DK692674A - - Google Patents

Info

Publication number
DK692674A
DK692674A DK692674A DK692674A DK692674A DK 692674 A DK692674 A DK 692674A DK 692674 A DK692674 A DK 692674A DK 692674 A DK692674 A DK 692674A DK 692674 A DK692674 A DK 692674A
Authority
DK
Denmark
Application number
DK692674A
Other languages
Danish (da)
Other versions
DK152368B (da
DK152368C (da
Inventor
M A Kaplan
A P Granatek
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of DK692674A publication Critical patent/DK692674A/da
Publication of DK152368B publication Critical patent/DK152368B/da
Application granted granted Critical
Publication of DK152368C publication Critical patent/DK152368C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
DK692674A 1974-01-07 1974-12-30 Fremgangsmaade til fremstilling af krystallinsk 7-oed-alfa-amino-alfa-(p-hydroxyphenyl)acetamidoaa-3-(1,2,3-triazol-5-ylthiomethyl)-3-cephem-4-carboxylsyre-1,2-propylenglycolat DK152368C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US43125174A 1974-01-07 1974-01-07
US43125174 1974-01-07
US05/534,114 US3970651A (en) 1974-01-07 1974-12-18 Crystalline cephalosporin derivative
US53411474 1974-12-18

Publications (3)

Publication Number Publication Date
DK692674A true DK692674A (nl) 1975-09-01
DK152368B DK152368B (da) 1988-02-22
DK152368C DK152368C (da) 1988-07-25

Family

ID=27028950

Family Applications (1)

Application Number Title Priority Date Filing Date
DK692674A DK152368C (da) 1974-01-07 1974-12-30 Fremgangsmaade til fremstilling af krystallinsk 7-oed-alfa-amino-alfa-(p-hydroxyphenyl)acetamidoaa-3-(1,2,3-triazol-5-ylthiomethyl)-3-cephem-4-carboxylsyre-1,2-propylenglycolat

Country Status (17)

Country Link
US (1) US3970651A (nl)
JP (1) JPS6020394B2 (nl)
CA (1) CA1060886A (nl)
CH (1) CH612978A5 (nl)
DE (1) DE2500386C2 (nl)
DK (1) DK152368C (nl)
FI (1) FI66388C (nl)
GB (1) GB1483416A (nl)
HK (1) HK40981A (nl)
HU (1) HU168901B (nl)
IE (1) IE41883B1 (nl)
IL (1) IL46390A (nl)
KE (1) KE3150A (nl)
MY (1) MY8200099A (nl)
NL (1) NL185924C (nl)
OA (1) OA04876A (nl)
SE (1) SE422064B (nl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2400519A1 (fr) * 1977-08-17 1979-03-16 Roussel Uclaf Forme cristalline du sel de sodium d'un derive oximine de l'acide 7-amino-thiazolyl acetamido cephalosporanique, son procede de preparation et son application comme medicament
EP0052094A1 (en) * 1979-04-25 1982-05-19 BIOCHEMIE Gesellschaft m.b.H. N-isopropoxycarbonylphenylglycines and their production
IT1233864B (it) * 1988-02-24 1992-04-21 Opos Biochimica Srl Procedimento per la fabbricazione dell'acido 7-(d-(-)-alfa-amino-alfa -(p-idrossifenil)acetamido)-3-(1,2,3-triazol-4(5)-il)tiometil-3-cefem -4-carbossilico 1,2,-propilenglicolato e intermedio alogenato di detto procedimento
US20100311701A1 (en) * 2002-02-15 2010-12-09 Transform Pharmaceuticals, Inc Pharmaceutical Co-Crystal Compositions
US7790905B2 (en) * 2002-02-15 2010-09-07 Mcneil-Ppc, Inc. Pharmaceutical propylene glycol solvate compositions
US7927613B2 (en) * 2002-02-15 2011-04-19 University Of South Florida Pharmaceutical co-crystal compositions
CA2477923C (en) * 2002-03-01 2021-02-23 University Of South Florida Multiple-component solid phases containing at least one active pharmaceutical ingredient
CA2489984A1 (en) * 2002-06-21 2003-12-31 Transform Pharmaceuticals, Inc. Pharmaceutical compositions with improved dissolution
US8183290B2 (en) 2002-12-30 2012-05-22 Mcneil-Ppc, Inc. Pharmaceutically acceptable propylene glycol solvate of naproxen
US7230097B2 (en) * 2003-03-10 2007-06-12 Lupin Ltd. Process for preparation of 7-[α-Amino (4-hydroxyphenyl) acetamido]-3-substituted-3-cephem-4-carboxylic acid
CA2570949A1 (en) * 2006-12-12 2008-06-12 Apotex Pharmachem Inc. Ibandronate sodium propylene glycol solvate and processes for the preparation thereof
US7834195B2 (en) * 2007-01-24 2010-11-16 Apotex Pharmachem Inc. Atorvastatin calcium propylene glycol solvates
PE20090185A1 (es) 2007-03-22 2009-02-28 Bristol Myers Squibb Co Formulaciones farmaceuticas que contienen un inhibidor sglt2

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1316964A (en) * 1969-07-24 1973-05-16 Glaxo Lab Ltd Antibiotics
US3867380A (en) * 1971-02-18 1975-02-18 Smithkline Corp 3-Heterocyclic thiomethylcephalosporins
US3855213A (en) * 1971-02-18 1974-12-17 Smith Kline French Lab 3-heterocyclic thiomethyl-cephalosporins

Also Published As

Publication number Publication date
JPS50105813A (nl) 1975-08-20
OA04876A (fr) 1980-10-31
NL185924C (nl) 1990-08-16
DE2500386C2 (de) 1983-10-13
SE7500123L (nl) 1975-07-08
MY8200099A (en) 1982-12-31
CA1060886A (en) 1979-08-21
FI66388C (fi) 1984-10-10
JPS6020394B2 (ja) 1985-05-21
US3970651A (en) 1976-07-20
FI66388B (fi) 1984-06-29
IL46390A (en) 1978-01-31
DK152368B (da) 1988-02-22
CH612978A5 (nl) 1979-08-31
FI750002A (nl) 1975-07-08
IE41883L (en) 1975-07-07
DE2500386A1 (de) 1975-07-17
GB1483416A (en) 1977-08-17
IL46390A0 (en) 1976-06-30
HU168901B (nl) 1976-08-28
IE41883B1 (en) 1980-04-23
NL185924B (nl) 1990-03-16
DK152368C (da) 1988-07-25
KE3150A (en) 1981-08-28
SE422064B (sv) 1982-02-15
HK40981A (en) 1981-08-28
NL7500167A (nl) 1975-07-09

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Legal Events

Date Code Title Description
PUP Patent expired