DOP2010000389A - Derivados de benzoxazinona que actuan como agonistas de receptores adrenergicos b2 para el tratamiento de trastornos respiratorios - Google Patents

Derivados de benzoxazinona que actuan como agonistas de receptores adrenergicos b2 para el tratamiento de trastornos respiratorios

Info

Publication number
DOP2010000389A
DOP2010000389A DO2010000389A DO2010000389A DOP2010000389A DO P2010000389 A DOP2010000389 A DO P2010000389A DO 2010000389 A DO2010000389 A DO 2010000389A DO 2010000389 A DO2010000389 A DO 2010000389A DO P2010000389 A DOP2010000389 A DO P2010000389A
Authority
DO
Dominican Republic
Prior art keywords
treatment
respiratory disorders
derivatives acting
benzoxazinone derivatives
adrenergic
Prior art date
Application number
DO2010000389A
Other languages
English (en)
Spanish (es)
Inventor
Roger Victor Bonnert
Stephen Connolly
Anthony Ronald Cook
Richard Evans
Piotr Raubo
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of DOP2010000389A publication Critical patent/DOP2010000389A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
DO2010000389A 2008-06-18 2010-12-17 Derivados de benzoxazinona que actuan como agonistas de receptores adrenergicos b2 para el tratamiento de trastornos respiratorios DOP2010000389A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7342008P 2008-06-18 2008-06-18

Publications (1)

Publication Number Publication Date
DOP2010000389A true DOP2010000389A (es) 2011-01-15

Family

ID=41434296

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2010000389A DOP2010000389A (es) 2008-06-18 2010-12-17 Derivados de benzoxazinona que actuan como agonistas de receptores adrenergicos b2 para el tratamiento de trastornos respiratorios

Country Status (21)

Country Link
US (1) US8017602B2 (enExample)
EP (1) EP2303873A4 (enExample)
JP (1) JP2011524896A (enExample)
KR (1) KR20110017456A (enExample)
CN (1) CN102124003A (enExample)
AR (1) AR072189A1 (enExample)
AU (1) AU2009260899B2 (enExample)
BR (1) BRPI0915428A2 (enExample)
CA (1) CA2726746A1 (enExample)
CL (1) CL2010001459A1 (enExample)
CO (1) CO6321269A2 (enExample)
CR (1) CR11856A (enExample)
DO (1) DOP2010000389A (enExample)
EA (1) EA201001747A1 (enExample)
EC (1) ECSP10010694A (enExample)
IL (1) IL209731A0 (enExample)
MX (1) MX2010013477A (enExample)
TW (1) TW201002696A (enExample)
UY (1) UY31905A (enExample)
WO (1) WO2009154557A1 (enExample)
ZA (1) ZA201008886B (enExample)

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WO2009154557A1 (en) 2008-06-18 2009-12-23 Astrazeneca Ab Benzoxazinone derivatives acting as beta2-adrenoreceptor agonist for the treatment of respiratory disorders
WO2011048409A1 (en) 2009-10-20 2011-04-28 Astrazeneca Ab Cyclic amine derivatives having beta2 adrenergic receptor agonist and muscarinic receptor antagonist activity
WO2011073662A1 (en) 2009-12-17 2011-06-23 Astrazeneca Ab Combination of a benzoxazinone and a further agent for treating respiratory diseases
CN102993116A (zh) * 2012-12-04 2013-03-27 常州大学 一种苯并噁嗪类激动剂的制备方法
CA2953655C (en) * 2014-06-30 2020-05-12 Astrazeneca Ab Benzoxazinone amides as mineralocorticoid receptor modulators
CN104496920A (zh) * 2014-12-04 2015-04-08 北京理工大学 一种n-烯丙基-二取代四唑及其制备方法和检测方法
CN107188865B (zh) * 2016-03-14 2019-08-27 益方生物科技（上海）有限公司 苯并噁嗪化合物及其制备方法和用途
PL424609A1 (pl) * 2018-02-16 2019-08-26 Uniwersytet Przyrodniczy we Wrocławiu Zastosowanie 6-(tert-butylo)-3-dodecylo-3,4-dihydro-2H-benzo[e][1,3]oxazyny
CN110028521B (zh) * 2019-05-27 2020-07-14 湖南科技大学 11-芳基-1,4-苯并恶嗪酮并咪唑啉类化合物及其制备方法和用途
WO2023104564A1 (en) 2021-12-08 2023-06-15 Basf Se Pyrazine compounds for the control of invertebrate pests
EP4194453A1 (en) 2021-12-08 2023-06-14 Basf Se Pyrazine compounds for the control of invertebrate pests
CN117143019B (zh) * 2023-07-28 2025-11-25 常州大学 用作β2-肾上腺素受体别构拮抗剂的吡唑酰胺类衍生物

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GB0702456D0 (en) 2007-02-08 2007-03-21 Astrazeneca Ab New combination
GB0702457D0 (en) 2007-02-08 2007-03-21 Astrazeneca Ab New combination 666
GB0702458D0 (en) 2007-02-08 2007-03-21 Astrazeneca Ab Salts 668
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Also Published As

Publication number Publication date
BRPI0915428A2 (pt) 2015-11-03
CL2010001459A1 (es) 2011-09-23
ECSP10010694A (es) 2011-01-31
IL209731A0 (en) 2011-02-28
CO6321269A2 (es) 2011-09-20
EP2303873A1 (en) 2011-04-06
AU2009260899B2 (en) 2012-02-23
KR20110017456A (ko) 2011-02-21
WO2009154557A1 (en) 2009-12-23
EA201001747A1 (ru) 2011-08-30
AR072189A1 (es) 2010-08-11
US8017602B2 (en) 2011-09-13
CN102124003A (zh) 2011-07-13
EP2303873A4 (en) 2012-01-04
CA2726746A1 (en) 2009-12-23
UY31905A (es) 2010-01-29
AU2009260899A1 (en) 2009-12-23
TW201002696A (en) 2010-01-16
CR11856A (es) 2011-02-25
US20100105642A1 (en) 2010-04-29
JP2011524896A (ja) 2011-09-08
MX2010013477A (es) 2010-12-21
ZA201008886B (en) 2011-08-31

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