FI860228A0 - Foerfarande foer framstaellning av farmakologiskt aktiva pyrrolo-benzimidazoler och mellanprodukter foer anvaendning daeri. - Google Patents
Foerfarande foer framstaellning av farmakologiskt aktiva pyrrolo-benzimidazoler och mellanprodukter foer anvaendning daeri.Info
- Publication number
- FI860228A0 FI860228A0 FI860228A FI860228A FI860228A0 FI 860228 A0 FI860228 A0 FI 860228A0 FI 860228 A FI860228 A FI 860228A FI 860228 A FI860228 A FI 860228A FI 860228 A0 FI860228 A0 FI 860228A0
- Authority
- FI
- Finland
- Prior art keywords
- alkyl
- foer
- pharmacologiskt
- benzimidazoler
- daeri
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Cephalosporin Compounds (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Indole Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI893090A FI893090A (fi) | 1985-01-18 | 1989-06-22 | Nya indolinderivat och foerfarande foer framstaellning av desamma. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19853501497 DE3501497A1 (de) | 1985-01-18 | 1985-01-18 | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte |
Publications (4)
Publication Number | Publication Date |
---|---|
FI860228A0 true FI860228A0 (fi) | 1986-01-17 |
FI860228A FI860228A (fi) | 1986-07-19 |
FI81579B FI81579B (fi) | 1990-07-31 |
FI81579C FI81579C (fi) | 1990-11-12 |
Family
ID=6260116
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI860228A FI81579C (fi) | 1985-01-18 | 1986-01-17 | Foerfarande foer framstaellning av farmakologiskt aktiva 6,7-dihydro-3h,5h-pyrrolo/2,3-f/bensimidazol-6-oner. |
Country Status (15)
Country | Link |
---|---|
US (1) | US4695567A (fi) |
EP (1) | EP0189103B1 (fi) |
JP (1) | JPS61167689A (fi) |
AT (1) | ATE59649T1 (fi) |
AU (1) | AU580832B2 (fi) |
DD (1) | DD253620A5 (fi) |
DE (2) | DE3501497A1 (fi) |
DK (1) | DK20786A (fi) |
ES (2) | ES8801832A1 (fi) |
FI (1) | FI81579C (fi) |
GR (1) | GR860144B (fi) |
HU (1) | HU194242B (fi) |
IL (1) | IL77582A (fi) |
SU (1) | SU1470191A3 (fi) |
ZA (1) | ZA86360B (fi) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3445669A1 (de) * | 1984-12-14 | 1986-06-19 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE3531678A1 (de) * | 1985-09-05 | 1987-03-12 | Boehringer Mannheim Gmbh | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE3626664A1 (de) * | 1986-08-07 | 1988-02-11 | Boehringer Mannheim Gmbh | Tricyclische benzotriazole, verfahren zu ihrer herstellung sowie arzneimittel |
DE3639466A1 (de) * | 1986-11-18 | 1988-05-19 | Thomae Gmbh Dr K | Neue pyrrolo-benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
DE3642315A1 (de) * | 1986-12-11 | 1988-06-23 | Boehringer Mannheim Gmbh | Neue pyrrolobenzimidazole, verfahren zu ihrer herstellung sowie arzneimittel |
DE3701277A1 (de) * | 1987-01-17 | 1988-07-28 | Boehringer Mannheim Gmbh | Neue tricyclische benzimidazole, verfahren zu ihrer herstellung und verwendung als arzneimittel |
DE3706427A1 (de) * | 1987-02-27 | 1988-09-08 | Boehringer Mannheim Gmbh | Neue substituierte 3h-indole, zwischenprodukte, verfahren zu ihrer herstellung sowie arzneimittel |
DE3740985A1 (de) * | 1987-12-03 | 1989-06-15 | Boehringer Mannheim Gmbh | Verwendung linear anellierter tricyclen als hemmer der erythrozytenaggregation |
DE3855327D1 (de) * | 1987-12-30 | 1996-07-04 | Orion Yhtymae Oy | Heterocyclische Verbindungen |
US4963677A (en) * | 1987-12-30 | 1990-10-16 | Orion Corporation Ltd. | Heterocyclic lactam compounds |
DE3803775A1 (de) * | 1988-02-09 | 1989-08-17 | Boehringer Mannheim Gmbh | Neue substituierte lactame, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten |
DE3809868A1 (de) * | 1988-03-24 | 1989-10-05 | Boehringer Mannheim Gmbh | Neue heterocyclisch substituierte 5,7-dihydro-pyrrolo(3,2-f)benzoxazol-6-one, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel |
DE4027592A1 (de) * | 1990-08-31 | 1992-03-05 | Beiersdorf Ag | Neue pyrrolobenzimidazole, imidazobenzoxazinone und imidazochinolone, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen |
AR050949A1 (es) * | 2004-09-24 | 2006-12-06 | Hoffmann La Roche | Derivados de 5,7-dihidro-1h-imidazol [4,5-f]indol o [4,5-g]quinolin-6-ona; su elaboracion y su uso en la preparacion de un medicamentop para el tratamiento del cancer |
US7285569B2 (en) | 2004-09-24 | 2007-10-23 | Hoff Hoffmann-La Roche Inc. | Tricycles, their manufacture and use as pharmaceutical agents |
