DK20786A - Pyrrolo-benzimidazoler og fremgangsmaade til fremstilling deraf samt laegemidler indeholdende disse forbindelser - Google Patents
Pyrrolo-benzimidazoler og fremgangsmaade til fremstilling deraf samt laegemidler indeholdende disse forbindelser Download PDFInfo
- Publication number
- DK20786A DK20786A DK20786A DK20786A DK20786A DK 20786 A DK20786 A DK 20786A DK 20786 A DK20786 A DK 20786A DK 20786 A DK20786 A DK 20786A DK 20786 A DK20786 A DK 20786A
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- alkenyl
- compounds
- hydroxyl
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Cephalosporin Compounds (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19853501497 DE3501497A1 (de) | 1985-01-18 | 1985-01-18 | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK20786D0 DK20786D0 (da) | 1986-01-16 |
| DK20786A true DK20786A (da) | 1986-07-19 |
Family
ID=6260116
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK20786A DK20786A (da) | 1985-01-18 | 1986-01-16 | Pyrrolo-benzimidazoler og fremgangsmaade til fremstilling deraf samt laegemidler indeholdende disse forbindelser |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4695567A (da) |
| EP (1) | EP0189103B1 (da) |
| JP (1) | JPS61167689A (da) |
| AT (1) | ATE59649T1 (da) |
| AU (1) | AU580832B2 (da) |
| DD (1) | DD253620A5 (da) |
| DE (2) | DE3501497A1 (da) |
| DK (1) | DK20786A (da) |
| ES (2) | ES8801832A1 (da) |
| FI (1) | FI81579C (da) |
| GR (1) | GR860144B (da) |
| HU (1) | HU194242B (da) |
| IL (1) | IL77582A (da) |
| SU (1) | SU1470191A3 (da) |
| ZA (1) | ZA86360B (da) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3445669A1 (de) * | 1984-12-14 | 1986-06-19 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE3531678A1 (de) * | 1985-09-05 | 1987-03-12 | Boehringer Mannheim Gmbh | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE3626664A1 (de) * | 1986-08-07 | 1988-02-11 | Boehringer Mannheim Gmbh | Tricyclische benzotriazole, verfahren zu ihrer herstellung sowie arzneimittel |
| DE3639466A1 (de) * | 1986-11-18 | 1988-05-19 | Thomae Gmbh Dr K | Neue pyrrolo-benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| DE3642315A1 (de) * | 1986-12-11 | 1988-06-23 | Boehringer Mannheim Gmbh | Neue pyrrolobenzimidazole, verfahren zu ihrer herstellung sowie arzneimittel |
| DE3701277A1 (de) * | 1987-01-17 | 1988-07-28 | Boehringer Mannheim Gmbh | Neue tricyclische benzimidazole, verfahren zu ihrer herstellung und verwendung als arzneimittel |
| DE3706427A1 (de) * | 1987-02-27 | 1988-09-08 | Boehringer Mannheim Gmbh | Neue substituierte 3h-indole, zwischenprodukte, verfahren zu ihrer herstellung sowie arzneimittel |
| DE3740985A1 (de) * | 1987-12-03 | 1989-06-15 | Boehringer Mannheim Gmbh | Verwendung linear anellierter tricyclen als hemmer der erythrozytenaggregation |
| ATE138658T1 (de) * | 1987-12-30 | 1996-06-15 | Orion Yhtymae Oy | Heterocyclische verbindungen |
| US4963677A (en) * | 1987-12-30 | 1990-10-16 | Orion Corporation Ltd. | Heterocyclic lactam compounds |
| DE3803775A1 (de) * | 1988-02-09 | 1989-08-17 | Boehringer Mannheim Gmbh | Neue substituierte lactame, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten |
| DE3809868A1 (de) * | 1988-03-24 | 1989-10-05 | Boehringer Mannheim Gmbh | Neue heterocyclisch substituierte 5,7-dihydro-pyrrolo(3,2-f)benzoxazol-6-one, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel |
| DE4027592A1 (de) * | 1990-08-31 | 1992-03-05 | Beiersdorf Ag | Neue pyrrolobenzimidazole, imidazobenzoxazinone und imidazochinolone, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen |
| TW200626149A (en) * | 2004-09-24 | 2006-08-01 | Hoffmann La Roche | Tricycles, their manufacture and use as pharmaceutical agents |
| US7285569B2 (en) | 2004-09-24 | 2007-10-23 | Hoff Hoffmann-La Roche Inc. | Tricycles, their manufacture and use as pharmaceutical agents |
| US20060142247A1 (en) * | 2004-12-17 | 2006-06-29 | Guy Georges | Tricyclic heterocycles |
| TW200719899A (en) * | 2005-04-14 | 2007-06-01 | Hoffmann La Roche | Tricyclic azole derivatives, their manufacture and use as pharmaceutical agents |
