DK58688A - Alkyl(heterocyclymethyl)phenethylamin-forbindelser, farmaceutiske praeparater indeholdende de alkylsulfonylaminosubstituerede forbindelser og anvendelse af disse til fremstilling af et laegemiddel til forhindring eller reduktion af hjertearrytmier - Google Patents

Alkyl(heterocyclymethyl)phenethylamin-forbindelser, farmaceutiske praeparater indeholdende de alkylsulfonylaminosubstituerede forbindelser og anvendelse af disse til fremstilling af et laegemiddel til forhindring eller reduktion af hjertearrytmier

Info

Publication number
DK58688A
DK58688A DK058688A DK58688A DK58688A DK 58688 A DK58688 A DK 58688A DK 058688 A DK058688 A DK 058688A DK 58688 A DK58688 A DK 58688A DK 58688 A DK58688 A DK 58688A
Authority
DK
Denmark
Prior art keywords
preparation
alkyl
sulphonylaminos
heterocyclylmethyl
product
Prior art date
Application number
DK058688A
Other languages
English (en)
Other versions
DK168382B1 (da
DK58688D0 (da
Inventor
Peter Edward Cross
John Edmund Arrowsmith
Geoffrey Noel Thomas
Roger Peter Dickinson
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878702789A external-priority patent/GB8702789D0/en
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of DK58688D0 publication Critical patent/DK58688D0/da
Publication of DK58688A publication Critical patent/DK58688A/da
Application granted granted Critical
Publication of DK168382B1 publication Critical patent/DK168382B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/58—Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK058688A 1987-02-07 1988-02-05 Bis-(alkylsulfonylamino)-substituerede alkyl(heterocyclylmethyl)phenethylamin-forbindelser, farmaceutiske præparater indeholdende disse, forbindelserne til anvendelse som lægemidler, anvendelse af forbindelserne til fremstilling af lægemidler til forhindring eller reduktion af hjertearytmier og alkyl(heterocyclylmethyl)phenethylamin-forbindelser til anvendelse som mellemprodukter DK168382B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB878702789A GB8702789D0 (en) 1987-02-07 1987-02-07 Antiarrhythmic agents
GB8702789 1987-02-07
CA000567187A CA1298840C (en) 1987-02-07 1988-05-19 Antiarrhythmic agents
CA567187 1988-05-19

Publications (3)

Publication Number Publication Date
DK58688D0 DK58688D0 (da) 1988-02-05
DK58688A true DK58688A (da) 1988-08-08
DK168382B1 DK168382B1 (da) 1994-03-21

Family

ID=25671903

Family Applications (1)

Application Number Title Priority Date Filing Date
DK058688A DK168382B1 (da) 1987-02-07 1988-02-05 Bis-(alkylsulfonylamino)-substituerede alkyl(heterocyclylmethyl)phenethylamin-forbindelser, farmaceutiske præparater indeholdende disse, forbindelserne til anvendelse som lægemidler, anvendelse af forbindelserne til fremstilling af lægemidler til forhindring eller reduktion af hjertearytmier og alkyl(heterocyclylmethyl)phenethylamin-forbindelser til anvendelse som mellemprodukter

Country Status (8)

Country Link
US (3) US4956382A (da)
EP (1) EP0281254B1 (da)
JP (1) JPH0625122B2 (da)
AU (1) AU586139B1 (da)
CA (1) CA1298840C (da)
DK (1) DK168382B1 (da)
ES (1) ES2013313B3 (da)
IE (1) IE60349B1 (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5202336A (en) * 1986-09-24 1993-04-13 Bayer Aktiengesellschaft Antiflammatory quinolin methoxy phenylsulphonamides
US4956382A (en) * 1987-02-07 1990-09-11 Pfizer Inc. Sulfonamide anti-arrhythmic agents
US5166209A (en) * 1989-04-21 1992-11-24 Burroughs Wellcome Co. Pharmacologically active compounds
US5112824A (en) * 1989-12-08 1992-05-12 Merck & Co., Inc. Benzofuran compounds as class III antiarrhythmic agents
US5032598A (en) * 1989-12-08 1991-07-16 Merck & Co., Inc. Nitrogens containing heterocyclic compounds as class III antiarrhythmic agents
US5032604A (en) * 1989-12-08 1991-07-16 Merck & Co., Inc. Class III antiarrhythmic agents
US5215989A (en) * 1989-12-08 1993-06-01 Merck & Co., Inc. Nitrogen-containing heterocyclic compounds as class III antiarrhythmic agents
AU6977391A (en) * 1989-12-11 1991-07-18 American Home Products Corporation N-heteroaralkyl-substituted 1-aryloxy-2-propanolamine and propylamine derivatives possessing class iii antiarrhythmic activity
US5084463A (en) * 1989-12-11 1992-01-28 American Home Products Corporation N-quinolinyl alkyl-substituted 1-aryloxy-2-propanolamine and propylamine derivatives possessing class III antiarrhythmic activity
US5089514A (en) * 1990-06-14 1992-02-18 Pfizer Inc. 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents
US5189179A (en) * 1990-08-29 1993-02-23 Merrell Dow Pharmaceuticals Inc. Serotonin 5ht1a agonists
GB9021056D0 (en) * 1990-09-27 1990-11-07 Pfizer Ltd Antiarrhythmic agents
FR2695930B1 (fr) * 1992-09-22 1994-12-23 Sanofi Elf Dérivé du 2-éthyl benzo[b]thiophène, son procédé de préparation et son utilisation comme intermédiaire de synthèse.
US5382587A (en) * 1993-06-30 1995-01-17 Merck & Co., Inc. Spirocycles
US5403846A (en) * 1993-11-22 1995-04-04 Merck & Co., Inc. Spirocycles
US5439914A (en) * 1994-02-18 1995-08-08 Merck & Co., Inc. Spirocycles
US6902738B2 (en) * 1994-05-02 2005-06-07 Josman Laboratories, Inc. Topical oral dosage forms containing bismuth compounds
KR960007566A (ko) * 1994-08-19 1996-03-22 김정규 신규한 퀴놀릴아민 유도체, 그의 제조방법 및 항부정맥제로서의 용도
DE19547263C2 (de) * 1995-12-07 1999-04-29 Cardiotec Inc Amidinohydrazone vom Benzo[b]furan abgeleiteter Ketone, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
GB9711220D0 (en) * 1997-05-30 1997-07-23 Isis Innovation Antiarrhythmic agents
US6083991A (en) 1997-06-04 2000-07-04 University Of Florida Research Foundation, Inc. Anti-arrhythmic composition and methods of treatment
FR2804429B1 (fr) * 2000-01-31 2003-05-09 Adir Nouveaux derives de 4-sulfonamides piperidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6660858B2 (en) 2001-03-28 2003-12-09 Lion Bioscience Ag 2-aminobenzoxazole derivatives and combinatorial libraries thereof
US9745519B2 (en) 2012-08-22 2017-08-29 Kellogg Brown & Root Llc FCC process using a modified catalyst

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1520801A (en) * 1975-01-16 1978-08-09 Lafon Labor Benzodioxanyl and benzofuranylmethylamines
DE2833140A1 (de) * 1978-07-28 1980-02-07 Boehringer Sohn Ingelheim Neue n-substituierte heterocyclen
IT1154888B (it) * 1980-11-12 1987-01-21 Menarini Sas Derivati del benzofurano 2-sostituiti e relativi metodi di preparazione
JPS6145A (ja) * 1984-06-09 1986-01-06 Kaken Pharmaceut Co Ltd Ｎ‐（４‐ｔｅｒｔ‐ブチルベンジル）‐Ｎ‐メチル‐１‐ナフチルメチルアミンおよびそれを有効成分とする抗真菌剤
US4581457A (en) * 1984-09-21 1986-04-08 American Home Products Corporation Heterocyclic sulfonamides
GB8603120D0 (en) * 1986-02-07 1986-03-12 Pfizer Ltd Anti-dysrhythmia agents
GB8609331D0 (en) * 1986-04-16 1986-05-21 Pfizer Ltd Anti-arrythmia agents
FR2601950B1 (fr) * 1986-07-22 1988-11-10 Cerm Cent Europ Rech Mauvernay N,n-dimethyl-n'-benzoyl-n' ((2,3-dihydro) benzofuran-2-yl-methyl) 1,3-propanediamine, preparation et compositions pharmaceutiques les contenant
DE3632329A1 (de) * 1986-09-24 1988-03-31 Bayer Ag Substituierte phenylsulfonamide
US4956382A (en) * 1987-02-07 1990-09-11 Pfizer Inc. Sulfonamide anti-arrhythmic agents

Also Published As

Publication number Publication date
JPH0625122B2 (ja) 1994-04-06
DK168382B1 (da) 1994-03-21
CA1298840C (en) 1992-04-14
IE60349B1 (en) 1994-06-29
US4956382A (en) 1990-09-11
DK58688D0 (da) 1988-02-05
AU586139B1 (en) 1989-06-29
US5055473A (en) 1991-10-08
JPS63201167A (ja) 1988-08-19
EP0281254A1 (en) 1988-09-07
ES2013313B3 (es) 1990-05-01
EP0281254B1 (en) 1990-01-17
IE880322L (en) 1988-08-07
US5158964A (en) 1992-10-27

