DOP2007000082A - Inhibidores de quinasas de puntos de control - Google Patents

Inhibidores de quinasas de puntos de control

Info

Publication number
DOP2007000082A
DOP2007000082A DO2007000082A DO2007000082A DOP2007000082A DO P2007000082 A DOP2007000082 A DO P2007000082A DO 2007000082 A DO2007000082 A DO 2007000082A DO 2007000082 A DO2007000082 A DO 2007000082A DO P2007000082 A DOP2007000082 A DO P2007000082A
Authority
DO
Dominican Republic
Prior art keywords
kinase inhibitors
control points
points
kinase
inhibitors
Prior art date
Application number
DO2007000082A
Other languages
English (en)
Spanish (es)
Inventor
Kenneth L Arrington
Edward J Brnardic
Vadim Dudkin
Mark E Fraley
Shaei Y Huang
Cheng Wang
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DOP2007000082A publication Critical patent/DOP2007000082A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DO2007000082A 2006-04-25 2007-04-25 Inhibidores de quinasas de puntos de control DOP2007000082A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79469406P 2006-04-25 2006-04-25

Publications (1)

Publication Number Publication Date
DOP2007000082A true DOP2007000082A (es) 2007-12-31

Family

ID=38441857

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2007000082A DOP2007000082A (es) 2006-04-25 2007-04-25 Inhibidores de quinasas de puntos de control

Country Status (9)

Country Link
US (1) US7501435B2 (cg-RX-API-DMAC7.html)
EP (1) EP2013212A1 (cg-RX-API-DMAC7.html)
JP (1) JP5229221B2 (cg-RX-API-DMAC7.html)
AR (1) AR060619A1 (cg-RX-API-DMAC7.html)
AU (1) AU2007243520B2 (cg-RX-API-DMAC7.html)
CA (1) CA2649811A1 (cg-RX-API-DMAC7.html)
DO (1) DOP2007000082A (cg-RX-API-DMAC7.html)
TW (1) TW200806670A (cg-RX-API-DMAC7.html)
WO (1) WO2007127138A1 (cg-RX-API-DMAC7.html)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7485649B2 (en) * 2005-01-06 2009-02-03 Merck & Co., Inc. Inhibitors of checkpoint kinases
AU2006203963A1 (en) * 2005-01-06 2006-07-13 Merck Sharp & Dohme Corp. Inhibitors of checkpoint kinases
US7550477B2 (en) 2006-01-04 2009-06-23 Merck & Co., Inc. Inhibitors of checkpoint kinases
US9000027B2 (en) * 2008-02-04 2015-04-07 Dana-Farber Cancer Institute, Inc. Chk1 suppresses a caspase-2 apoptotic response to DNA damage that bypasses p53, bcl-2 and caspase-3
AU2009215073A1 (en) * 2008-02-14 2009-08-20 Merck Sharp & Dohme Corp. Inhibitors of checkpoint kinases
WO2010104933A1 (en) 2009-03-11 2010-09-16 Merck Sharp & Dohme Corp. Inhibitors of akt activity
US20140134178A1 (en) * 2012-01-06 2014-05-15 H. Lee Moffit Cancer Center And Research Institute Phosphorylation of histones and uses thereof
EP3024456A4 (en) 2013-07-26 2017-04-12 Update Pharma Inc. Combinatorial methods to improve the therapeutic benefit of bisantrene
TW201702218A (zh) 2014-12-12 2017-01-16 美國杰克森實驗室 關於治療癌症、自體免疫疾病及神經退化性疾病之組合物及方法
KR102875195B1 (ko) * 2019-04-03 2025-10-22 케미테라스, 인크. 티민 핵산 염기를 베이스로 하는 트리아졸로피리미딘류 및 그 제조 방법
PE20220376A1 (es) 2019-06-06 2022-03-16 Hutchison Medipharma Ltd Compuestos triciclicos y su uso
CN115197225B (zh) * 2021-09-03 2023-04-11 贵州大学 一种五元杂环并喹唑啉酮类化合物及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1244501A (en) * 1968-03-09 1971-09-02 Aspro Nicholas Ltd Heterocyclic amines
NZ287413A (en) * 1994-05-24 1998-02-26 Hoffmann La Roche Dioxo derivatives of triazoloquinazoline, isoxazoloquinoline, pyrazoloquinoline and analogs, medicaments
US5677309A (en) * 1996-03-22 1997-10-14 Neurogen Corporation 1,2,4-triazolo 4,3-c! quinazolin-3-ones and 1,2,4-triazolo 4,3-c!quinazolin-3-thiones; a new class of GABA brain receptor ligands
MXPA05009885A (es) * 2003-03-14 2005-12-05 Astrazeneca Ab Nuevas triazolonas fusionadas y los usos de las mismas.
KR100959771B1 (ko) * 2005-06-10 2010-05-28 머크 샤프 앤드 돔 코포레이션 Ａｋｔ 활성의 억제제
US7550477B2 (en) 2006-01-04 2009-06-23 Merck & Co., Inc. Inhibitors of checkpoint kinases

Also Published As

Publication number Publication date
EP2013212A1 (en) 2009-01-14
CA2649811A1 (en) 2007-11-08
US20070254879A1 (en) 2007-11-01
AU2007243520A1 (en) 2007-11-08
AU2007243520B2 (en) 2012-07-19
US7501435B2 (en) 2009-03-10
WO2007127138A1 (en) 2007-11-08
JP5229221B2 (ja) 2013-07-03
TW200806670A (en) 2008-02-01
JP2009535334A (ja) 2009-10-01
AR060619A1 (es) 2008-07-02

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