DK650187A - Hidtil ukendte pyrrolobenzimidazoler, fremgangsmaade til fremstilling deraf samt laegemiddel, der indeholder disse forbindelser - Google Patents

Hidtil ukendte pyrrolobenzimidazoler, fremgangsmaade til fremstilling deraf samt laegemiddel, der indeholder disse forbindelser

Info

Publication number
DK650187A
DK650187A DK650187A DK650187A DK650187A DK 650187 A DK650187 A DK 650187A DK 650187 A DK650187 A DK 650187A DK 650187 A DK650187 A DK 650187A DK 650187 A DK650187 A DK 650187A
Authority
DK
Denmark
Prior art keywords
pyrrolobenzimidazoles
unknown
procedures
compounds
production
Prior art date
Application number
DK650187A
Other languages
English (en)
Other versions
DK650187D0 (da
Inventor
Walter-Gunar Friebe
Alfred Mertens
Klaus Strein
Erwin Boehm
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of DK650187D0 publication Critical patent/DK650187D0/da
Publication of DK650187A publication Critical patent/DK650187A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK650187A 1986-12-11 1987-12-10 Hidtil ukendte pyrrolobenzimidazoler, fremgangsmaade til fremstilling deraf samt laegemiddel, der indeholder disse forbindelser DK650187A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863642315 DE3642315A1 (de) 1986-12-11 1986-12-11 Neue pyrrolobenzimidazole, verfahren zu ihrer herstellung sowie arzneimittel

Publications (2)

Publication Number Publication Date
DK650187D0 DK650187D0 (da) 1987-12-10
DK650187A true DK650187A (da) 1988-06-12

Family

ID=6315954

Family Applications (1)

Application Number Title Priority Date Filing Date
DK650187A DK650187A (da) 1986-12-11 1987-12-10 Hidtil ukendte pyrrolobenzimidazoler, fremgangsmaade til fremstilling deraf samt laegemiddel, der indeholder disse forbindelser

Country Status (13)

Country Link
US (1) US4863945A (da)
EP (1) EP0271040A3 (da)
JP (1) JPS63162692A (da)
KR (1) KR880007536A (da)
AU (1) AU8245087A (da)
DD (1) DD267047A5 (da)
DE (1) DE3642315A1 (da)
DK (1) DK650187A (da)
FI (1) FI875438A (da)
HU (1) HU200339B (da)
IL (1) IL84589A0 (da)
PT (1) PT86331B (da)
ZA (1) ZA879166B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5206240A (en) * 1989-12-08 1993-04-27 Merck & Co., Inc. Nitrogen-containing spirocycles
DE4027592A1 (de) * 1990-08-31 1992-03-05 Beiersdorf Ag Neue pyrrolobenzimidazole, imidazobenzoxazinone und imidazochinolone, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
US5434163A (en) * 1993-05-14 1995-07-18 The Medical College Of Pennsylvania Treatment of Cryptococcus neoformans infection
US6184226B1 (en) 1998-08-28 2001-02-06 Scios Inc. Quinazoline derivatives as inhibitors of P-38 α
US6995162B2 (en) 2001-01-12 2006-02-07 Amgen Inc. Substituted alkylamine derivatives and methods of use
US6878714B2 (en) * 2001-01-12 2005-04-12 Amgen Inc. Substituted alkylamine derivatives and methods of use
EP1598353A1 (en) * 2004-05-17 2005-11-23 Boehringer Ingelheim International GmbH Pyrrolobenzimidazolones and their use as antiproliferative agents
US7285569B2 (en) 2004-09-24 2007-10-23 Hoff Hoffmann-La Roche Inc. Tricycles, their manufacture and use as pharmaceutical agents
US20060142247A1 (en) * 2004-12-17 2006-06-29 Guy Georges Tricyclic heterocycles
US20060235013A1 (en) * 2005-04-14 2006-10-19 Guy Georges Tricyclic azole derivatives
MX2007012477A (es) * 2005-04-14 2007-11-08 Hoffmann La Roche Derivados de aminopirazol, su fabricacion y uso como agentes farmaceuticos.
KR20080063833A (ko) * 2005-12-15 2008-07-07 에프. 호프만-라 로슈 아게 트리시클릭 락탐 유도체, 이의 제조 및 약학적 제제로서의용도
MX2008011860A (es) * 2006-03-23 2008-09-30 Hoffmann La Roche Derivados de indazol substituidos, su manufactura y uso como agentes farmaceuticos.
WO2008063888A2 (en) 2006-11-22 2008-05-29 Plexxikon, Inc. Compounds modulating c-fms and/or c-kit activity and uses therefor
NZ582772A (en) 2007-07-17 2012-06-29 Plexxikon Inc Compounds and methods for kinase modulation, and indications therefor
SG173178A1 (en) 2009-04-03 2011-09-29 Hoffmann La Roche Propane- i-sulfonic acid {3- [5- (4 -chloro-phenyl) -1h-pyrrolo [2, 3-b] pyridine-3-carbonyl] -2, 4-difluoro-pheny l } -amide compositions and uses thereof
US8329724B2 (en) 2009-08-03 2012-12-11 Hoffmann-La Roche Inc. Process for the manufacture of pharmaceutically active compounds
CA2780190C (en) 2009-11-06 2020-05-05 Plexxikon, Inc. Compounds and methods for kinase modulation, and indications therefor
US9624213B2 (en) 2011-02-07 2017-04-18 Plexxikon Inc. Compounds and methods for kinase modulation, and indications therefor
AR085279A1 (es) 2011-02-21 2013-09-18 Plexxikon Inc Formas solidas de {3-[5-(4-cloro-fenil)-1h-pirrolo[2,3-b]piridina-3-carbonil]-2,4-difluor-fenil}-amida del acido propano-1-sulfonico
US9150570B2 (en) 2012-05-31 2015-10-06 Plexxikon Inc. Synthesis of heterocyclic compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL147842B1 (en) * 1984-05-12 1989-08-31 Method of obtaining novel pyroisobenzimidazoles
DE3445669A1 (de) * 1984-12-14 1986-06-19 Boehringer Mannheim Gmbh, 6800 Mannheim Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3501497A1 (de) * 1985-01-18 1986-07-24 Boehringer Mannheim Gmbh, 6800 Mannheim Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte
DE3531678A1 (de) * 1985-09-05 1987-03-12 Boehringer Mannheim Gmbh Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
DD267047A5 (de) 1989-04-19
JPS63162692A (ja) 1988-07-06
KR880007536A (ko) 1988-08-27
PT86331B (pt) 1990-11-07
EP0271040A3 (de) 1989-11-02
DE3642315A1 (de) 1988-06-23
US4863945A (en) 1989-09-05
AU8245087A (en) 1988-06-16
HU200339B (en) 1990-05-28
IL84589A0 (en) 1988-04-29
DK650187D0 (da) 1987-12-10
FI875438A0 (fi) 1987-12-10
ZA879166B (en) 1988-06-14
EP0271040A2 (de) 1988-06-15
FI875438A (fi) 1988-06-12
PT86331A (de) 1988-01-01
HUT47278A (en) 1989-02-28

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Legal Events

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AHB Application shelved due to non-payment