EA011891B1 - Способы получения соединений бензоксазолсульфонамида и их промежуточные соединения - Google Patents
Способы получения соединений бензоксазолсульфонамида и их промежуточные соединения Download PDFInfo
- Publication number
- EA011891B1 EA011891B1 EA200600699A EA200600699A EA011891B1 EA 011891 B1 EA011891 B1 EA 011891B1 EA 200600699 A EA200600699 A EA 200600699A EA 200600699 A EA200600699 A EA 200600699A EA 011891 B1 EA011891 B1 EA 011891B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- alkyl
- aryl
- formula
- group
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03103630 | 2003-09-30 | ||
| US50799603P | 2003-10-02 | 2003-10-02 | |
| PCT/EP2004/052382 WO2005030739A1 (en) | 2003-09-30 | 2004-09-30 | Methods for the preparation of benzoxazole sulfonamide compounds and intermediates thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA200600699A1 EA200600699A1 (ru) | 2006-08-25 |
| EA011891B1 true EA011891B1 (ru) | 2009-06-30 |
Family
ID=34395298
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200600699A EA011891B1 (ru) | 2003-09-30 | 2004-09-30 | Способы получения соединений бензоксазолсульфонамида и их промежуточные соединения |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US20070123574A1 (pt) |
| EP (1) | EP1670773B1 (pt) |
| JP (1) | JP4919802B2 (pt) |
| KR (1) | KR101090102B1 (pt) |
| CN (1) | CN1860107B (pt) |
| AP (1) | AP1985A (pt) |
| AT (1) | ATE353323T1 (pt) |
| AU (1) | AU2004276017B2 (pt) |
| BR (1) | BRPI0414916A (pt) |
| CA (1) | CA2537877C (pt) |
| DE (1) | DE602004004674T2 (pt) |
| DK (1) | DK1670773T3 (pt) |
| EA (1) | EA011891B1 (pt) |
| ES (1) | ES2281828T3 (pt) |
| IL (1) | IL173891A0 (pt) |
| IN (1) | IN2012DN02301A (pt) |
| MX (1) | MXPA06003575A (pt) |
| NO (1) | NO20061951L (pt) |
| NZ (1) | NZ546279A (pt) |
| PL (1) | PL1670773T3 (pt) |
| PT (1) | PT1670773E (pt) |
| SI (1) | SI1670773T1 (pt) |
| WO (1) | WO2005030739A1 (pt) |
| ZA (1) | ZA200602603B (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR053845A1 (es) * | 2005-04-15 | 2007-05-23 | Tibotec Pharm Ltd | 5-tiazolilmetil[(1s,2r)-3-[[(2-amino-6-benzoxazolil)sulfonil)](2-metilpropil)amino]-2-hidroxi-1-(fenilmetil)propil]carbamato como mejorador de farmacos metabolizados por el citocromo p450 |
| WO2011044134A1 (en) * | 2009-10-05 | 2011-04-14 | Albany Molecular Research, Inc. | Epiminocycloalkyl(b)indole derivatives as serotonin sub-type 6 (5-ht6) modulators and uses thereof |
| CA2823955A1 (en) | 2011-01-19 | 2012-07-26 | Albany Molecular Research, Inc. | Benzofuro[3,2-c] pyridines and related analogs as serotonin sub-type 6 (5-ht6) modulators for the treatment of obesity, metabolic syndrome, cognition and schizophrenia |
| WO2014194519A1 (en) | 2013-06-07 | 2014-12-11 | Merck Sharp & Dohme Corp. | Imidazole derivatives and methods of use thereof for improving pharmacokinetics of drug |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001077092A1 (en) * | 2000-04-07 | 2001-10-18 | Samsung Electronics Co., Ltd. | Sulfonamide derivative as a matrix metalloproteinase inhibitor |
| WO2002092595A1 (en) * | 2001-05-11 | 2002-11-21 | Tibotec Pharmaceuticals Ltd. | Broadspectrum 2-amino-benzoxazole sulfonamide hiv protease inhibitors |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5968942A (en) * | 1992-08-25 | 1999-10-19 | G. D. Searle & Co. | α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors |
| DE69625183T2 (de) * | 1995-03-10 | 2003-10-09 | Searle & Co | Heterocyclocarbonyl-aminosäure-hydroxyethylamino-sulfonamid inhibitoren retroviraler proteasen |
| EP0861249A1 (en) * | 1995-11-15 | 1998-09-02 | G.D. Searle & Co. | Substituted sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors |
| US6455738B1 (en) * | 2000-07-13 | 2002-09-24 | Rhodia Chimie | Process for the sulfonation of an aromatic compound |
