DK72886A - 5-(azolyloxyphenylcarbamoyl)barbitursyre-derivater samt deres fremstilling og anvendelse - Google Patents

5-(azolyloxyphenylcarbamoyl)barbitursyre-derivater samt deres fremstilling og anvendelse Download PDF

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Publication number
DK72886A
DK72886A DK72886A DK72886A DK72886A DK 72886 A DK72886 A DK 72886A DK 72886 A DK72886 A DK 72886A DK 72886 A DK72886 A DK 72886A DK 72886 A DK72886 A DK 72886A
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DK
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Prior art keywords
acid derivatives
c6alkyl
barbituric acid
azolyloxyphenyl
carbamoyl
Prior art date
Application number
DK72886A
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English (en)
Other versions
DK72886D0 (da
Inventor
Elmar Sturm
Jean Jacques Gallay
Haukur Kristinsson
Georg Pissiotas
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Ciba Geigy Ag
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Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK72886D0 publication Critical patent/DK72886D0/da
Publication of DK72886A publication Critical patent/DK72886A/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D271/00Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/101,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
    • C07D271/1131,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70One oxygen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60Three or more oxygen or sulfur atoms
    • C07D239/62Barbituric acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60Three or more oxygen or sulfur atoms
    • C07D239/66Thiobarbituric acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/101,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/58Nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/68Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01Five-membered rings
    • C07D285/02Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/081,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01Five-membered rings
    • C07D285/02Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/121,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
    • C07D285/1251,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • C07D285/13Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
DK72886A 1985-02-15 1986-02-14 5-(azolyloxyphenylcarbamoyl)barbitursyre-derivater samt deres fremstilling og anvendelse DK72886A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH70585 1985-02-15

Publications (2)

Publication Number Publication Date
DK72886D0 DK72886D0 (da) 1986-02-14
DK72886A true DK72886A (da) 1986-08-16

Family

ID=4193249

Family Applications (1)

Application Number Title Priority Date Filing Date
DK72886A DK72886A (da) 1985-02-15 1986-02-14 5-(azolyloxyphenylcarbamoyl)barbitursyre-derivater samt deres fremstilling og anvendelse

Country Status (17)

Country Link
US (1) US4762830A (da)
EP (1) EP0192180B1 (da)
JP (1) JPS61189282A (da)
AT (1) ATE45355T1 (da)
AU (1) AU599014B2 (da)
CA (1) CA1280114C (da)
DE (1) DE3664912D1 (da)
DK (1) DK72886A (da)
ES (2) ES8800175A1 (da)
GB (1) GB2171099B (da)
HU (1) HU195807B (da)
IE (1) IE860420L (da)
IL (1) IL77889A (da)
NZ (1) NZ215175A (da)
PH (2) PH24423A (da)
ZA (1) ZA861107B (da)
ZW (1) ZW3386A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2145087B (en) * 1983-08-19 1987-02-04 Ciba Geigy Ag Barbituric acid derivatives
US4879276A (en) * 1983-12-19 1989-11-07 Uniroyal Chemical Ltd./Uniroyal Chemical Ltee Method for reducing serum uric acid levels
GB2171099B (en) * 1985-02-15 1988-10-19 Ciba Geigy Ag 5-(azolyloxphenylcarbamoyl)barbituric acid derivatives as anthelmintics
US4888348A (en) * 1986-09-04 1989-12-19 Ciba-Geigy Corporation Substituted thioureas, isothioureas and carbodiimides
EP0430883A3 (en) * 1989-12-01 1991-11-06 Ciba-Geigy Ag Anthelmintical compounds
IE910278A1 (en) * 1990-02-16 1991-08-28 Ici Plc Heterocyclic compounds
US6235887B1 (en) * 1991-11-26 2001-05-22 Isis Pharmaceuticals, Inc. Enhanced triple-helix and double-helix formation directed by oligonucleotides containing modified pyrimidines
AUPO190596A0 (en) 1996-08-26 1996-09-19 Alchemia Pty Ltd Oligosaccharide synthesis
DE19710609A1 (de) 1997-03-14 1998-09-17 Bayer Ag Substituierte Aminosalicylsäureamide
AUPO937597A0 (en) * 1997-09-24 1997-10-16 Alchemia Pty Ltd Protecting and linking groups for organic synthesis
US9428466B2 (en) * 2013-11-13 2016-08-30 Raymond P. Warrell, Jr. Methods for reducing uric acid levels using barbiturate derivatives
EP3104861A4 (en) * 2014-02-14 2017-10-04 Warrell, Raymond P., Jr. Bifunctional compounds and use for reducing uric acid levels
CN107108526A (zh) 2015-01-22 2017-08-29 R·P·小沃勒尔 双功能化合物及用于降低尿酸水平的用途
TWI771303B (zh) 2016-06-30 2022-07-21 美商艾克奎斯特有限責任公司 化合物及其於降低尿酸位準之用途(一)
KR102444538B1 (ko) 2016-07-06 2022-09-16 애퀴스트 엘엘씨 요산 수치를 감소시키기 위한 화합물 및 이의 사용