Similar Documents

Publication Publication Date Title
DK58688A (da) Alkyl(heterocyclymethyl)phenethylamin-forbindelser, farmaceutiske praeparater indeholdende de alkylsulfonylaminosubstituerede forbindelser og anvendelse af disse til fremstilling af et laegemiddel til forhindring eller reduktion af hjertearrytmier
DK213085A (da) Aminotetralinderivater, laegemidler indeholdende disse og fremgangsmaade til forbindelsernes fremstilling
DK362787D0 (da) Benzensulfonamido-indanylforbindelser, laegemidler indeholdende disse forbindelser og fremgangsmaade til deres fremstilling
DK170785A (da) 4-substituerede-piperazin-2-carboxylsyre-derivater og farmaceutisk acceptable salte deraf, fremgangsmaade til fremstilling af saadanne forbindelser og farmaceutiske praeparater indeholdende disse
DK586185A (da) Carbostyrilforbindelser, fremgangsmaade til fremstilling heraf og farmaceutisk praeparat indeholdende en saadan forbindelse
DK206987A (da) Hidtil ukendte diphosphonsyreforbindelser, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende disse forbindelser
DK181586A (da) 2,5-diaryltetrahydrofuran, farmaceutisk praeparat indeholdendeen saadan forbindelse og fremgangsmaade til fremstilling af en saadan forbindelse
NO883054D0 (no) Fremgangsmaate for fremstilling av farmasoeytisk preparat inneholdende somatostatinanaloger.
DK276189D0 (da) Polypeptidforbindelser, fremgangsmaader til fremstilling heraf farmaceutiske midler indeholdende disse
DK280282A (da) Fremgangsmaade til fremstilling af farmaceutiske praeparater indeholdende ergotalkaloider
DK127588A (da) Beta-aminoethylsubstituerede phenylforbindelser, farmaceutiske praeparater indeholdende samme og fremgangsmaader til fremstilling af saadanne forbindelser
DK538885D0 (da) Imidazolylalkylguanidinderivater, fremgangsmaade til fremstilling herafsamt laegemidler indeholdende disse forbindelser
DK183986A (da) Cyklopentylaetere, fremgangsmaade til fremstilling deraf og laegemiddelpraeparat indeholdende saadanne forbindelser
DK102990A (da) Thieno-triazolodiazepinderivater, fremgangsmaade til fremstilling af saadanne forbindelser og laegemiddel indeholdende disse
DK121786D0 (da) Fremgangsmaade til fremstilling af et kornformigt produkt, der indeholder natriumtriphosphat
DK457787A (da) Sulfonamidoethylforbindelser, laegemidler indeholdende disse forbindelser og fremgangsmaade til deres fremstilling
DK612788D0 (da) Alkoxyderivater af ginkolider, fremgangsmaade til fremstilling heraf og farmaceutiske praeparater indeholdende saadanne forbindelser
DK187989D0 (da) Substituerede propanaminer, fremgangsmaade til fremstilling heraf og laegemidler indeholdende saadanne forbindelser
DK607388D0 (da) Polynukleotider, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende saadanne forbindelser
DK493988D0 (da) 4-oxo-3-quinolincarboxylsyrer, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende disse forbindelser
DK597184A (da) Substituerede spiro-pyridinderivater, farmaceutiske praeparater indeholdende dem og fremgangsmaade til fremstilling af saadanne forbindelser
DK123488A (da) 2-oxa-isocephemforbindelser, praeparater indeholdende dem, og fremgangsmaader til fremstilling af dem
DK93385D0 (da) 3-amino-1-(4,5,6,7-tetrahydro-benzothiazolyl)-2-pyrazoliner, fremgangsmaade til fremstilling af disse forbindelser og farmaceutiske praeparater indeholdende disse forbindelser
DK106287D0 (da) Glycero-3(2)-phospho-l-serin-derivater og salte deraf, fremgangsmaade til fremstilling af saadanne forbindelser og farmaceutiske praeparater indeholdende disse
DK164453C (da) Dibenzooeb,daathiopyran-6-carboxylsyreforbindelser, fremgangsmaade til fremstilling heraf og farmaceutiske praeparater indeholdende disse forbindelser

Legal Events

Date Code Title Description
PBP Patent lapsed

Country of ref document: DK