DOP2013000016A - Formas cristalinas del dimetoxi-docetaxel y sus procedimientos de preparacion - Google Patents

Formas cristalinas del dimetoxi-docetaxel y sus procedimientos de preparacion

Info

Publication number
DOP2013000016A
DOP2013000016A DO2013000016A DO2013000016A DOP2013000016A DO P2013000016 A DOP2013000016 A DO P2013000016A DO 2013000016 A DO2013000016 A DO 2013000016A DO 2013000016 A DO2013000016 A DO 2013000016A DO P2013000016 A DOP2013000016 A DO P2013000016A
Authority
DO
Dominican Republic
Prior art keywords
docetaxel
dimetoxi
crystal forms
preparation procedures
solvates
Prior art date
Application number
DO2013000016A
Other languages
English (en)
Inventor
Patricia Rortais
Pascal Billot
Marielle Dufraigne
Hagit Elmaleh
Alexandre Giuliani
Fabrice Mangin
Lionel Zaske
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39712334&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DOP2013000016(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of DOP2013000016A publication Critical patent/DOP2013000016A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Abstract

Formas anhidras, solvatos y hetero-solvatos etanólicos, hidratos de dimetoxi5 docetaxel o (2R,3 S)-3-terc-butoxicarbonilamino-2-hidroxi-3-feni I-propionato de 4-acetoxi-2 Z -benzoiloxi-5 Z ,20-epoxi-1 -hidroxi-7 Z , 1 O Z -dimetoxi-9-oxo-tax-1 1 -en13Z-ilo y su preparación.
DO2013000016A 2008-01-17 2013-01-15 Formas cristalinas del dimetoxi-docetaxel y sus procedimientos de preparacion DOP2013000016A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0800243A FR2926551A1 (fr) 2008-01-17 2008-01-17 Formes cristallines du dimethoxy docetaxel et leurs procedes de preparation

Publications (1)

Publication Number Publication Date
DOP2013000016A true DOP2013000016A (es) 2013-06-15

Family

ID=39712334

Family Applications (3)

Application Number Title Priority Date Filing Date
DO2010000211A DOP2010000211A (es) 2008-01-17 2010-07-07 Formas cristalinas del dimetoxi-docetaxel y sus procedimientos de preparacion
DO2013000016A DOP2013000016A (es) 2008-01-17 2013-01-15 Formas cristalinas del dimetoxi-docetaxel y sus procedimientos de preparacion
DO2013000212A DOP2013000212A (es) 2008-01-17 2013-09-25 Formas cristalinas del dimetoxi-docetaxel y sus procedimientos de preparacion

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DO2010000211A DOP2010000211A (es) 2008-01-17 2010-07-07 Formas cristalinas del dimetoxi-docetaxel y sus procedimientos de preparacion

Family Applications After (1)

Application Number Title Priority Date Filing Date
DO2013000212A DOP2013000212A (es) 2008-01-17 2013-09-25 Formas cristalinas del dimetoxi-docetaxel y sus procedimientos de preparacion

Country Status (42)

