EA199800347A1 - SOLID CYCLODEXTRIN MIXTURES OBTAINED BY EXTRUSION IN MELT - Google Patents

SOLID CYCLODEXTRIN MIXTURES OBTAINED BY EXTRUSION IN MELT

Info

Publication number
EA199800347A1
EA199800347A1 EA199800347A EA199800347A EA199800347A1 EA 199800347 A1 EA199800347 A1 EA 199800347A1 EA 199800347 A EA199800347 A EA 199800347A EA 199800347 A EA199800347 A EA 199800347A EA 199800347 A1 EA199800347 A1 EA 199800347A1
Authority
EA
Eurasian Patent Office
Prior art keywords
melt
extrusion
mixtures obtained
solid cyclodextrin
cyclodextrin mixtures
Prior art date
Application number
EA199800347A
Other languages
Russian (ru)
Other versions
EA001456B1 (en
Inventor
Льевен Эльвир Колетт Бар
Жозеф Петерс
Гер Веррек
Original Assignee
Жансен Фармасетика Н.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Жансен Фармасетика Н.В. filed Critical Жансен Фармасетика Н.В.
Priority claimed from PCT/EP1996/005118 external-priority patent/WO1997018839A1/en
Publication of EA199800347A1 publication Critical patent/EA199800347A1/en
Publication of EA001456B1 publication Critical patent/EA001456B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

Способ получения твердой смеси, содержащей один или несколько циклодекстринов и нерастворимый активный ингредиент, отличающийся тем, что указанный способ включает стадию экструзии в расплаве, на которой активный ингредиент вводится в циклодекстриновый носитель.Международная заявка была опубликована вместе с отчетом о международном поиске.A method of obtaining a solid mixture containing one or more cyclodextrins and an insoluble active ingredient, characterized in that the method includes a melt-extrusion step, in which the active ingredient is introduced into a cyclodextrin carrier.

EA199800347A 1995-11-23 1996-11-20 Solid mixtures of cyclodextrins prepared via melt-extrusion EA001456B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP95203219 1995-11-23
PCT/EP1996/005118 WO1997018839A1 (en) 1995-11-23 1996-11-20 Solid mixtures of cyclodextrins prepared via melt-extrusion

Publications (2)

Publication Number Publication Date
EA199800347A1 true EA199800347A1 (en) 1998-10-29
EA001456B1 EA001456B1 (en) 2001-04-23

Family

ID=8220858

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199800347A EA001456B1 (en) 1995-11-23 1996-11-20 Solid mixtures of cyclodextrins prepared via melt-extrusion

Country Status (4)

Country Link
KR (1) KR100441109B1 (en)
CA (1) CA2232135A1 (en)
EA (1) EA001456B1 (en)
TW (1) TW377357B (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5009900A (en) * 1989-10-02 1991-04-23 Nabisco Brands, Inc. Glassy matrices containing volatile and/or labile components, and processes for preparation and use thereof
JP2616251B2 (en) * 1992-10-14 1997-06-04 日本新薬株式会社 Crystal state transition method
WO1994011031A1 (en) * 1992-11-10 1994-05-26 Nippon Shinyaku Co., Ltd. Enclosure compound manufacturing method
FR2705677B1 (en) * 1993-05-28 1995-08-11 Roquette Freres Micro-granules obtained by extrusion-spheronization containing a cyclodextrin.

Also Published As

Publication number Publication date
KR19990067009A (en) 1999-08-16
TW377357B (en) 1999-12-21
CA2232135A1 (en) 1997-05-29
EA001456B1 (en) 2001-04-23
KR100441109B1 (en) 2004-10-06

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