DK619989A - Dipeptidderivater, deres fremstilling og anvendelse som laegemidler - Google Patents

Dipeptidderivater, deres fremstilling og anvendelse som laegemidler Download PDF

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Publication number
DK619989A
DK619989A DK619989A DK619989A DK619989A DK 619989 A DK619989 A DK 619989A DK 619989 A DK619989 A DK 619989A DK 619989 A DK619989 A DK 619989A DK 619989 A DK619989 A DK 619989A
Authority
DK
Denmark
Prior art keywords
pharmaceuticals
preparation
dipeptide derivatives
dipeptide
derivatives
Prior art date
Application number
DK619989A
Other languages
Danish (da)
English (en)
Other versions
DK619989D0 (da
Inventor
Wolf-Ulrich Nickel
Hansjoerg Urbach
Dieter Ruppert
Bernward Schoelkens
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK619989D0 publication Critical patent/DK619989D0/da
Publication of DK619989A publication Critical patent/DK619989A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06078Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/0606Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK619989A 1988-12-10 1989-12-08 Dipeptidderivater, deres fremstilling og anvendelse som laegemidler DK619989A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3841732A DE3841732A1 (de) 1988-12-10 1988-12-10 Dipeptid-derivate mit enzym-inhibitorischer wirkung

Publications (2)

Publication Number Publication Date
DK619989D0 DK619989D0 (da) 1989-12-08
DK619989A true DK619989A (da) 1990-06-11

Family

ID=6368937

Family Applications (1)

Application Number Title Priority Date Filing Date
DK619989A DK619989A (da) 1988-12-10 1989-12-08 Dipeptidderivater, deres fremstilling og anvendelse som laegemidler

Country Status (15)

Country Link
EP (1) EP0373497A3 (pt)
JP (1) JPH02202899A (pt)
KR (1) KR900009687A (pt)
CN (1) CN1043132A (pt)
AU (1) AU634188B2 (pt)
DD (1) DD290895A5 (pt)
DE (1) DE3841732A1 (pt)
DK (1) DK619989A (pt)
FI (1) FI895874A0 (pt)
HU (1) HU206371B (pt)
IL (1) IL92618A0 (pt)
NO (1) NO894944L (pt)
PT (1) PT92496A (pt)
RU (1) RU1836381C (pt)
ZA (1) ZA899407B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0546115A1 (en) * 1990-08-24 1993-06-16 The Upjohn Company Peptides containing amino-polyols as transition-state mimics
US6313094B1 (en) 1990-12-11 2001-11-06 Japan Energy Corporation β-amino-α-hydroxycarboxylic acid derivatives and HIV protease inhibitors
PL294866A1 (en) * 1991-06-21 1993-05-31 Hoechst Ag Method of obtaining novel rennin redtarding heterocyclic compounds
PL294870A1 (pt) * 1991-06-21 1993-02-08 Hoechst Ag
US6969731B1 (en) 1999-02-19 2005-11-29 The University of Illinois, Board of Trustees Protease inhibitors that overcome drug resistance
AU3369200A (en) * 1999-02-19 2000-09-04 Board Of Trustees Of The University Of Illinois, The Protease inhibitors that overcome drug resistance
DE10029077A1 (de) * 2000-06-13 2001-12-20 Bayer Ag Thiazolylsubstituierte Heterocyclen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3627877A1 (de) * 1986-07-30 1988-02-04 Hoechst Ag Renin-hemmende di- und tripeptide, verfahren zu deren herstellung, diese enthaltende mittel und ihre verwendung
SE8605573D0 (sv) * 1986-12-29 1986-12-29 Haessle Ab Novel compounds

Also Published As

Publication number Publication date
ZA899407B (en) 1990-08-29
PT92496A (pt) 1990-06-29
HU896475D0 (en) 1990-02-28
FI895874A0 (fi) 1989-12-08
IL92618A0 (en) 1990-08-31
RU1836381C (ru) 1993-08-23
DD290895A5 (de) 1991-06-13
CN1043132A (zh) 1990-06-20
DE3841732A1 (de) 1990-06-13
DK619989D0 (da) 1989-12-08
HU206371B (en) 1992-10-28
AU4600389A (en) 1990-08-09
NO894944D0 (no) 1989-12-08
EP0373497A3 (de) 1991-04-10
JPH02202899A (ja) 1990-08-10
KR900009687A (ko) 1990-07-05
NO894944L (no) 1990-06-11
HUT54176A (en) 1991-01-28
EP0373497A2 (de) 1990-06-20
AU634188B2 (en) 1993-02-18

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