| JP2008535876A (ja) * | 2005-04-14 | 2008-09-04 | エフ．ホフマン−ラ ロシュ アーゲー | アミノピラゾール誘導体、これらの製造、及び医薬製剤としての使用。 |
| AU2006326247A1 (en) * | 2005-12-15 | 2007-06-21 | F. Hoffmann-La Roche Ag | Tricyclic lactam derivatives, their manufacture and use as pharmaceutical agents |
| CN101400681A (zh) * | 2006-03-23 | 2009-04-01 | 霍夫曼-拉罗奇有限公司 | 取代的吲唑衍生物，它们的制备和作为药剂的应用 |
| KR101706877B1 (ko) | 2012-09-13 | 2017-02-15 | 에프. 호프만-라 로슈 아게 | Cns 장애의 치료를 위한 2-옥소-2,3-다이하이드로-인돌 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN148930B (da) * | 1977-09-19 | 1981-07-25 | Hoffmann La Roche | |
| DE3163018D1 (en) * | 1980-02-02 | 1984-05-17 | Beecham Group Plc | Pyrano derivatives, a process for their preparation and antihypertensive compositions containing them |
| US4359465A (en) * | 1980-07-28 | 1982-11-16 | The Upjohn Company | Methods for treating gastrointestinal inflammation |
| US4548946A (en) * | 1981-03-26 | 1985-10-22 | E. I. Du Pont De Nemours And Company | Antiinflammatory and/or analgesic 1,8-Dihydro-(or 3,8-dihydro)-8-aryl-2-[(substituted)thio]-indeno[1,2-d]imidazoles and their corresponding sulfoxides and sulfones |
| DE3224512A1 (de) * | 1982-07-01 | 1984-01-05 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazolderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel |
| GB8307865D0 (en) * | 1983-03-22 | 1983-04-27 | Fujisawa Pharmaceutical Co | Benzimidazole derivatives |
| DE3410168A1 (de) * | 1984-03-20 | 1985-09-26 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue isochinolin-dione, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte |
| PL144822B1 (en) * | 1984-05-12 | 1988-07-30 | Boehringer Mannheim Gmbh | Method of obtaining novel pyrolobenzimidazoles |
| US4552876A (en) * | 1984-07-09 | 1985-11-12 | Usv Pharmaceutical Corp. | Bisbenzoxazines and pharmaceutical use |
| DE3445669A1 (de) * | 1984-12-14 | 1986-06-19 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
-
1985
- 1985-01-18 DE DE19853501497 patent/DE3501497A1/de not_active Withdrawn
-
1986
- 1986-01-13 IL IL77582A patent/IL77582A/xx unknown
- 1986-01-14 AU AU52245/86A patent/AU580832B2/en not_active Ceased
- 1986-01-15 AT AT86100451T patent/ATE59649T1/de not_active IP Right Cessation
- 1986-01-15 EP EP86100451A patent/EP0189103B1/de not_active Expired - Lifetime
- 1986-01-15 DE DE8686100451T patent/DE3676313D1/de not_active Expired - Lifetime
- 1986-01-16 DD DD86286253A patent/DD253620A5/de unknown
- 1986-01-16 DK DK20786A patent/DK20786A/da not_active Application Discontinuation
- 1986-01-17 JP JP61006617A patent/JPS61167689A/ja active Pending
- 1986-01-17 ZA ZA86360A patent/ZA86360B/xx unknown
- 1986-01-17 SU SU864012604A patent/SU1470191A3/ru active
- 1986-01-17 ES ES551002A patent/ES8801832A1/es not_active Expired
- 1986-01-17 FI FI860228A patent/FI81579C/fi not_active Application Discontinuation
- 1986-01-17 HU HU86241A patent/HU194242B/hu not_active IP Right Cessation
- 1986-01-17 US US06/820,259 patent/US4695567A/en not_active Expired - Fee Related
- 1986-01-20 GR GR860144A patent/GR860144B/el unknown
-
1987
- 1987-12-09 ES ES557777A patent/ES8900123A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE3501497A1 (de) | 1986-07-24 |
| DD253620A5 (de) | 1988-01-27 |
| AU5224586A (en) | 1986-07-24 |
| ATE59649T1 (de) | 1991-01-15 |
| FI81579B (fi) | 1990-07-31 |
| HU194242B (en) | 1988-01-28 |
| ES8801832A1 (es) | 1988-03-01 |
| DE3676313D1 (de) | 1991-02-07 |
| AU580832B2 (en) | 1989-02-02 |
| GR860144B (en) | 1986-05-16 |
| EP0189103A2 (de) | 1986-07-30 |
| JPS61167689A (ja) | 1986-07-29 |
| ES557777A0 (es) | 1989-01-16 |
| IL77582A (en) | 1990-01-18 |
| ES8900123A1 (es) | 1989-01-16 |
| EP0189103A3 (en) | 1987-12-23 |
| SU1470191A3 (ru) | 1989-03-30 |
| US4695567A (en) | 1987-09-22 |
| ES551002A0 (es) | 1988-03-01 |
| FI860228A0 (fi) | 1986-01-17 |
| ZA86360B (en) | 1986-09-24 |
| FI860228A (fi) | 1986-07-19 |
| EP0189103B1 (de) | 1991-01-02 |
| DK20786D0 (da) | 1986-01-16 |
| HUT41791A (en) | 1987-05-28 |
| FI81579C (fi) | 1990-11-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |