EA015673B1 - Способ стереоселективного получения (-)-галофената и его интермедиатов - Google Patents
Способ стереоселективного получения (-)-галофената и его интермедиатов Download PDFInfo
- Publication number
- EA015673B1 EA015673B1 EA200800884A EA200800884A EA015673B1 EA 015673 B1 EA015673 B1 EA 015673B1 EA 200800884 A EA200800884 A EA 200800884A EA 200800884 A EA200800884 A EA 200800884A EA 015673 B1 EA015673 B1 EA 015673B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- formula
- compound
- group
- groups
- subscript
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72030005P | 2005-09-23 | 2005-09-23 | |
| US11/525,200 US7714131B2 (en) | 2005-09-23 | 2006-09-20 | Process for the stereoselective preparation of (−)-halofenate and derivatives thereof |
| PCT/US2006/036928 WO2007038243A1 (en) | 2005-09-23 | 2006-09-21 | Process for the stereoselective preparation of (-)-halofenate and intermediates thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA200800884A1 EA200800884A1 (ru) | 2008-12-30 |
| EA015673B1 true EA015673B1 (ru) | 2011-10-31 |
Family
ID=37894903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200800884A EA015673B1 (ru) | 2005-09-23 | 2006-09-21 | Способ стереоселективного получения (-)-галофената и его интермедиатов |
Country Status (18)
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009121940A1 (en) * | 2008-04-03 | 2009-10-08 | Janssen Pharmaceutica Nv | Process for the preparation of (-)-(4-chloro-phenyl)-(3-trifluoromethyl-phenoxy)-acetic acid 2-acetylamino-ethyl ester |
| WO2009148046A1 (ja) * | 2008-06-03 | 2009-12-10 | 株式会社カネカ | 光学活性アミノ酸誘導体の製造方法 |
| US9060987B2 (en) | 2011-11-04 | 2015-06-23 | Cymabay Therapeutics, Inc. | Methods for treating gout flares |
| US9023856B2 (en) | 2011-11-04 | 2015-05-05 | Cymabay Therapeutics, Inc. | Methods for treating hyperuricemia in patients with gout using halofenate or halogenic acid and a second urate-lowering agent |
| WO2021236394A1 (en) | 2020-05-18 | 2021-11-25 | Cymabay Therapeutics, Inc. | Cb-0406 tromethamine salt |
| US20210355066A1 (en) | 2020-05-18 | 2021-11-18 | Cymabay Therapeutics, Inc. | CB-0406 choline salt |
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| NL6712585A (US07714131-20100511-C00001.png) | 1966-10-03 | 1968-04-04 | ||
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| DE3525284A1 (de) | 1985-07-16 | 1987-01-29 | Boehringer Mannheim Gmbh | Neue carbonsaeurederivate, verfahren zu ihrer herstellung, ihre verwendung sowie arzneimittel, die diese verbindungen enthalten |
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| JPH01305069A (ja) | 1988-05-31 | 1989-12-08 | Shionogi & Co Ltd | ベンゾトリアゾール誘導体およびそれを含有する発螢光試薬 |
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| US5278314A (en) | 1991-02-12 | 1994-01-11 | Ciba-Geigy Corporation | 5-thio-substituted benzotriazole UV-absorbers |
| DE4111026A1 (de) | 1991-04-05 | 1992-10-08 | Boehringer Mannheim Gmbh | Optisch aktive carbonsaeuren sowie diese enthaltende arzneimittel |
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| EP0559927B1 (en) | 1992-03-09 | 1997-03-05 | Hoechst Aktiengesellschaft | A simplified method for the production of vinyl glycine (2-aminobut-3-enioc acid) and a convenient resolution of a derivative |
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| CA2529774C (en) | 2003-06-20 | 2014-05-27 | Metabolex, Inc. | Resolution of .alpha.-(phenoxy)phenylacetic acid derivatives |
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-
2006
- 2006-09-20 US US11/525,200 patent/US7714131B2/en not_active Expired - Fee Related
- 2006-09-21 PL PL06815150T patent/PL1940387T3/pl unknown
- 2006-09-21 EP EP06815150A patent/EP1940387B1/en active Active
- 2006-09-21 ES ES06815150T patent/ES2394973T3/es active Active
- 2006-09-21 EA EA200800884A patent/EA015673B1/ru not_active IP Right Cessation
- 2006-09-21 SI SI200631502T patent/SI1940387T1/sl unknown
- 2006-09-21 JP JP2008532404A patent/JP2009515817A/ja not_active Withdrawn
- 2006-09-21 BR BRPI0616188-0A patent/BRPI0616188A2/pt not_active IP Right Cessation
- 2006-09-21 AU AU2006294950A patent/AU2006294950A1/en not_active Abandoned
- 2006-09-21 RS RS20130001A patent/RS52608B/en unknown
- 2006-09-21 WO PCT/US2006/036928 patent/WO2007038243A1/en active Application Filing
- 2006-09-21 KR KR1020087009709A patent/KR101309605B1/ko not_active IP Right Cessation
- 2006-09-21 DK DK06815150.5T patent/DK1940387T3/da active
- 2006-09-21 PT PT68151505T patent/PT1940387E/pt unknown
- 2006-09-21 CA CA2623350A patent/CA2623350C/en not_active Expired - Fee Related
-
2008
- 2008-03-20 IL IL190325A patent/IL190325A/en not_active IP Right Cessation
- 2008-12-29 HK HK08114045.8A patent/HK1119953A1/xx not_active IP Right Cessation
-
2013
- 2013-01-02 HR HRP20130001TT patent/HRP20130001T1/hr unknown
Non-Patent Citations (2)
| Title |
|---|
| DEVINE et al. Tetrahedron, 1997, 53 (20), 6739-6746 * |
| SHI et al. J. Med. Chem. 2005, 48, 4457-4468 * |
Also Published As
| Publication number | Publication date |
|---|---|
| RS52608B (en) | 2013-04-30 |
| CA2623350A1 (en) | 2007-04-05 |
| PT1940387E (pt) | 2012-12-17 |
| IL190325A0 (en) | 2009-09-22 |
| PL1940387T3 (pl) | 2013-02-28 |
| IL190325A (en) | 2013-04-30 |
| HRP20130001T1 (hr) | 2013-02-28 |
| EP1940387A1 (en) | 2008-07-09 |
| HK1119953A1 (en) | 2009-03-20 |
| EP1940387B1 (en) | 2012-11-28 |
| EA200800884A1 (ru) | 2008-12-30 |
| AU2006294950A1 (en) | 2007-04-05 |
| WO2007038243A1 (en) | 2007-04-05 |
| KR101309605B1 (ko) | 2013-09-17 |
| EP1940387A4 (en) | 2010-11-03 |
| BRPI0616188A2 (pt) | 2011-06-14 |
| KR20080050527A (ko) | 2008-06-05 |
| DK1940387T3 (da) | 2013-01-02 |
| ES2394973T3 (es) | 2013-02-07 |
| US7714131B2 (en) | 2010-05-11 |
| CA2623350C (en) | 2014-08-19 |
| JP2009515817A (ja) | 2009-04-16 |
| SI1940387T1 (sl) | 2013-04-30 |
| US20070072858A1 (en) | 2007-03-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TC4A | Change in name of a patent proprietor in a eurasian patent | ||
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM RU |