DK633989A - Laegemiddelforstadier til 3,4-hydroxy-benzoyloxypropanolaminer og deres anvendelse - Google Patents

Laegemiddelforstadier til 3,4-hydroxy-benzoyloxypropanolaminer og deres anvendelse Download PDF

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Publication number
DK633989A
DK633989A DK633989A DK633989A DK633989A DK 633989 A DK633989 A DK 633989A DK 633989 A DK633989 A DK 633989A DK 633989 A DK633989 A DK 633989A DK 633989 A DK633989 A DK 633989A
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DK
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Prior art keywords
straight
preceditions
benzoyloxypropanolamines
hydroxy
pharmaceutical
Prior art date
Application number
DK633989A
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English (en)
Other versions
DK633989D0 (da
Inventor
Ghanshyam Patil
William L Matier
Khuong H A Mai
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of DK633989D0 publication Critical patent/DK633989D0/da
Publication of DK633989A publication Critical patent/DK633989A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/06Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
    • C07C275/14Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/34Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/35Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/36Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK633989A 1988-12-15 1989-12-14 Laegemiddelforstadier til 3,4-hydroxy-benzoyloxypropanolaminer og deres anvendelse DK633989A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/285,006 US4897417A (en) 1988-12-15 1988-12-15 Prodrugs of 3,4-hydroxy benzoyloxypropanolamines

Publications (2)

Publication Number Publication Date
DK633989D0 DK633989D0 (da) 1989-12-14
DK633989A true DK633989A (da) 1990-06-16

Family

ID=23092341

Family Applications (1)

Application Number Title Priority Date Filing Date
DK633989A DK633989A (da) 1988-12-15 1989-12-14 Laegemiddelforstadier til 3,4-hydroxy-benzoyloxypropanolaminer og deres anvendelse

Country Status (16)

Country Link
US (1) US4897417A (da)
EP (1) EP0373590B1 (da)
JP (1) JPH0653714B2 (da)
AT (1) ATE102182T1 (da)
AU (1) AU619367B2 (da)
CA (1) CA2005373A1 (da)
DE (1) DE68913462T2 (da)
DK (1) DK633989A (da)
FI (1) FI895977A0 (da)
HU (1) HU203222B (da)
IL (1) IL92649A0 (da)
NO (1) NO895041L (da)
NZ (1) NZ231752A (da)
PT (1) PT92589B (da)
RU (1) RU1795966C (da)
ZA (1) ZA899619B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4935422A (en) * 1988-12-15 1990-06-19 E. I. Du Pont De Nemours And Company Acyloxypropanolamines
US4966914A (en) * 1988-12-15 1990-10-30 E. I. Du Pont De Nemours And Company Oculoselective beta-blockers as antiglaucoma agents
US5536749A (en) * 1994-10-13 1996-07-16 Sl Pharmaceuticals, Inc. Method for attenuation of sympathetic nervous system activity or onset of migraine by selectively metabolized beta-blocking agents
US6765019B1 (en) * 1999-05-06 2004-07-20 University Of Kentucky Research Foundation Permeable, water soluble, non-irritating prodrugs of chemotherapeutic agents with oxaalkanoic acids
WO2005115375A1 (en) * 2004-05-25 2005-12-08 Othera Pharmaceuticals, Inc. Oculoselective drugs and prodrugs
DK2114386T3 (da) 2007-01-29 2013-03-18 Vlife Sciences Technologies Pvt Ltd Farmaceutisk sammensætning til behandling af diabeteskomplikationer
US20110136898A1 (en) * 2008-08-05 2011-06-09 University College Cork, National University Of Ireland, Cork Treatment of retinal degeneration
CN104387265B (zh) * 2014-10-30 2016-10-26 盐城师范学院 一种4,5-二羟基-2-甲基苯甲酸的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4195085A (en) * 1975-09-26 1980-03-25 Merck & Co., Inc. Compositions and methods for treating glaucoma by the topical administration of t-butylamino-3-(4-morpholino-1,2,5-thiadiazol-3-yloxy-2-phopanol hydrogen maleate
US4405642A (en) * 1980-11-28 1983-09-20 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4402974A (en) * 1981-06-23 1983-09-06 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
US4455317A (en) * 1981-06-23 1984-06-19 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
US4582855A (en) * 1981-11-12 1986-04-15 American Hospital Supply Corporation Aromatic and esters of hydroxypropylamines
EP0105838B1 (en) * 1982-09-30 1989-06-21 William John Louis 3-aminopropoxyphenyl derivatives, their preparation and pharmaceutical compositions containing them
US4579867A (en) * 1984-04-09 1986-04-01 American Hospital Supply Corporation Stable pharmaceutical compositions of short-acting β-adrenergic receptor blocking agents

Also Published As

Publication number Publication date
EP0373590A2 (en) 1990-06-20
NO895041D0 (no) 1989-12-14
DE68913462D1 (de) 1994-04-07
HU896641D0 (en) 1990-02-28
US4897417A (en) 1990-01-30
AU619367B2 (en) 1992-01-23
DK633989D0 (da) 1989-12-14
FI895977A0 (fi) 1989-12-14
AU4679989A (en) 1990-06-21
NZ231752A (en) 1991-03-26
JPH0653714B2 (ja) 1994-07-20
EP0373590A3 (en) 1991-03-27
RU1795966C (ru) 1993-02-15
HU203222B (en) 1991-06-28
ATE102182T1 (de) 1994-03-15
ZA899619B (en) 1991-08-28
EP0373590B1 (en) 1994-03-02
IL92649A0 (en) 1990-08-31
PT92589A (pt) 1990-06-29
PT92589B (pt) 1995-09-12
DE68913462T2 (de) 1994-07-14
JPH02258751A (ja) 1990-10-19
NO895041L (no) 1990-06-18
HUT53065A (en) 1990-09-28
CA2005373A1 (en) 1990-06-15

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment