-11-21 |
| AU2008298987A1 (en) | 2009-03-19 |
| EP2195004A4 (en) | 2011-12-28 |
| EP2195004B1 (en) | 2015-04-01 |
| WO2009036121A1 (en) | 2009-03-19 |
| CN102316885A (zh) | 2012-01-11 |
| JP5591112B2 (ja) | 2014-09-17 |
| CA2699550C (en) | 2020-08-18 |
| AU2008298987B2 (en) | 2013-12-05 |
| EP2195004A1 (en) | 2010-06-16 |
| US20140100157A1 (en) | 2014-04-10 |
| US8629100B2 (en) | 2014-01-14 |
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| PC4A | Registration of transfer of a eurasian patent by assignment |