Country Link
US (5) US8378128B2 (es)
EP (2) EP2247582B1 (es)
JP (3) JP5932219B2 (es)
KR (3) KR20150042303A (es)
CN (3) CN104130220A (es)
AR (1) AR070175A1 (es)
AU (1) AU2009227081B2 (es)
BR (1) BRPI0906518A2 (es)
CA (1) CA2712373C (es)
CL (1) CL2009000094A1 (es)
CO (1) CO6351784A2 (es)
CR (1) CR11532A (es)
CY (1) CY1119129T1 (es)
DK (1) DK2247582T3 (es)
DO (3) DOP2010000211A (es)
EA (1) EA017670B1 (es)
EC (1) ECSP10010324A (es)
ES (1) ES2606228T3 (es)
FR (1) FR2926551A1 (es)
HK (1) HK1150603A1 (es)
HN (1) HN2010001435A (es)
HR (1) HRP20161655T1 (es)
HU (1) HUE032150T2 (es)
IL (2) IL207031A (es)
LT (1) LT2247582T (es)
MA (1) MA32086B1 (es)
ME (2) ME02694B (es)
MX (1) MX2010007840A (es)
MY (1) MY159362A (es)
NI (4) NI201001031A (es)
NZ (3) NZ586829A (es)
PL (1) PL2247582T3 (es)
PT (1) PT2247582T (es)
RS (1) RS55519B1 (es)
SG (1) SG179446A1 (es)
SI (1) SI2247582T1 (es)
TN (1) TN2010000284A1 (es)
TW (3) TW201444814A (es)
UA (1) UA105896C2 (es)
UY (1) UY31602A1 (es)
WO (1) WO2009115655A2 (es)
ZA (1) ZA201105206B (es)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2493466T (pt) 2009-10-29 2021-03-29 Sanofi Mature Ip Nova utilização antifúngica do cabazitaxel
ES2621800T3 (es) 2011-04-12 2017-07-05 Teva Pharmaceuticals International Gmbh Formas de estado sólido de cabazitaxel y procesos de preparación de las mismas
TWI526437B (zh) 2011-09-09 2016-03-21 台灣神隆股份有限公司 卡巴他賽之結晶型
WO2013069027A1 (en) 2011-09-26 2013-05-16 Fresenius Kabi Oncology Ltd. Processes for the preparation of cabazitaxel involving c(7) -oh and c(13) -oh silylation or just c(7) -oh silylation
CN102503913B (zh) * 2011-10-20 2014-03-26 江苏红豆杉生物科技股份有限公司 直接用于x射线单晶衍射分析的二甲氧基紫杉烷类化合物单晶晶体的制备方法
CN103874692A (zh) 2011-11-01 2014-06-18 费森尤斯卡比肿瘤学有限公司 卡巴他赛的无定形形式和用于其制备的方法
DE112012004944T5 (de) * 2011-11-28 2014-12-11 Fresenius Kabi Oncology Ltd. Kristalline Formen von Cabazitaxel und deren Herstellungsverfahren
EP2791122B1 (en) 2011-12-13 2019-01-23 Aventis Pharma S.A. Crystalline form of cabazitaxel and process for preparing the same
US9403785B2 (en) 2012-01-03 2016-08-02 Shilpa Medicare Limited Process for preparing amorphous cabazitaxel
US9394266B2 (en) 2012-03-08 2016-07-19 IVAX International GmbH Solid state forms of cabazitaxel and processes for preparation thereof
CN102675257B (zh) * 2012-05-10 2014-07-02 上海金和生物技术有限公司 一种卡巴他赛晶体及其制备方法
CN102746258B (zh) 2012-07-25 2015-02-04 重庆泰濠制药有限公司 卡巴他赛的结晶形式及其制备方法
WO2014022237A1 (en) 2012-07-31 2014-02-06 Yung Shin Pharm. Ind. Co., Ltd. Amorphous cabazitaxel
TWI599373B (zh) 2012-08-15 2017-09-21 永信藥品工業股份有限公司 卡巴利他索（ｃａｂａｚｉｔａｘｅｌ）之穩定醫藥調配物
CN103664836B (zh) * 2012-09-20 2016-04-20 齐鲁制药有限公司 7β,10β-二甲氧基多西紫杉醇氘代丙酮合物的晶型A及其制备方法
CN102898406B (zh) * 2012-11-02 2014-12-03 上海金和生物技术有限公司 一种卡巴他赛晶体及其制备方法
CN103058960B (zh) * 2012-12-12 2014-12-10 江苏奥赛康药业股份有限公司 卡巴他赛多晶型形式及其制备方法
KR101429543B1 (ko) * 2012-12-13 2014-08-14 주식회사 삼양바이오팜 카바지탁셀의 신규 결정형 및 그 제조방법
EP2743264A1 (en) 2012-12-13 2014-06-18 INDENA S.p.A. New crystalline form of cabazitaxel, process for the preparation and pharmaceutical compositions thereof
CN103910698B (zh) * 2012-12-30 2016-01-20 上海医药工业研究院 卡巴他赛丙酮合物及其结晶
CN103910697B (zh) * 2012-12-30 2016-08-03 上海医药工业研究院 卡巴他赛乙酸合物及其结晶
CN103910696B (zh) * 2012-12-30 2016-01-20 上海医药工业研究院 卡巴他赛异丙醚合物及其结晶
AU2013368947B2 (en) * 2012-12-31 2016-11-24 Shilpa Medicare Limited Process for preparing amorphous Cabazitaxel
WO2014115168A2 (en) * 2013-01-23 2014-07-31 Leiutis Pharmaceuticals Private Limited Novel solvate forms of cabazitaxel and process for preparation thereof
WO2014128728A2 (en) * 2013-02-25 2014-08-28 Laurus Labs Private Limited Solid forms of cabazitaxel and processes for preparation thereof
EP2815749A1 (en) 2013-06-20 2014-12-24 IP Gesellschaft für Management mbH Solid form of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione having specified X-ray diffraction pattern
WO2015000165A1 (zh) * 2013-07-04 2015-01-08 北京新天宇科技开发有限公司 二甲氧基多西紫杉醇一丙酮化物的稳定转化物及其结晶形式、以及它们的制备方法
CN103450119B (zh) * 2013-09-24 2015-06-17 天津炜捷制药有限公司 一种卡巴他赛晶型w及其制备方法
EP2865674A1 (en) 2013-10-23 2015-04-29 INDENA S.p.A. Crystalline solvate forms of Cabazitaxel
EP2865675A1 (en) 2013-10-23 2015-04-29 INDENA S.p.A. A crystalline anhydrous form of Cabazitaxel, process for the preparation and pharmaceutical compositions thereof
CN103601704B (zh) * 2013-11-22 2015-05-06 石家庄智恒医药科技有限公司 无定形卡巴他赛的制备
CN108558969A (zh) * 2014-03-28 2018-09-21 江苏天士力帝益药业有限公司 吡唑衍生物的多晶型物
US10188626B2 (en) 2015-11-03 2019-01-29 Cipla Limited Stabilized cabazitaxel formulations
WO2020249507A1 (en) 2019-06-11 2020-12-17 Indena S.P.A. Anhydrous crystalline form of cabazitaxel, a process for its preparation and pharmaceutical compositions containing it

