DK20786D0 - Pyrrolo-benzimidazoler og fremgangsmaade til fremstilling deraf samt laegemidler indeholdende disse forbindelser - Google Patents

Pyrrolo-benzimidazoler og fremgangsmaade til fremstilling deraf samt laegemidler indeholdende disse forbindelser

Info

Publication number
DK20786D0
DK20786D0 DK20786A DK20786A DK20786D0 DK 20786 D0 DK20786 D0 DK 20786D0 DK 20786 A DK20786 A DK 20786A DK 20786 A DK20786 A DK 20786A DK 20786 D0 DK20786 D0 DK 20786D0
Authority
DK
Denmark
Prior art keywords
alkyl
alkenyl
compounds
hydroxyl
amino
Prior art date
Application number
DK20786A
Other languages
English (en)
Other versions
DK20786A (da
Inventor
Alfred Mertens
Jens-Peter Hoelck
Herbert Berger
Bernd Mueller-Beckmann
Klaus Strein
Egon Roesch
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of DK20786D0 publication Critical patent/DK20786D0/da
Publication of DK20786A publication Critical patent/DK20786A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Cephalosporin Compounds (AREA)
DK20786A 1985-01-18 1986-01-16 Pyrrolo-benzimidazoler og fremgangsmaade til fremstilling deraf samt laegemidler indeholdende disse forbindelser DK20786A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853501497 DE3501497A1 (de) 1985-01-18 1985-01-18 Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte

Publications (2)

Publication Number Publication Date
DK20786D0 true DK20786D0 (da) 1986-01-16
DK20786A DK20786A (da) 1986-07-19

Family

ID=6260116

Family Applications (1)

Application Number Title Priority Date Filing Date
DK20786A DK20786A (da) 1985-01-18 1986-01-16 Pyrrolo-benzimidazoler og fremgangsmaade til fremstilling deraf samt laegemidler indeholdende disse forbindelser

Country Status (15)

Country Link
US (1) US4695567A (da)
EP (1) EP0189103B1 (da)
JP (1) JPS61167689A (da)
AT (1) ATE59649T1 (da)
AU (1) AU580832B2 (da)
DD (1) DD253620A5 (da)
DE (2) DE3501497A1 (da)
DK (1) DK20786A (da)
ES (2) ES8801832A1 (da)
FI (1) FI81579C (da)
GR (1) GR860144B (da)
HU (1) HU194242B (da)
IL (1) IL77582A (da)
SU (1) SU1470191A3 (da)
ZA (1) ZA86360B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3445669A1 (de) * 1984-12-14 1986-06-19 Boehringer Mannheim Gmbh, 6800 Mannheim Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3531678A1 (de) * 1985-09-05 1987-03-12 Boehringer Mannheim Gmbh Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3626664A1 (de) * 1986-08-07 1988-02-11 Boehringer Mannheim Gmbh Tricyclische benzotriazole, verfahren zu ihrer herstellung sowie arzneimittel
DE3639466A1 (de) * 1986-11-18 1988-05-19 Thomae Gmbh Dr K Neue pyrrolo-benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DE3642315A1 (de) * 1986-12-11 1988-06-23 Boehringer Mannheim Gmbh Neue pyrrolobenzimidazole, verfahren zu ihrer herstellung sowie arzneimittel
DE3701277A1 (de) * 1987-01-17 1988-07-28 Boehringer Mannheim Gmbh Neue tricyclische benzimidazole, verfahren zu ihrer herstellung und verwendung als arzneimittel
DE3706427A1 (de) * 1987-02-27 1988-09-08 Boehringer Mannheim Gmbh Neue substituierte 3h-indole, zwischenprodukte, verfahren zu ihrer herstellung sowie arzneimittel
DE3740985A1 (de) * 1987-12-03 1989-06-15 Boehringer Mannheim Gmbh Verwendung linear anellierter tricyclen als hemmer der erythrozytenaggregation
US4963677A (en) * 1987-12-30 1990-10-16 Orion Corporation Ltd. Heterocyclic lactam compounds
EP0322746B1 (en) * 1987-12-30 1996-05-29 Orion Corporation Limited Heterocyclic compounds
DE3803775A1 (de) * 1988-02-09 1989-08-17 Boehringer Mannheim Gmbh Neue substituierte lactame, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten
DE3809868A1 (de) * 1988-03-24 1989-10-05 Boehringer Mannheim Gmbh Neue heterocyclisch substituierte 5,7-dihydro-pyrrolo(3,2-f)benzoxazol-6-one, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
DE4027592A1 (de) * 1990-08-31 1992-03-05 Beiersdorf Ag Neue pyrrolobenzimidazole, imidazobenzoxazinone und imidazochinolone, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
US7285569B2 (en) 2004-09-24 2007-10-23 Hoff Hoffmann-La Roche Inc. Tricycles, their manufacture and use as pharmaceutical agents
TW200626149A (en) * 2004-09-24 2006-08-01 Hoffmann La Roche Tricycles, their manufacture and use as pharmaceutical agents
US20060142247A1 (en) * 2004-12-17 2006-06-29 Guy Georges Tricyclic heterocycles
WO2006108489A1 (en) * 2005-04-14 2006-10-19 F. Hoffmann-La Roche Ag Aminopyrazole derivatives, their manufacture and use as pharmaceutical agents
DE602006002887D1 (de) * 2005-04-14 2008-11-06 Hoffmann La Roche Tricyclische azolderivate, ihre herstellung und ihre verwendung als pharmazeutische mittel
US20090143375A1 (en) * 2005-12-15 2009-06-04 F. Hoffmann-La Roche Ag Tricyclic Lactam Derivatives, Their Manufacture and Use as Pharmaceutical Agents
US20090291968A1 (en) * 2006-03-23 2009-11-26 Guy Georges Substituted indazole derivatives, their manufacture and use as pharmaceutical agents
EA027176B1 (ru) 2012-09-13 2017-06-30 Ф. Хоффманн-Ля Рош Аг 2-оксо-2,3-дигидроиндолы для лечения расстройств центральной нервной системы

