EA001456B1 - Твердые смеси циклодекстринов, полученные путем экструзии в расплаве - Google Patents

Твердые смеси циклодекстринов, полученные путем экструзии в расплаве Download PDF

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Publication number
EA001456B1
EA001456B1 EA199800347A EA199800347A EA001456B1 EA 001456 B1 EA001456 B1 EA 001456B1 EA 199800347 A EA199800347 A EA 199800347A EA 199800347 A EA199800347 A EA 199800347A EA 001456 B1 EA001456 B1 EA 001456B1
Authority
EA
Eurasian Patent Office
Prior art keywords
mixture
cyclodextrin
melt
cyclodextrins
active ingredient
Prior art date
Application number
EA199800347A
Other languages
English (en)
Russian (ru)
Other versions
EA199800347A1 (ru
Inventor
Льевен Эльвир Колетт Бар
Жозеф Петерс
Гер Веррек
Original Assignee
Жансен Фармасетика Н.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Жансен Фармасетика Н.В. filed Critical Жансен Фармасетика Н.В.
Priority claimed from PCT/EP1996/005118 external-priority patent/WO1997018839A1/en
Publication of EA199800347A1 publication Critical patent/EA199800347A1/ru
Publication of EA001456B1 publication Critical patent/EA001456B1/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates

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  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
EA199800347A 1995-11-23 1996-11-20 Твердые смеси циклодекстринов, полученные путем экструзии в расплаве EA001456B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP95203219 1995-11-23
PCT/EP1996/005118 WO1997018839A1 (en) 1995-11-23 1996-11-20 Solid mixtures of cyclodextrins prepared via melt-extrusion

Publications (2)

Publication Number Publication Date
EA199800347A1 EA199800347A1 (ru) 1998-10-29
EA001456B1 true EA001456B1 (ru) 2001-04-23

Family

ID=8220858

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199800347A EA001456B1 (ru) 1995-11-23 1996-11-20 Твердые смеси циклодекстринов, полученные путем экструзии в расплаве

Country Status (4)

Country Link
KR (1) KR100441109B1 (ko)
CA (1) CA2232135A1 (ko)
EA (1) EA001456B1 (ko)
TW (1) TW377357B (ko)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5009900A (en) * 1989-10-02 1991-04-23 Nabisco Brands, Inc. Glassy matrices containing volatile and/or labile components, and processes for preparation and use thereof
WO1994011031A1 (en) * 1992-11-10 1994-05-26 Nippon Shinyaku Co., Ltd. Enclosure compound manufacturing method
FR2705677A1 (fr) * 1993-05-28 1994-12-02 Roquette Freres Micro-granules obtenus par extrusion-sphéronisation contenant une cyclodextrine.
EP0665009A1 (en) * 1992-10-14 1995-08-02 Nippon Shinyaku Company, Limited Crystalline condition dislocating method

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5009900A (en) * 1989-10-02 1991-04-23 Nabisco Brands, Inc. Glassy matrices containing volatile and/or labile components, and processes for preparation and use thereof
EP0665009A1 (en) * 1992-10-14 1995-08-02 Nippon Shinyaku Company, Limited Crystalline condition dislocating method
WO1994011031A1 (en) * 1992-11-10 1994-05-26 Nippon Shinyaku Co., Ltd. Enclosure compound manufacturing method
FR2705677A1 (fr) * 1993-05-28 1994-12-02 Roquette Freres Micro-granules obtenus par extrusion-sphéronisation contenant une cyclodextrine.

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
J. ANTIMICROB. CHEMOTHER., 1993, VOL. 32, NO. 3, PAGE(S) 459-463, XP002002174 HOSTETLER J.S. ET AL: "Effect of hydroxypropyl-beta-cyclodextrin on efficacy of oral itraconazole in disseminated murine cryptococcosis" cited in the application see abstract * paragraph Results * *
J. PHARM. PHARMACOL., VOL. 44, NO. 2, PAGE(S) 73-8, 1992, XP002002172 UEKAMA, KANETO ET AL: "Inhibitory effect of 2-hydroxypropyl-.beta.-cyclodextrin on crystal growth of nifedipine during storage: superior dissolution and oral bioavailability compared with poly(vinylpyrrolidone) K-30" cited in the application * paragraph Materials and methods * see figures *
JPN. J. MED. MYCOL., 1994, VOL. 35, NO. 3, PAGE(S) 263-267, XP002002175 MIKAMI Y. ET AL: "Effect of carrier solvents on the efficacy of oral itraconazole therapy in aspergillosis in; mice" cited in the application, see abstract, see figures *
PHARM. RES., VOL. 11, NO. 12, PAGE(S) 1766-70, 1994, XP002002176 HIRAYAMA, FUMITOSHI ET AL: "Effect of 2-hydroxypropyl-.beta.-cyclodextrin on crystallization and polymorphic transition of nifedipine in solid state" cited in the application, see abstract * paragraph Results and discussion * *
PHARM. WEEKBL. SCI. ED., 1988, VOL. 10, NO. 2, PAGE(S) 80-85, XP002002173 VAN DOORNE H. ET AL: "Formation and antimicrobial activity of complexes of beta-cyclodextrin and some antimycotic imidazole derivatives" cited in the application see abstract * paragraph Results and discussion * see page 85, left-hand column *

Also Published As

Publication number Publication date
EA199800347A1 (ru) 1998-10-29
TW377357B (en) 1999-12-21
KR100441109B1 (ko) 2004-10-06
CA2232135A1 (en) 1997-05-29
KR19990067009A (ko) 1999-08-16

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