| MXPA03007236A (es) * | 2001-02-14 | 2003-12-04 | Tibotec Pharm Ltd | 2-(amino sustituido)-benzotiazol sulfonamidas inhibidoras de proteasa de vih de amplio espectro. |
| AR037797A1 (es) * | 2001-12-12 | 2004-12-01 | Tibotec Pharm Ltd | Combinacion de inhibidores de proteasa dependientes del citocromo p450 |
| MY142238A (en) * | 2002-03-12 | 2010-11-15 | Tibotec Pharm Ltd | Broadspectrum substituted benzimidazole sulfonamide hiv protease inhibitors |
-
2004
- 2004-09-30 KR KR1020067005992A patent/KR101090102B1/ko not_active IP Right Cessation
- 2004-09-30 AU AU2004276017A patent/AU2004276017B2/en not_active Ceased
- 2004-09-30 PT PT04766869T patent/PT1670773E/pt unknown
- 2004-09-30 MX MXPA06003575A patent/MXPA06003575A/es active IP Right Grant
- 2004-09-30 CN CN2004800280971A patent/CN1860107B/zh not_active Expired - Fee Related
- 2004-09-30 DE DE602004004674T patent/DE602004004674T2/de active Active
- 2004-09-30 ES ES04766869T patent/ES2281828T3/es active Active
- 2004-09-30 SI SI200430265T patent/SI1670773T1/sl unknown
- 2004-09-30 PL PL04766869T patent/PL1670773T3/pl unknown
- 2004-09-30 IN IN2301DEN2012 patent/IN2012DN02301A/en unknown
- 2004-09-30 CA CA2537877A patent/CA2537877C/en not_active Expired - Fee Related
- 2004-09-30 EP EP04766869A patent/EP1670773B1/en active Active
- 2004-09-30 WO PCT/EP2004/052382 patent/WO2005030739A1/en active IP Right Grant
- 2004-09-30 JP JP2006530265A patent/JP4919802B2/ja not_active Expired - Fee Related
- 2004-09-30 AT AT04766869T patent/ATE353323T1/de active
- 2004-09-30 DK DK04766869T patent/DK1670773T3/da active
- 2004-09-30 BR BRPI0414916-5A patent/BRPI0414916A/pt not_active IP Right Cessation
- 2004-09-30 US US10/574,157 patent/US20070123574A1/en not_active Abandoned
- 2004-09-30 AP AP2006003603A patent/AP1985A/xx active
- 2004-09-30 NZ NZ546279A patent/NZ546279A/en not_active IP Right Cessation
- 2004-09-30 EA EA200600699A patent/EA011891B1/ru not_active IP Right Cessation
-
2006
- 2006-02-22 IL IL173891A patent/IL173891A0/en not_active IP Right Cessation
- 2006-03-29 ZA ZA200602603A patent/ZA200602603B/xx unknown
- 2006-05-02 NO NO20061951A patent/NO20061951L/no not_active Application Discontinuation
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001077092A1 (en) * | 2000-04-07 | 2001-10-18 | Samsung Electronics Co., Ltd. | Sulfonamide derivative as a matrix metalloproteinase inhibitor |
| WO2002092595A1 (en) * | 2001-05-11 | 2002-11-21 | Tibotec Pharmaceuticals Ltd. | Broadspectrum 2-amino-benzoxazole sulfonamide hiv protease inhibitors |
Also Published As
| Publication number | Publication date |
|---|---|
| NO20061951L (no) | 2006-05-02 |
| JP4919802B2 (ja) | 2012-04-18 |
| ATE353323T1 (de) | 2007-02-15 |
| IL173891A0 (en) | 2006-07-05 |
| AU2004276017A1 (en) | 2005-04-07 |
| DK1670773T3 (da) | 2007-05-29 |
| JP2007507468A (ja) | 2007-03-29 |
| KR101090102B1 (ko) | 2011-12-07 |
| CN1860107B (zh) | 2013-08-21 |
| ES2281828T3 (es) | 2007-10-01 |
| KR20060092224A (ko) | 2006-08-22 |
| AU2004276017B2 (en) | 2010-08-19 |
| EA200600699A1 (ru) | 2006-08-25 |
| US20070123574A1 (en) | 2007-05-31 |
| BRPI0414916A (pt) | 2006-11-07 |
| NZ546279A (en) | 2008-09-26 |
| IN2012DN02301A (pt) | 2015-08-14 |
| AP2006003603A0 (en) | 2006-04-30 |
| PL1670773T3 (pl) | 2007-06-29 |
| DE602004004674T2 (de) | 2007-11-22 |
| ZA200602603B (en) | 2008-05-28 |
| WO2005030739A1 (en) | 2005-04-07 |
| EP1670773B1 (en) | 2007-02-07 |
| CN1860107A (zh) | 2006-11-08 |
| CA2537877C (en) | 2015-03-17 |
| CA2537877A1 (en) | 2005-04-07 |
| EP1670773A1 (en) | 2006-06-21 |
| PT1670773E (pt) | 2007-05-31 |
| SI1670773T1 (sl) | 2007-06-30 |
| MXPA06003575A (es) | 2006-06-05 |
| AP1985A (en) | 2009-03-30 |
| DE602004004674D1 (de) | 2007-03-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KG MD TJ TM |
|
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): KZ RU |