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2163837C (en) * 1994-12-13 1999-07-20 Robert K. Perrone Crystalline paclitaxel hydrates
US5847170A (en) * 1995-03-27 1998-12-08 Rhone-Poulenc Rorer, S.A. Taxoids, their preparation and pharmaceutical compositions containing them
MA23823A1 (fr) * 1995-03-27 1996-10-01 Aventis Pharma Sa Nouveaux taxoides, leur preparation et les compositions qui les contiennent
FR2745814B1 (fr) * 1996-03-06 1998-04-03 Rhone Poulenc Rorer Sa Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2771092B1 (fr) * 1997-11-18 1999-12-17 Rhone Poulenc Rorer Sa Procede de preparation de derives de la classe des taxoides
US6346543B1 (en) * 1998-08-17 2002-02-12 Aventis Pharma S.A. Use of a taxoid to treat abnormal cell proliferation in the brain
MXPA04005038A (es) * 2001-11-30 2004-08-11 Bristol Myers Squibb Co Solvatos de paclitaxel.
FR2859996B1 (fr) * 2003-09-19 2006-02-03 Aventis Pharma Sa Solvat acetonique du dimethoxy docetaxel et son procede de preparation
WO2007044950A2 (en) * 2005-10-12 2007-04-19 Sicor, Inc. Crystalline forms of docetaxel and processes for their preparation
TWI394765B (zh) * 2008-12-12 2013-05-01 Ind Tech Res Inst 難燃水性聚胺基甲酸酯分散液
PT2493466T (pt) 2009-10-29 2021-03-29 Sanofi Mature Ip Nova utilização antifúngica do cabazitaxel
TWI526437B (zh) 2011-09-09 2016-03-21 台灣神隆股份有限公司 卡巴他賽之結晶型
DE112012004944T5 (de) 2011-11-28 2014-12-11 Fresenius Kabi Oncology Ltd. Kristalline Formen von Cabazitaxel und deren Herstellungsverfahren
EP2791122B1 (en) 2011-12-13 2019-01-23 Aventis Pharma S.A. Crystalline form of cabazitaxel and process for preparing the same

