TW377357B - Process for preparing solid mixtures comprising cyclodextrins and active ingredients by melt-extrusion - Google Patents

Process for preparing solid mixtures comprising cyclodextrins and active ingredients by melt-extrusion

Info

Publication number
TW377357B
TW377357B TW085114096A TW85114096A TW377357B TW 377357 B TW377357 B TW 377357B TW 085114096 A TW085114096 A TW 085114096A TW 85114096 A TW85114096 A TW 85114096A TW 377357 B TW377357 B TW 377357B
Authority
TW
Taiwan
Prior art keywords
cyclodextrins
melt
extrusion
active ingredients
preparing solid
Prior art date
Application number
TW085114096A
Other languages
Chinese (zh)
Inventor
Lieven E C Baert
Jozef Peeters
Geert Verreck
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of TW377357B publication Critical patent/TW377357B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

Process for preparing a solid mixture comprising one or more cyclodextrins and an insoluble active ingredient characterized in that said process comprises a melt-extrusion step, wherein the active ingredient is embedded into the cyclodextrin carrier.
TW085114096A 1995-11-23 1996-11-18 Process for preparing solid mixtures comprising cyclodextrins and active ingredients by melt-extrusion TW377357B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP95203219 1995-11-23

Publications (1)

Publication Number Publication Date
TW377357B true TW377357B (en) 1999-12-21

Family

ID=8220858

Family Applications (1)

Application Number Title Priority Date Filing Date
TW085114096A TW377357B (en) 1995-11-23 1996-11-18 Process for preparing solid mixtures comprising cyclodextrins and active ingredients by melt-extrusion

Country Status (4)

Country Link
KR (1) KR100441109B1 (en)
CA (1) CA2232135A1 (en)
EA (1) EA001456B1 (en)
TW (1) TW377357B (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5009900A (en) * 1989-10-02 1991-04-23 Nabisco Brands, Inc. Glassy matrices containing volatile and/or labile components, and processes for preparation and use thereof
DE69327877T2 (en) * 1992-10-14 2000-10-05 Nippon Shinyaku Co Ltd METHOD FOR SHIFTING A CRYSTAL CONDITION
WO1994011031A1 (en) * 1992-11-10 1994-05-26 Nippon Shinyaku Co., Ltd. Enclosure compound manufacturing method
FR2705677B1 (en) * 1993-05-28 1995-08-11 Roquette Freres Micro-granules obtained by extrusion-spheronization containing a cyclodextrin.

Also Published As

Publication number Publication date
EA001456B1 (en) 2001-04-23
EA199800347A1 (en) 1998-10-29
KR100441109B1 (en) 2004-10-06
CA2232135A1 (en) 1997-05-29
KR19990067009A (en) 1999-08-16

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