DK594183A - Cephemderivater, eller deres fysiologisk acceptable syreadditionssalte, deres fremstilling og anvendelse - Google Patents

Cephemderivater, eller deres fysiologisk acceptable syreadditionssalte, deres fremstilling og anvendelse Download PDF

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Publication number
DK594183A
DK594183A DK594183A DK594183A DK594183A DK 594183 A DK594183 A DK 594183A DK 594183 A DK594183 A DK 594183A DK 594183 A DK594183 A DK 594183A DK 594183 A DK594183 A DK 594183A
Authority
DK
Denmark
Prior art keywords
denotes
acid addition
see diagramm
radical
acceptable acid
Prior art date
Application number
DK594183A
Other languages
Danish (da)
English (en)
Other versions
DK594183D0 (da
Inventor
Walter Duerckheimer
Rudolf Lattrell
Karl Seeger
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK594183D0 publication Critical patent/DK594183D0/da
Publication of DK594183A publication Critical patent/DK594183A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Control Of Electric Motors In General (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Fats And Perfumes (AREA)
DK594183A 1982-12-23 1983-12-22 Cephemderivater, eller deres fysiologisk acceptable syreadditionssalte, deres fremstilling og anvendelse DK594183A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823247613 DE3247613A1 (de) 1982-12-23 1982-12-23 Cephalosporinderivate und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
DK594183D0 DK594183D0 (da) 1983-12-22
DK594183A true DK594183A (da) 1984-06-24

Family

ID=6181484

Family Applications (1)

Application Number Title Priority Date Filing Date
DK594183A DK594183A (da) 1982-12-23 1983-12-22 Cephemderivater, eller deres fysiologisk acceptable syreadditionssalte, deres fremstilling og anvendelse

Country Status (20)

Country Link
EP (1) EP0111934B1 (ko)
JP (1) JPS59130295A (ko)
KR (1) KR840007014A (ko)
AT (1) ATE36534T1 (ko)
AU (1) AU2281083A (ko)
CA (1) CA1235689A (ko)
CS (1) CS248714B2 (ko)
DE (2) DE3247613A1 (ko)
DK (1) DK594183A (ko)
ES (1) ES528248A0 (ko)
FI (1) FI834711A (ko)
GR (1) GR79456B (ko)
HU (1) HU189793B (ko)
IL (1) IL70521A0 (ko)
MA (1) MA19984A1 (ko)
NO (1) NO834774L (ko)
NZ (1) NZ206660A (ko)
PH (1) PH21026A (ko)
PT (1) PT77878B (ko)
ZA (1) ZA839537B (ko)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60169486A (ja) * 1984-02-10 1985-09-02 Yamanouchi Pharmaceut Co Ltd ７−アミノ−３−置換メチル−３−セフエム−４−カルボン酸およびその低級アルキルシリル誘導体の製造法
ATE114657T1 (de) * 1985-12-26 1994-12-15 Eisai Co Ltd Cephalosporin-verbindungen.
IL84128A (en) * 1986-10-13 1992-12-01 Eisai Co Ltd 3-propenylcephem derivatives, their preparation and pharmaceutical compositions containing them
US4929612A (en) * 1987-04-17 1990-05-29 Eisai Co., Ltd. Thiadiazolylacetamide cephem derivatives
DE3910421A1 (de) * 1989-03-31 1990-10-04 Hoechst Ag Polare cephalosporinderivate und verfahren zu ihrer herstellung
WO2013036783A2 (en) 2011-09-09 2013-03-14 Cubist Pharmaceuticals, Inc. Methods for treating intrapulmonary infections
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
KR102329764B1 (ko) 2013-03-15 2021-11-23 머크 샤프 앤드 돔 코포레이션 세프톨로잔 항균성 조성물
US20140274991A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Ceftolozane pharmaceutical compositions
WO2015035376A2 (en) 2013-09-09 2015-03-12 Calixa Therapeutics, Inc. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US8906898B1 (en) 2013-09-27 2014-12-09 Calixa Therapeutics, Inc. Solid forms of ceftolozane

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU536842B2 (en) * 1978-12-29 1984-05-24 Fujisawa Pharmaceutical Co., Ltd. Cephalosporin antibiotics
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
FI834711A (fi) 1984-06-24
PT77878A (de) 1984-01-01
IL70521A0 (en) 1984-03-30
ES8406493A1 (es) 1984-08-01
PH21026A (en) 1987-06-30
HUT34035A (en) 1985-01-28
KR840007014A (ko) 1984-12-04
CA1235689A (en) 1988-04-26
FI834711A0 (fi) 1983-12-21
CS248714B2 (en) 1987-02-12
EP0111934A3 (en) 1985-05-15
DE3247613A1 (de) 1984-07-05
ATE36534T1 (de) 1988-09-15
EP0111934B1 (de) 1988-08-17
GR79456B (ko) 1984-10-30
ZA839537B (en) 1984-08-29
DK594183D0 (da) 1983-12-22
AU2281083A (en) 1984-06-28
NO834774L (no) 1984-06-25
MA19984A1 (fr) 1984-07-01
NZ206660A (en) 1987-07-31
JPS59130295A (ja) 1984-07-26
DE3377714D1 (en) 1988-09-22
HU189793B (en) 1986-07-28
ES528248A0 (es) 1984-08-01
EP0111934A2 (de) 1984-06-27
PT77878B (de) 1986-04-21

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FI834710A (fi) Kefalosporinderivat och foerfarande foer deras framstaellning.
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Legal Events

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ATS Application withdrawn