DK562686A - 2,2 -bi-1h-imidazoler, tautomere og farmaceutisk acceptable salte deraf, deres fremstilling og anvendelse som cardiotonika samt mellemprodukter ved fremstillingen - Google Patents
2,2 -bi-1h-imidazoler, tautomere og farmaceutisk acceptable salte deraf, deres fremstilling og anvendelse som cardiotonika samt mellemprodukter ved fremstillingenInfo
- Publication number
- DK562686A DK562686A DK562686A DK562686A DK562686A DK 562686 A DK562686 A DK 562686A DK 562686 A DK562686 A DK 562686A DK 562686 A DK562686 A DK 562686A DK 562686 A DK562686 A DK 562686A
- Authority
- DK
- Denmark
- Prior art keywords
- cardiotonics
- tautomers
- imidazoles
- intermediates
- preparation
- Prior art date
Links
- 239000000496 cardiotonic agent Substances 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/06—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/68—Halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80145885A | 1985-11-25 | 1985-11-25 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK562686D0 DK562686D0 (da) | 1986-11-24 |
| DK562686A true DK562686A (da) | 1987-05-26 |
Family
ID=25181154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK562686A DK562686A (da) | 1985-11-25 | 1986-11-24 | 2,2 -bi-1h-imidazoler, tautomere og farmaceutisk acceptable salte deraf, deres fremstilling og anvendelse som cardiotonika samt mellemprodukter ved fremstillingen |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0229922B1 (da) |
| JP (1) | JPS62135461A (da) |
| KR (1) | KR900000671B1 (da) |
| CN (1) | CN86108027A (da) |
| AT (1) | ATE74912T1 (da) |
| AU (1) | AU585409B2 (da) |
| CA (1) | CA1286301C (da) |
| DE (1) | DE3684900D1 (da) |
| DK (1) | DK562686A (da) |
| ES (1) | ES2036520T3 (da) |
| FI (1) | FI864751A (da) |
| GR (1) | GR3004386T3 (da) |
| HU (1) | HU205087B (da) |
| IL (1) | IL80733A0 (da) |
| NO (1) | NO167801C (da) |
| NZ (1) | NZ218354A (da) |
| PH (1) | PH22526A (da) |
| PT (1) | PT83799B (da) |
| ZA (1) | ZA868809B (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4839375A (en) * | 1987-07-28 | 1989-06-13 | Merrell Dow Pharmaceuticals Inc. | (Aryl or heteroaromatic methyl)-2,2'-bi-1H-imidazoles and their use as anti-hypertensive agents |
| US7322704B2 (en) | 2004-07-30 | 2008-01-29 | Novalux, Inc. | Frequency stabilized vertical extended cavity surface emitting lasers |
| JP4935090B2 (ja) * | 2006-01-31 | 2012-05-23 | ソニー株式会社 | 半導体発光装置 |
| CN101676293B (zh) * | 2008-09-18 | 2012-11-21 | 宁波大学 | 一种联咪唑有机膦化合物及其制备方法 |
| CN102304089A (zh) * | 2011-07-01 | 2012-01-04 | 中国科学院过程工程研究所 | 一种4,4′,5,5′-四硝基-2,2′-联咪唑的合成方法 |
-
1986
- 1986-11-20 CA CA000523502A patent/CA1286301C/en not_active Expired - Lifetime
- 1986-11-20 ZA ZA868809A patent/ZA868809B/xx unknown
- 1986-11-20 PH PH34501A patent/PH22526A/en unknown
- 1986-11-21 FI FI864751A patent/FI864751A/fi not_active Application Discontinuation
- 1986-11-21 EP EP86116131A patent/EP0229922B1/en not_active Expired - Lifetime
- 1986-11-21 NZ NZ218354A patent/NZ218354A/xx unknown
- 1986-11-21 AU AU65565/86A patent/AU585409B2/en not_active Ceased
- 1986-11-21 DE DE8686116131T patent/DE3684900D1/de not_active Expired - Fee Related
- 1986-11-21 AT AT86116131T patent/ATE74912T1/de not_active IP Right Cessation
- 1986-11-21 ES ES198686116131T patent/ES2036520T3/es not_active Expired - Lifetime
- 1986-11-24 PT PT83799A patent/PT83799B/pt not_active IP Right Cessation
- 1986-11-24 DK DK562686A patent/DK562686A/da not_active Application Discontinuation
- 1986-11-24 KR KR1019860009901A patent/KR900000671B1/ko not_active IP Right Cessation
- 1986-11-24 NO NO864695A patent/NO167801C/no unknown
- 1986-11-24 HU HU864855A patent/HU205087B/hu not_active IP Right Cessation
- 1986-11-24 IL IL80733A patent/IL80733A0/xx not_active IP Right Cessation
- 1986-11-25 JP JP61278925A patent/JPS62135461A/ja active Pending
- 1986-11-25 CN CN198686108027A patent/CN86108027A/zh active Pending
-
1992
- 1992-04-16 GR GR920400542T patent/GR3004386T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO167801C (no) | 1991-12-11 |
| NO167801B (no) | 1991-09-02 |
| AU585409B2 (en) | 1989-06-15 |
| GR3004386T3 (da) | 1993-03-31 |
| DK562686D0 (da) | 1986-11-24 |
| PH22526A (en) | 1988-10-17 |
| CA1286301C (en) | 1991-07-16 |
| KR870004977A (ko) | 1987-06-02 |
| EP0229922B1 (en) | 1992-04-15 |
| EP0229922A2 (en) | 1987-07-29 |
| DE3684900D1 (de) | 1992-05-21 |
| FI864751A (fi) | 1987-05-26 |
| FI864751A0 (fi) | 1986-11-21 |
| KR900000671B1 (ko) | 1990-02-02 |
| PT83799B (pt) | 1988-08-17 |
| IL80733A0 (en) | 1987-02-27 |
| NO864695D0 (no) | 1986-11-24 |
| HUT42075A (en) | 1987-06-29 |
| ATE74912T1 (de) | 1992-05-15 |
| JPS62135461A (ja) | 1987-06-18 |
| ES2036520T3 (es) | 1993-06-01 |
| NZ218354A (en) | 1989-09-27 |
| HU205087B (en) | 1992-03-30 |
| CN86108027A (zh) | 1987-10-07 |
| PT83799A (en) | 1986-12-01 |
| ZA868809B (en) | 1987-07-29 |
| EP0229922A3 (en) | 1988-03-30 |
| AU6556586A (en) | 1987-05-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ATS | Application withdrawn |