Also Published As

Publication number Publication date
SI2247582T1 (sl) 2017-03-31
EP2247582B1 (fr) 2016-09-07
RS55519B1 (sr) 2017-05-31
BRPI0906518A2 (pt) 2015-07-14
EA017670B1 (ru) 2013-02-28
KR20150042302A (ko) 2015-04-20
MA32086B1 (fr) 2011-02-01
NI201000103A (es) 2011-04-26
NI201001033A (es) 2011-04-26
HUE032150T2 (en) 2017-08-28
DOP2013000212A (es) 2014-01-31
CA2712373C (fr) 2016-06-14
US20110144362A1 (en) 2011-06-16
FR2926551A1 (fr) 2009-07-24
US20130178639A1 (en) 2013-07-11
CN104130221A (zh) 2014-11-05
JP2014074054A (ja) 2014-04-24
HN2010001435A (es) 2014-02-03
CA2712373A1 (fr) 2009-09-24
KR20150042303A (ko) 2015-04-20
US8846959B2 (en) 2014-09-30
MY159362A (en) 2016-12-30
DOP2010000211A (es) 2010-07-31
IL207031A (en) 2017-11-30
TW201444814A (zh) 2014-12-01
NZ603797A (en) 2013-05-31
ME02694B (me) 2017-10-20
US8378128B2 (en) 2013-02-19
CY1119129T1 (el) 2018-02-14
ME01009B (me) 2012-10-20
PL2247582T3 (pl) 2017-04-28
TW200944510A (en) 2009-11-01
KR20100103614A (ko) 2010-09-27
DK2247582T3 (da) 2017-01-02
US20140350272A1 (en) 2014-11-27
UA105896C2 (uk) 2014-07-10
SG179446A1 (en) 2012-04-27
CN101918385B (zh) 2014-07-02
NZ586829A (en) 2012-05-25
CN101918385A (zh) 2010-12-15
AU2009227081B2 (en) 2013-11-14
EP2719694A1 (fr) 2014-04-16
WO2009115655A3 (fr) 2010-04-01
TN2010000284A1 (fr) 2011-11-11
CN104130220A (zh) 2014-11-05
CL2009000094A1 (es) 2010-02-12
CR11532A (es) 2010-11-22
MX2010007840A (es) 2010-08-04
TWI477492B (zh) 2015-03-21
JP2011509980A (ja) 2011-03-31
JP5932219B2 (ja) 2016-06-08
AU2009227081A1 (en) 2009-09-24
LT2247582T (lt) 2017-01-25
NI201001031A (es) 2011-04-26
NI201001032A (es) 2011-04-26
US10160739B2 (en) 2018-12-25
US20180002302A1 (en) 2018-01-04
UY31602A1 (es) 2009-08-31
ZA201105206B (en) 2013-05-29
WO2009115655A2 (fr) 2009-09-24
EA201070856A1 (ru) 2011-02-28
EP2247582A2 (fr) 2010-11-10
HRP20161655T1 (hr) 2017-01-27
NZ598289A (en) 2013-06-28
PT2247582T (pt) 2016-11-16
IL229239A0 (en) 2013-12-31
AR070175A1 (es) 2010-03-17
JP2015163626A (ja) 2015-09-10
IL207031A0 (en) 2010-12-30
ES2606228T3 (es) 2017-03-23
TW201444813A (zh) 2014-12-01
CO6351784A2 (es) 2011-12-20
ECSP10010324A (es) 2010-08-31
HK1150603A1 (en) 2012-01-06
US20190144406A1 (en) 2019-05-16

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