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN148930B (da) * 1977-09-19 1981-07-25 Hoffmann La Roche
EP0033612B1 (en) * 1980-02-02 1984-04-11 Beecham Group Plc Pyrano derivatives, a process for their preparation and antihypertensive compositions containing them
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
US4548946A (en) * 1981-03-26 1985-10-22 E. I. Du Pont De Nemours And Company Antiinflammatory and/or analgesic 1,8-Dihydro-(or 3,8-dihydro)-8-aryl-2-[(substituted)thio]-indeno[1,2-d]imidazoles and their corresponding sulfoxides and sulfones
DE3224512A1 (de) * 1982-07-01 1984-01-05 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazolderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel
GB8307865D0 (en) * 1983-03-22 1983-04-27 Fujisawa Pharmaceutical Co Benzimidazole derivatives
DE3410168A1 (de) * 1984-03-20 1985-09-26 Boehringer Mannheim Gmbh, 6800 Mannheim Neue isochinolin-dione, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte
PL144822B1 (en) * 1984-05-12 1988-07-30 Boehringer Mannheim Gmbh Method of obtaining novel pyrolobenzimidazoles
US4552876A (en) * 1984-07-09 1985-11-12 Usv Pharmaceutical Corp. Bisbenzoxazines and pharmaceutical use
DE3445669A1 (de) * 1984-12-14 1986-06-19 Boehringer Mannheim Gmbh, 6800 Mannheim Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
FI81579C (fi) 1990-11-12
ES8801832A1 (es) 1988-03-01
DK20786A (da) 1986-07-19
US4695567A (en) 1987-09-22
HU194242B (en) 1988-01-28
ZA86360B (en) 1986-09-24
HUT41791A (en) 1987-05-28
FI860228A0 (fi) 1986-01-17
IL77582A (en) 1990-01-18
JPS61167689A (ja) 1986-07-29
DE3501497A1 (de) 1986-07-24
EP0189103A2 (de) 1986-07-30
ATE59649T1 (de) 1991-01-15
EP0189103A3 (en) 1987-12-23
FI860228A (fi) 1986-07-19
SU1470191A3 (ru) 1989-03-30
DD253620A5 (de) 1988-01-27
ES8900123A1 (es) 1989-01-16
AU5224586A (en) 1986-07-24
ES551002A0 (es) 1988-03-01
FI81579B (fi) 1990-07-31
GR860144B (en) 1986-05-16
EP0189103B1 (de) 1991-01-02
AU580832B2 (en) 1989-02-02
DE3676313D1 (de) 1991-02-07
ES557777A0 (es) 1989-01-16

Similar Documents

Publication Publication Date Title
DK20786A (da) Pyrrolo-benzimidazoler og fremgangsmaade til fremstilling deraf samt laegemidler indeholdende disse forbindelser
DE3888854D1 (de) Neue tricyclische Benzimidazole, Verfahren zu ihrer Herstellung und Verwendung als Arzneimittel.
ATE46164T1 (de) 1,4:3,6-dianhydro-hexit-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
ES8801638A1 (es) Procedimiento para la obtencion de derivados de acido 5-(azoliloxifenilcarbamoil)-barbiturico
ATE13885T1 (de) Phenylpiperazinderivate von hetarylphenolen und hetarylanilinen, ihre herstellung und diese enthaltende therapeutische mittel.
DK165247C (da) 2,3,4,5-substituerede 1,6-naphthyridinderivater, deres fremstilling samt anvendelse af disse til fremstilling af laegemidler til bekaempelse af cardiale, cerebrale og perifere karlidelser, myocardial iskaemi, cerebral infarkt, lungethrombose, stenoser, arterioscleroser og hjerte-kredsloebslidelser og laegemiddel indeholdende disse derivater
ATE106400T1 (de) Substituierte 3h-indole, verfahren zu ihrer herstellung sowie arzneimittel.
DK141187D0 (da) 1-(3-(2-dialkylaminoethoxy)-2-thienyl)-3-phenyl-1-propanoner og syreadditionssalte deraf, fremgangsmaade af saadanne forbindelser samt farmaceutiske praeparater indeholdende disse
GR3004372T3 (da)
NO933478L (no) 6-heterocyklisk-4-amino-1,2,2a,3,4,5-heksahydrobenz(CD)indoler for behandling av reisesyke og oppkast
ATE59650T1 (de) Tricyclische benzotriazole, verfahren zu ihrer herstellung sowie arzneimittel.

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment