DK566176A - Fremgangsmade til fremstilling af 4-androsten-3,17-dionderivater - Google Patents

Fremgangsmade til fremstilling af 4-androsten-3,17-dionderivater

Info

Publication number
DK566176A
DK566176A DK566176A DK566176A DK566176A DK 566176 A DK566176 A DK 566176A DK 566176 A DK566176 A DK 566176A DK 566176 A DK566176 A DK 566176A DK 566176 A DK566176 A DK 566176A
Authority
DK
Denmark
Prior art keywords
androstene
procedure
preparation
dione derivatives
dione
Prior art date
Application number
DK566176A
Other languages
English (en)
Other versions
DK139267C (da
DK139267B (da
Inventor
A Weber
M Kennecke
R Mueller
U Eder
R Wiechert
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK566176A publication Critical patent/DK566176A/da
Priority to DK109078A priority Critical patent/DK109078A/da
Publication of DK139267B publication Critical patent/DK139267B/da
Application granted granted Critical
Publication of DK139267C publication Critical patent/DK139267C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
    • C07J1/004—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0048—Alkynyl derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C12P33/005—Degradation of the lateral chains at position 17
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/832—Bacillus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/84—Brevibacterium
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/863—Mycobacterium
    • Y10S435/866—Mycobacterium smegmatis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/872—Nocardia
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK566176A 1975-12-19 1976-12-16 Fremgangsmaade til fremstilling af 4-androsten-3,17-dionderivater DK139267C (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK109078A DK109078A (da) 1975-12-19 1978-03-10 Fremgangsmaade til fremstilling af 17beta-hydroxy-4-androsten-3-onderivater

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2558088A DE2558088C2 (de) 1975-12-19 1975-12-19 Verfahren zur Herstellung von 4-Androsten-3,17-dion-Derivaten

Publications (3)

Publication Number Publication Date
DK566176A true DK566176A (da) 1977-06-20
DK139267B DK139267B (da) 1979-01-22
DK139267C DK139267C (da) 1979-06-25

Family

ID=5965329

Family Applications (1)

Application Number Title Priority Date Filing Date
DK566176A DK139267C (da) 1975-12-19 1976-12-16 Fremgangsmaade til fremstilling af 4-androsten-3,17-dionderivater

Country Status (14)

Country Link
US (1) US4100027A (da)
JP (1) JPS5294493A (da)
AT (1) AT367092B (da)
BE (1) BE849557A (da)
CH (1) CH622532A5 (da)
CS (1) CS187348B2 (da)
DD (2) DD134106A5 (da)
DE (1) DE2558088C2 (da)
DK (1) DK139267C (da)
FR (1) FR2335522A1 (da)
GB (1) GB1571913A (da)
HU (1) HU183022B (da)
IE (1) IE44515B1 (da)
NL (1) NL7614024A (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4223092A (en) * 1977-10-21 1980-09-16 The Upjohn Company Process for preparing 9α-OH BN acid methyl ester
US4383947A (en) * 1981-07-24 1983-05-17 The Upjohn Company Introduction of a fluorine atom
GB2104526B (en) * 1981-07-24 1985-06-05 Upjohn Co 6-fluoro-9-hydroxyandrost-4-ene-3,17-diones and microbial preparation thereof
US5227375A (en) * 1990-02-08 1993-07-13 Endorecherche, Inc. Aromatase inhibitors
AU8779898A (en) * 1997-08-11 1999-03-01 Weider Nutrition International, Inc. Compositions and treatments to reduce side effects of administration of androgenic testosterone precursors
US6071714A (en) * 1998-03-26 2000-06-06 Forbes Medi-Tech, Inc. Process for the microbial conversion of phytosterols to androstenedione and androstadienedione
DE19827523A1 (de) 1998-06-22 1999-12-23 Jenapharm Gmbh Ungesättigte 14,15-Cyclopropano-Androstane, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate
KR100432054B1 (ko) * 2001-05-11 2004-05-17 (주)유진사이언스 스테롤로부터 4-안드로스텐-3,17-디온/안드로스타-1,4-디엔-3,17-디온으로의 뛰어난 전환능을 가지는 미생물 및 이의 제조방법
BRPI0306736B8 (pt) * 2002-01-21 2021-05-25 Akzo Nobel Nv processo para a preparação de 7alfa-metilesteróides, e, composto
DE10213371C1 (de) * 2002-03-21 2003-12-24 Schering Ag Verfahren zur Herstellung von 7alpha-Methylsteroiden
US20040010138A1 (en) * 2002-03-21 2004-01-15 Schering Ag Process for the production of 7alpha-methyl steroids
AR061892A1 (es) * 2007-07-11 2008-10-01 Consejo Nac Invest Cient Tec Un compuesto que presenta actividad antiinflamatoria y actividad antiviral, composiciones farmaceuticas que lo comprenden, un procedimiento para su obtencion y uso del mismo en el tratamiento de la queratoconjuntivitis epidemica y de la queratitis estromal herpetica

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1092145A (en) * 1964-06-02 1967-11-22 Noda Inst For Scientific Res Microbiological conversion of steroids
NL6705450A (da) * 1965-10-22 1968-10-21
US3684657A (en) * 1970-05-11 1972-08-15 Searle & Co Selective microbiological degradation of steroidal 17-alkyls
US3759791A (en) * 1970-12-10 1973-09-18 Searle & Co Selective microbiological preparation of androst-4-ene-3,17-dione

Also Published As

Publication number Publication date
HU183022B (en) 1984-04-28
JPS5294493A (en) 1977-08-09
DK139267C (da) 1979-06-25
BE849557A (fr) 1977-06-17
DD129334A5 (de) 1978-01-11
FR2335522B1 (da) 1980-07-04
CH622532A5 (da) 1981-04-15
GB1571913A (en) 1980-07-23
IE44515B1 (en) 1981-12-30
US4100027A (en) 1978-07-11
FR2335522A1 (fr) 1977-07-15
ATA935676A (de) 1981-10-15
IE44515L (en) 1977-06-19
DD134106A5 (de) 1979-02-07
NL7614024A (nl) 1977-06-21
DK139267B (da) 1979-01-22
DE2558088A1 (de) 1977-07-07
JPS615715B2 (da) 1986-02-20
AT367092B (de) 1982-05-25
DE2558088C2 (de) 1985-05-30
CS187348B2 (en) 1979-01-31

Similar Documents

Publication Publication Date Title
DK567376A (da) Fremgangsmade til fremstilling af quinazolonderivater
DK146205C (da) Analogifremgangsmaade til fremstilling af 8alfa-ergolin-i-derivater
DK545076A (da) Fremgangsmade til fremstilling af imidazolderivater
DK139267C (da) Fremgangsmaade til fremstilling af 4-androsten-3,17-dionderivater
DK324176A (da) Fremgangsmade til fremstilling af orthoaminobutyrophenonderivater
DK528976A (da) Fremgangsmade til fremstilling af indazolderivater
DK298476A (da) Fremgangsmade til fremstilling af 5-benzyl-2-oxazolidonderivater
DK137275C (da) Fremgangsmaade til fremstilling af 4-oxo-hexahydropyrazinoisoquinolinderivater
DK506075A (da) Fremgangsmade til fremstilling af ostren-3,17-dionderivater
DK565676A (da) Fremgangsmade til fremstilling af klavamderivater
DK343976A (da) Fremgangsmade til fremstilling af 5-androsten-17-on-derivater
DK551076A (da) Fremgangsmade til fremstilling af trifluormethylthio-derivater af cyproheptadin
DK140728B (da) Fremgangsmåde til fremstilling af pregnanderivater.
DK251176A (da) Fremgangsmade til fremstilling af cyklopropanolderivater
DK253676A (da) Fremgangsmade til fremstilling af cycloheptathiopenderivater
DK139269C (da) Fremgangsmaade til fremstilling af 4-androsten-3,17-dionderivater
DK142057C (da) Analogifremgangsmaade til fremstilling af 15alfa,16alfa-methylen-1,4-pregnadien-3,20-dionderivater
DK141532C (da) Fremgangsmaade til fremstilling af 21-hydroxy-16-pregnen-20-onderivater
DK498776A (da) Fremgangsmade til fremstilling af imidazolderivater
DK566276A (da) Fremgangsmade til fremstilling af androstan-3,17-dionderivater
DK562076A (da) Fremgangsmade til fremstilling af azetidinonderivater
DK62876A (da) Fremgangsmade til fremstilling af benzo-cyclohepta-thiophenderivater
DK22276A (da) Fremgangsmade til fremstilling af thiazol-5-methanolderivater
DK145759C (da) Fremgangsmaade til fremstilling af 15beta,16beta-methylen-oestren-3,17-dionderivater
DK365676A (da) Fremgangsmade til fremstilling af aminomethylbenzocycloheptenderivater

Legal Events

Date Code Title Description
PBP Patent lapsed