CA2726746A1 - Benzoxazinone derivatives acting as beta2-adrenoreceptor agonist for the treatment of respiratory disorders - Google Patents
Benzoxazinone derivatives acting as beta2-adrenoreceptor agonist for the treatment of respiratory disorders Download PDFInfo
- Publication number
- CA2726746A1 CA2726746A1 CA2726746A CA2726746A CA2726746A1 CA 2726746 A1 CA2726746 A1 CA 2726746A1 CA 2726746 A CA2726746 A CA 2726746A CA 2726746 A CA2726746 A CA 2726746A CA 2726746 A1 CA2726746 A1 CA 2726746A1
- Authority
- CA
- Canada
- Prior art keywords
- phenethoxy
- compound
- ethyl
- propanamide
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
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- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
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- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7342008P | 2008-06-18 | 2008-06-18 | |
| US61/073,420 | 2008-06-18 | ||
| PCT/SE2009/050749 WO2009154557A1 (en) | 2008-06-18 | 2009-06-17 | Benzoxazinone derivatives acting as beta2-adrenoreceptor agonist for the treatment of respiratory disorders |
Publications (1)
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|---|---|
| CA2726746A1 true CA2726746A1 (en) | 2009-12-23 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2726746A Abandoned CA2726746A1 (en) | 2008-06-18 | 2009-06-17 | Benzoxazinone derivatives acting as beta2-adrenoreceptor agonist for the treatment of respiratory disorders |
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| JP (1) | JP2011524896A (enExample) |
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| CL (1) | CL2010001459A1 (enExample) |
| CO (1) | CO6321269A2 (enExample) |
| CR (1) | CR11856A (enExample) |
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| EC (1) | ECSP10010694A (enExample) |
| IL (1) | IL209731A0 (enExample) |
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| UY (1) | UY31905A (enExample) |
| WO (1) | WO2009154557A1 (enExample) |
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| WO2011048409A1 (en) | 2009-10-20 | 2011-04-28 | Astrazeneca Ab | Cyclic amine derivatives having beta2 adrenergic receptor agonist and muscarinic receptor antagonist activity |
| WO2011073662A1 (en) | 2009-12-17 | 2011-06-23 | Astrazeneca Ab | Combination of a benzoxazinone and a further agent for treating respiratory diseases |
| CN102993116A (zh) * | 2012-12-04 | 2013-03-27 | 常州大学 | 一种苯并噁嗪类激动剂的制备方法 |
| ME03316B (me) * | 2014-06-30 | 2019-10-20 | Astrazeneca Ab | Benzoksazinon amidi као modulatori mineralokorтikoidnog receptora |
| CN104496920A (zh) * | 2014-12-04 | 2015-04-08 | 北京理工大学 | 一种n-烯丙基-二取代四唑及其制备方法和检测方法 |
| CN107188865B (zh) * | 2016-03-14 | 2019-08-27 | 益方生物科技（上海）有限公司 | 苯并噁嗪化合物及其制备方法和用途 |
| PL424609A1 (pl) * | 2018-02-16 | 2019-08-26 | Uniwersytet Przyrodniczy we Wrocławiu | Zastosowanie 6-(tert-butylo)-3-dodecylo-3,4-dihydro-2H-benzo[e][1,3]oxazyny |
| CN110028521B (zh) * | 2019-05-27 | 2020-07-14 | 湖南科技大学 | 11-芳基-1,4-苯并恶嗪酮并咪唑啉类化合物及其制备方法和用途 |
| EP4194453A1 (en) | 2021-12-08 | 2023-06-14 | Basf Se | Pyrazine compounds for the control of invertebrate pests |
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-
2009
- 2009-06-17 JP JP2011514537A patent/JP2011524896A/ja active Pending
- 2009-06-17 EP EP09766947A patent/EP2303873A4/en not_active Withdrawn
- 2009-06-17 AU AU2009260899A patent/AU2009260899B2/en not_active Ceased
- 2009-06-17 BR BRPI0915428A patent/BRPI0915428A2/pt not_active IP Right Cessation
- 2009-06-17 WO PCT/SE2009/050749 patent/WO2009154557A1/en not_active Ceased
- 2009-06-17 KR KR1020117001144A patent/KR20110017456A/ko not_active Withdrawn
- 2009-06-17 UY UY0001031905A patent/UY31905A/es unknown
- 2009-06-17 EA EA201001747A patent/EA201001747A1/ru unknown
- 2009-06-17 MX MX2010013477A patent/MX2010013477A/es active IP Right Grant
- 2009-06-17 TW TW098120291A patent/TW201002696A/zh unknown
- 2009-06-17 CA CA2726746A patent/CA2726746A1/en not_active Abandoned
- 2009-06-17 CN CN2009801320729A patent/CN102124003A/zh active Pending
- 2009-06-18 AR ARP090102225A patent/AR072189A1/es unknown
- 2009-06-18 US US12/486,854 patent/US8017602B2/en not_active Expired - Fee Related
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2010
- 2010-11-29 CO CO10150418A patent/CO6321269A2/es not_active Application Discontinuation
- 2010-12-02 IL IL209731A patent/IL209731A0/en unknown
- 2010-12-09 ZA ZA2010/08886A patent/ZA201008886B/en unknown
- 2010-12-17 DO DO2010000389A patent/DOP2010000389A/es unknown
- 2010-12-17 EC EC2010010694A patent/ECSP10010694A/es unknown
- 2010-12-17 CL CL2010001459A patent/CL2010001459A1/es unknown
- 2010-12-17 CR CR11856A patent/CR11856A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CR11856A (es) | 2011-02-25 |
| IL209731A0 (en) | 2011-02-28 |
| MX2010013477A (es) | 2010-12-21 |
| WO2009154557A1 (en) | 2009-12-23 |
| CL2010001459A1 (es) | 2011-09-23 |
| EP2303873A4 (en) | 2012-01-04 |
| AU2009260899B2 (en) | 2012-02-23 |
| US8017602B2 (en) | 2011-09-13 |
| KR20110017456A (ko) | 2011-02-21 |
| EP2303873A1 (en) | 2011-04-06 |
| AR072189A1 (es) | 2010-08-11 |
| DOP2010000389A (es) | 2011-01-15 |
| ECSP10010694A (es) | 2011-01-31 |
| AU2009260899A1 (en) | 2009-12-23 |
| ZA201008886B (en) | 2011-08-31 |
| JP2011524896A (ja) | 2011-09-08 |
| US20100105642A1 (en) | 2010-04-29 |
| BRPI0915428A2 (pt) | 2015-11-03 |
| CO6321269A2 (es) | 2011-09-20 |
| TW201002696A (en) | 2010-01-16 |
| CN102124003A (zh) | 2011-07-13 |
| EA201001747A1 (ru) | 2011-08-30 |
| UY31905A (es) | 2010-01-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20140617 |