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1539493A (en) * 1923-04-26 1925-05-26 Charles A Johnson Grain door
US3679695A (en) * 1970-12-14 1972-07-25 Minnesota Mining & Mfg Certain thiazolylhaloalkavesulforanilides
US3840550A (en) * 1971-05-24 1974-10-08 Ciba Geigy Corp Certain 6-isothiocyanobenzothiazoles
DE2405733C2 (de) * 1974-02-07 1984-12-13 Bayer Ag, 5090 Leverkusen Amidocarbonylthiobarbitursäurederivate und deren Salze, Verfahren zu ihrer Herstellung sowie ihre Verwendung zur Bekämpfung von Insekten, Milben und Pilzen
US4005202A (en) * 1974-02-11 1977-01-25 Syntex (U.S.A.) Inc. 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity
GB1499850A (en) * 1975-11-04 1978-02-01 Ici Ltd Process for the manufacture of 5-aminocarbonyl-2,4,6-trihydroxypyrimidine
DE2719777A1 (de) * 1976-05-06 1977-11-24 Ciba Geigy Ag Neue 5-phenylcarbamoyl-barbitursaeuren
DE2832698A1 (de) * 1978-07-26 1980-02-07 Bayer Ag Substituierte 5-phenylcarbamoyl- barbitursaeuren, verfahren zu ihrer herstellung und ihre verwendung als insektizide
US4283444A (en) * 1978-09-12 1981-08-11 Ciba-Geigy Corporation Method of protecting keratinous material from attack by insects that feed on keratin by treatment with 5-phenylcarbamoylbarbituric acid compounds
EP0105029A3 (de) * 1982-08-26 1985-05-22 Ciba-Geigy Ag Barbitursäurederivate als Anthelmintika
DE3238079A1 (de) * 1982-10-14 1984-04-19 Basf Ag, 6700 Ludwigshafen Anilinderivate, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung unerwuenschten pflanzenwuchses
GB2145087B (en) * 1983-08-19 1987-02-04 Ciba Geigy Ag Barbituric acid derivatives
IL73840A (en) * 1983-12-19 1988-11-15 Uniroyal Chem Co Inc 2-thio-5-(thio)carbamoyl barbituric acid derivatives,their preparation and pharmaceutical compositions containing them
CH657015A5 (de) * 1984-06-27 1986-08-15 Ciba Geigy Ag Motten- und kaeferschutzmittel.
EP0167491A3 (de) * 1984-07-06 1986-12-30 Ciba-Geigy Ag Thiobarbitursäurederivate
GB2171099B (en) * 1985-02-15 1988-10-19 Ciba Geigy Ag 5-(azolyloxphenylcarbamoyl)barbituric acid derivatives as anthelmintics

Also Published As

Publication number Publication date
IE860420L (en) 1986-08-15
ES8800175A1 (es) 1987-11-01
ZW3386A1 (en) 1986-11-05
GB2171099A (en) 1986-08-20
HUT40118A (en) 1986-11-28
PH24423A (en) 1990-06-25
GB8603352D0 (en) 1986-03-19
HU195807B (en) 1988-07-28
CA1280114C (en) 1991-02-12
ES556925A0 (es) 1988-02-16
ES8801638A1 (es) 1988-02-16
PH24447A (en) 1990-06-25
DK72886D0 (da) 1986-02-14
EP0192180A1 (de) 1986-08-27
DE3664912D1 (en) 1989-09-14
ES551973A0 (es) 1987-11-01
ATE45355T1 (de) 1989-08-15
AU5349286A (en) 1986-08-21
IL77889A (en) 1990-07-26
NZ215175A (en) 1989-08-29
JPS61189282A (ja) 1986-08-22
GB2171099B (en) 1988-10-19
AU599014B2 (en) 1990-07-12
US4762830A (en) 1988-08-09
EP0192180B1 (de) 1989-08-09
ZA861107B (en) 1986-09-24

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