EA005157B1 - Методы и составы для лечения сердечной недостаточности и вентрикулярной коррекции путем доставки in vivo ангиогенных трансгенов - Google Patents

Методы и составы для лечения сердечной недостаточности и вентрикулярной коррекции путем доставки in vivo ангиогенных трансгенов Download PDF

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Publication number
EA005157B1
EA005157B1 EA199901002A EA199901002A EA005157B1 EA 005157 B1 EA005157 B1 EA 005157B1 EA 199901002 A EA199901002 A EA 199901002A EA 199901002 A EA199901002 A EA 199901002A EA 005157 B1 EA005157 B1 EA 005157B1
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EA
Eurasian Patent Office
Prior art keywords
vector
angiogenic protein
peptide
promoter
fgf
Prior art date
Application number
EA199901002A
Other languages
English (en)
Russian (ru)
Other versions
EA199901002A1 (ru
Inventor
Х. Кёрк Хэммонд
Тамсин Л. Келли
Original Assignee
Те Риджентс Оф Те Юниверсити Оф Калифорния
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Application filed by Те Риджентс Оф Те Юниверсити Оф Калифорния filed Critical Те Риджентс Оф Те Юниверсити Оф Калифорния
Publication of EA199901002A1 publication Critical patent/EA199901002A1/ru
Publication of EA005157B1 publication Critical patent/EA005157B1/ru

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1825Fibroblast growth factor [FGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1858Platelet-derived growth factor [PDGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1858Platelet-derived growth factor [PDGF]
    • A61K38/1866Vascular endothelial growth factor [VEGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/30Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EA199901002A 1997-05-06 1998-04-30 Методы и составы для лечения сердечной недостаточности и вентрикулярной коррекции путем доставки in vivo ангиогенных трансгенов EA005157B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85277997A 1997-05-06 1997-05-06
PCT/US1998/008848 WO1998050079A2 (fr) 1997-05-06 1998-04-30 Techniques et compositions destinees au traitement d'une insuffisance cardiaque et du remodelage ventriculaire par apport in vivo de transgenes angiogeniques

Publications (2)

Publication Number Publication Date
EA199901002A1 EA199901002A1 (ru) 2000-08-28
EA005157B1 true EA005157B1 (ru) 2004-12-30

Family

ID=25314196

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199901002A EA005157B1 (ru) 1997-05-06 1998-04-30 Методы и составы для лечения сердечной недостаточности и вентрикулярной коррекции путем доставки in vivo ангиогенных трансгенов

Country Status (8)

Country Link
EP (1) EP0980428A2 (fr)
JP (1) JP2002515065A (fr)
KR (2) KR20070005030A (fr)
CN (1) CN1267331A (fr)
AU (1) AU7173598A (fr)
CA (1) CA2289600C (fr)
EA (1) EA005157B1 (fr)
WO (1) WO1998050079A2 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2329934A1 (fr) * 1998-05-30 1999-12-09 Collateral Therapeutics, Inc. Procedes de modification du phenotype de la cellule cardiaque
DE19915485A1 (de) 1999-04-07 2000-10-19 Hugo A Katus Therapie der Herzinsuffizienz
NZ546670A (en) * 1999-11-05 2009-02-28 Univ California Techniques and compositions for treating cardiovascular disease by in vivo gene delivery
AU2002216751A1 (en) * 2000-06-30 2002-01-14 Collateral Therapeutics, Inc. Dual recombinant gene therapy compositions and methods of use
KR100562824B1 (ko) 2002-03-20 2006-03-23 주식회사 바이로메드 유전자 발현효율이 높으며 간세포 성장인자의 두 가지이형체를 동시에 발현하는 하이브리드 간세포 성장인자유전자
US7875017B2 (en) 2007-04-11 2011-01-25 Henry Ford Health System Cardiac repair, resizing and reshaping using the venous system of the heart
EP2244740A1 (fr) 2008-02-19 2010-11-03 Celladon Corporation Compositions pour un captage amélioré de vecteurs viraux dans le myocarde
MX2010010993A (es) 2008-04-09 2010-11-05 Viromed Co Ltd Formulaciones liofilizadas de adn para expresion mejorada de adn de plasmido.
CN102076352B (zh) 2008-05-02 2016-06-15 西安大略大学 与血管有关的fgf-9和它的用途
EP3311830A1 (fr) * 2012-02-14 2018-04-25 The Regents of The University of California Administration systémique et expression régulée des gènes à action paracrine pour les maladies cardiovasculaires et autres états
CN105682676B (zh) 2013-10-22 2020-10-23 赫利世弥斯株式会社 利用肝细胞生长因子的两种以上的异构体的肌萎缩性侧索硬化症预防或治疗用组合物
AU2019305221A1 (en) 2018-07-19 2021-02-18 Helixmith Co., Ltd. Lyophilized pharmaceutical compositions for naked DNA gene therapy
CN109517807A (zh) * 2018-11-20 2019-03-26 暨南大学 一种心脏血管靶向的噬菌体载体及其用途
EP3942018A4 (fr) * 2019-03-17 2022-12-07 Baylor College of Medicine Reprogrammation directe de fibroblastes cardiaques en cardiomyocytes à l'aide d'une stratégie de transdifférenciation de cellules endothéliales

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0760682A4 (fr) * 1995-02-28 1998-09-09 Univ California Therapie angiogenique par transfert de genes

Also Published As

Publication number Publication date
KR20070005030A (ko) 2007-01-09
KR20010012313A (ko) 2001-02-15
CN1267331A (zh) 2000-09-20
CA2289600A1 (fr) 1998-11-12
JP2002515065A (ja) 2002-05-21
AU7173598A (en) 1998-11-27
EP0980428A2 (fr) 2000-02-23
CA2289600C (fr) 2010-06-29
EA199901002A1 (ru) 2000-08-28
WO1998050079A3 (fr) 1999-02-04
WO1998050079A2 (fr) 1998-11-12

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU