DK622189D0 - PROTEIN INCLUDED IN THE SYNTHESIS OF BETA-LACTAM COMPOUNDS AND GENES CODING THEREOF - Google Patents

PROTEIN INCLUDED IN THE SYNTHESIS OF BETA-LACTAM COMPOUNDS AND GENES CODING THEREOF

Info

Publication number
DK622189D0
DK622189D0 DK622189A DK622189A DK622189D0 DK 622189 D0 DK622189 D0 DK 622189D0 DK 622189 A DK622189 A DK 622189A DK 622189 A DK622189 A DK 622189A DK 622189 D0 DK622189 D0 DK 622189D0
Authority
DK
Denmark
Prior art keywords
beta
synthesis
genes coding
lactam compounds
protein included
Prior art date
Application number
DK622189A
Other languages
Danish (da)
Other versions
DK175769B1 (en
DK622189A (en
Inventor
Franz Knauseder
Ernst Leitner
Norbert Palma
Gerhard Weber
Original Assignee
Biochemie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AT92288A external-priority patent/AT390268B/en
Priority claimed from AT180688A external-priority patent/AT391141B/en
Priority claimed from AT220188A external-priority patent/AT391142B/en
Application filed by Biochemie Gmbh filed Critical Biochemie Gmbh
Publication of DK622189D0 publication Critical patent/DK622189D0/en
Publication of DK622189A publication Critical patent/DK622189A/en
Application granted granted Critical
Publication of DK175769B1 publication Critical patent/DK175769B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C12N9/84—Penicillin amidase (3.5.1.11)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)

Abstract

Gene and gene product of a key enzyme which is novel because of its structure and multivalent functionality, and catalyses the last stage of the biosynthesis of penicillin G and penicillin V.
DK198906221A 1988-04-08 1989-12-08 DNA sequence in purified and isolated form encoding the enzyme penicillin acetyltransferase, protein encoding the DNA sequence, vector, ........... DK175769B1 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
AT92288 1988-04-08
AT92288A AT390268B (en) 1988-04-08 1988-04-08 DNA from Penicillium chrysogenum and protein for which this DNA codes
AT180688A AT391141B (en) 1988-07-13 1988-07-13 DNA which codes for the enzyme penicillin acyltransferase (PAT)
AT180688 1988-07-13
AT220188 1988-09-08
AT220188A AT391142B (en) 1988-09-08 1988-09-08 DNA from Penicillium chrysogenum
PCT/EP1989/000374 WO1989009821A1 (en) 1988-04-08 1989-04-07 GENE AND GENE PRODUCT FOR PREPARING beta-LACTAM COMPOUNDS
EP8900374 1989-04-07

Publications (3)

Publication Number Publication Date
DK622189D0 true DK622189D0 (en) 1989-12-08
DK622189A DK622189A (en) 1990-02-02
DK175769B1 DK175769B1 (en) 2005-02-14

Family

ID=27146880

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198906221A DK175769B1 (en) 1988-04-08 1989-12-08 DNA sequence in purified and isolated form encoding the enzyme penicillin acetyltransferase, protein encoding the DNA sequence, vector, ...........

Country Status (12)

Country Link
EP (1) EP0336446B1 (en)
JP (1) JPH0767387B2 (en)
KR (1) KR900700610A (en)
AT (1) ATE105860T1 (en)
AU (1) AU637317B2 (en)
DE (1) DE58907667D1 (en)
DK (1) DK175769B1 (en)
ES (1) ES2054916T3 (en)
FI (1) FI103053B (en)
HK (1) HK99996A (en)
HU (1) HU208845B (en)
WO (1) WO1989009821A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5747285A (en) * 1989-02-01 1998-05-05 Gist-Brocades, Nv. DNA comprising regulatory regions from gene y of penicillium chrysogenum
IL95766A (en) * 1989-09-27 1996-12-05 Lilly Co Eli Recombinant DNA expression vectors and DNA compounds that encode acyltransferase activity of aspergillus
US5882879A (en) * 1990-02-28 1999-03-16 Gist-Brocades, N.V. Method for influencing β-lactam antibiotic production and for isolation of large quantities of ACV synthetase
US5168048A (en) * 1990-04-18 1992-12-01 Gist-Brocades Nv Penicillin G acylase, a gene encoding the same and a method for the production of this enzyme
EP0914463A2 (en) * 1996-07-16 1999-05-12 Gist-Brocades B.V. NOVEL PROCESS FOR THE PREPARATION OF CEPHALOSPORINS USING $i(ACREMONIUM CHRYSOGENUM)
CN101142312A (en) * 2005-02-24 2008-03-12 帝斯曼知识产权资产管理有限公司 Altered isopenicillin-n acyltransferase polypeptides and related polynucleotides

Also Published As

Publication number Publication date
WO1989009821A1 (en) 1989-10-19
DK175769B1 (en) 2005-02-14
KR900700610A (en) 1990-08-16
EP0336446A1 (en) 1989-10-11
EP0336446B1 (en) 1994-05-18
HUT52156A (en) 1990-06-28
JPH02503750A (en) 1990-11-08
ATE105860T1 (en) 1994-06-15
ES2054916T3 (en) 1994-08-16
AU637317B2 (en) 1993-05-27
JPH0767387B2 (en) 1995-07-26
HU208845B (en) 1994-01-28
HU892092D0 (en) 1990-02-28
FI103053B1 (en) 1999-04-15
FI895846A0 (en) 1989-12-07
DE58907667D1 (en) 1994-06-23
AU3362689A (en) 1989-11-03
DK622189A (en) 1990-02-02
FI103053B (en) 1999-04-15
HK99996A (en) 1996-06-14

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment
AHB Application shelved due to non-payment
PUP Patent expired