EA011637B1 - Лечение с использованием омега-3 жирных кислот и агониста и/или антагониста ppar и их комбинированный продукт - Google Patents

Лечение с использованием омега-3 жирных кислот и агониста и/или антагониста ppar и их комбинированный продукт Download PDF

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Publication number
EA011637B1
EA011637B1 EA200701230A EA200701230A EA011637B1 EA 011637 B1 EA011637 B1 EA 011637B1 EA 200701230 A EA200701230 A EA 200701230A EA 200701230 A EA200701230 A EA 200701230A EA 011637 B1 EA011637 B1 EA 011637B1
Authority
EA
Eurasian Patent Office
Prior art keywords
fatty acids
omega
antagonist
agonist
solvent system
Prior art date
Application number
EA200701230A
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English (en)
Russian (ru)
Other versions
EA200701230A1 (ru
Inventor
Джордж Боботас
Рулоф М.Л. Ронген
Роберт А. МС Шалвиц
Original Assignee
Релайэнт Фармасьютикалз, Инк.
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Application filed by Релайэнт Фармасьютикалз, Инк. filed Critical Релайэнт Фармасьютикалз, Инк.
Publication of EA200701230A1 publication Critical patent/EA200701230A1/ru
Publication of EA011637B1 publication Critical patent/EA011637B1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
EA200701230A 2004-12-06 2005-12-05 Лечение с использованием омега-3 жирных кислот и агониста и/или антагониста ppar и их комбинированный продукт EA011637B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63312504P 2004-12-06 2004-12-06
PCT/US2005/044035 WO2006062932A2 (en) 2004-12-06 2005-12-05 Treatment with omega-3 fatty acids and ppar agonist and/or antagonist and a combination product thereof

Publications (2)

Publication Number Publication Date
EA200701230A1 EA200701230A1 (ru) 2007-12-28
EA011637B1 true EA011637B1 (ru) 2009-04-28

Family

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EA200701230A EA011637B1 (ru) 2004-12-06 2005-12-05 Лечение с использованием омега-3 жирных кислот и агониста и/или антагониста ppar и их комбинированный продукт

Country Status (12)

Country Link
US (1) US20060211749A1 (https=)
EP (1) EP1835901A2 (https=)
JP (1) JP2008524120A (https=)
KR (1) KR20070094619A (https=)
CN (2) CN101098690A (https=)
AU (1) AU2005314196A1 (https=)
BR (1) BRPI0518425A2 (https=)
CA (1) CA2589655A1 (https=)
EA (1) EA011637B1 (https=)
MX (1) MX2007006708A (https=)
NO (1) NO20073458L (https=)
WO (1) WO2006062932A2 (https=)

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WO2017120383A1 (en) * 2016-01-06 2017-07-13 Kang Jing X Compositions and methods for sustained low blood glucose levels

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Publication number Priority date Publication date Assignee Title
WO2017120383A1 (en) * 2016-01-06 2017-07-13 Kang Jing X Compositions and methods for sustained low blood glucose levels

Also Published As

Publication number Publication date
WO2006062932A3 (en) 2006-09-28
KR20070094619A (ko) 2007-09-20
EA200701230A1 (ru) 2007-12-28
JP2008524120A (ja) 2008-07-10
WO2006062932A2 (en) 2006-06-15
CN101098690A (zh) 2008-01-02
NO20073458L (no) 2007-09-05
BRPI0518425A2 (pt) 2008-11-25
CA2589655A1 (en) 2006-06-15
CN101098688A (zh) 2008-01-02
US20060211749A1 (en) 2006-09-21
MX2007006708A (es) 2008-01-16
EP1835901A2 (en) 2007-09-26
AU2005314196A1 (en) 2006-06-15

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