US20060142247A1 (en) * | 2004-12-17 | 2006-06-29 | Guy Georges | Tricyclic heterocycles |
US7462639B2 (en) * | 2005-04-14 | 2008-12-09 | Hoffmann-La Roche Inc. | Aminopyrazole derivatives |
TW200719899A (en) * | 2005-04-14 | 2007-06-01 | Hoffmann La Roche | Tricyclic azole derivatives, their manufacture and use as pharmaceutical agents |
AU2006326247A1 (en) * | 2005-12-15 | 2007-06-21 | F. Hoffmann-La Roche Ag | Tricyclic lactam derivatives, their manufacture and use as pharmaceutical agents |
EP2001882A1 (en) * | 2006-03-23 | 2008-12-17 | F. Hoffmann-La Roche AG | Substituted indazole derivatives, their manufacture and use as pharmaceutical agents |
AU2013314417B2 (en) | 2012-09-13 | 2016-01-21 | F. Hoffmann-La Roche Ag | 2-oxo-2,3-dihydro-indoles for the treatment of CNS disorders |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IN148930B (fi) * | 1977-09-19 | 1981-07-25 | Hoffmann La Roche | |
DE3163018D1 (en) * | 1980-02-02 | 1984-05-17 | Beecham Group Plc | Pyrano derivatives, a process for their preparation and antihypertensive compositions containing them |
US4359465A (en) * | 1980-07-28 | 1982-11-16 | The Upjohn Company | Methods for treating gastrointestinal inflammation |
US4548946A (en) * | 1981-03-26 | 1985-10-22 | E. I. Du Pont De Nemours And Company | Antiinflammatory and/or analgesic 1,8-Dihydro-(or 3,8-dihydro)-8-aryl-2-[(substituted)thio]-indeno[1,2-d]imidazoles and their corresponding sulfoxides and sulfones |
DE3224512A1 (de) * | 1982-07-01 | 1984-01-05 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazolderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel |
GB8307865D0 (en) * | 1983-03-22 | 1983-04-27 | Fujisawa Pharmaceutical Co | Benzimidazole derivatives |
DE3410168A1 (de) * | 1984-03-20 | 1985-09-26 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue isochinolin-dione, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte |
GR851085B (fi) * | 1984-05-12 | 1985-11-25 | Boehringer Mannheim Gmbh | |
US4552876A (en) * | 1984-07-09 | 1985-11-12 | Usv Pharmaceutical Corp. | Bisbenzoxazines and pharmaceutical use |
DE3445669A1 (de) * | 1984-12-14 | 1986-06-19 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
-
1985
- 1985-01-18 DE DE19853501497 patent/DE3501497A1/de not_active Withdrawn
-
1986
- 1986-01-13 IL IL77582A patent/IL77582A/xx unknown
- 1986-01-14 AU AU52245/86A patent/AU580832B2/en not_active Ceased
- 1986-01-15 AT AT86100451T patent/ATE59649T1/de not_active IP Right Cessation
- 1986-01-15 EP EP86100451A patent/EP0189103B1/de not_active Expired - Lifetime
- 1986-01-15 DE DE8686100451T patent/DE3676313D1/de not_active Expired - Lifetime
- 1986-01-16 DK DK20786A patent/DK20786A/da not_active Application Discontinuation
- 1986-01-16 DD DD86286253A patent/DD253620A5/de unknown
- 1986-01-17 JP JP61006617A patent/JPS61167689A/ja active Pending
- 1986-01-17 HU HU86241A patent/HU194242B/hu not_active IP Right Cessation
- 1986-01-17 SU SU864012604A patent/SU1470191A3/ru active
- 1986-01-17 FI FI860228A patent/FI81579C/fi not_active Application Discontinuation
- 1986-01-17 ZA ZA86360A patent/ZA86360B/xx unknown
- 1986-01-17 US US06/820,259 patent/US4695567A/en not_active Expired - Fee Related
- 1986-01-17 ES ES551002A patent/ES8801832A1/es not_active Expired
- 1986-01-20 GR GR860144A patent/GR860144B/el unknown
-
1987
- 1987-12-09 ES ES557777A patent/ES8900123A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ES8801832A1 (es) | 1988-03-01 |
SU1470191A3 (ru) | 1989-03-30 |
GR860144B (en) | 1986-05-16 |
FI860228A (fi) | 1986-07-19 |
HUT41791A (en) | 1987-05-28 |
EP0189103A3 (en) | 1987-12-23 |
HU194242B (en) | 1988-01-28 |
ES8900123A1 (es) | 1989-01-16 |
DK20786D0 (da) | 1986-01-16 |
EP0189103A2 (de) | 1986-07-30 |
DK20786A (da) | 1986-07-19 |
DD253620A5 (de) | 1988-01-27 |
AU580832B2 (en) | 1989-02-02 |
ES551002A0 (es) | 1988-03-01 |
FI81579B (fi) | 1990-07-31 |
FI81579C (fi) | 1990-11-12 |
DE3676313D1 (de) | 1991-02-07 |
IL77582A (en) | 1990-01-18 |
AU5224586A (en) | 1986-07-24 |
JPS61167689A (ja) | 1986-07-29 |
ATE59649T1 (de) | 1991-01-15 |
DE3501497A1 (de) | 1986-07-24 |
ZA86360B (en) | 1986-09-24 |
ES557777A0 (es) | 1989-01-16 |
US4695567A (en) | 1987-09-22 |
EP0189103B1 (de) | 1991-01-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Application withdrawn |
Owner name: BOEHRINGER MANNHEIM GMBH |