DK526077A - Derivater af trypsin-kallikrein-inhibitoren fra okseorganer (bpti) med proteansehaemmende virkning og antiphlogistsk virknig en fremgangsmaade til fremstilling deraf og deres anvendelse som laegemidler - Google Patents

Derivater af trypsin-kallikrein-inhibitoren fra okseorganer (bpti) med proteansehaemmende virkning og antiphlogistsk virknig en fremgangsmaade til fremstilling deraf og deres anvendelse som laegemidler

Info

Publication number
DK526077A
DK526077A DK526077A DK526077A DK526077A DK 526077 A DK526077 A DK 526077A DK 526077 A DK526077 A DK 526077A DK 526077 A DK526077 A DK 526077A DK 526077 A DK526077 A DK 526077A
Authority
DK
Denmark
Prior art keywords
organts
callicrain
antiphlogical
bpti
beef
Prior art date
Application number
DK526077A
Other languages
Danish (da)
English (en)
Inventor
E Schnabel
G Reinhardt
H D Schlumberger
E Truscheit
H Tschesche
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of DK526077A publication Critical patent/DK526077A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114—Kunitz type inhibitors
    • C07K14/8117—Bovine/basic pancreatic trypsin inhibitor (BPTI, aprotinin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Peptides Or Proteins (AREA)
DK526077A 1976-11-29 1977-11-28 Derivater af trypsin-kallikrein-inhibitoren fra okseorganer (bpti) med proteansehaemmende virkning og antiphlogistsk virknig en fremgangsmaade til fremstilling deraf og deres anvendelse som laegemidler DK526077A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762654124 DE2654124A1 (de) 1976-11-29 1976-11-29 Derivate des trypsin-kallikrein-inhibitors aus rinderorganen (bpti) mit proteasenhemmwirkung und antiphlogistischer wirkung, ihre herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
DK526077A true DK526077A (da) 1978-05-30

Family

ID=5994225

Family Applications (1)

Application Number Title Priority Date Filing Date
DK526077A DK526077A (da) 1976-11-29 1977-11-28 Derivater af trypsin-kallikrein-inhibitoren fra okseorganer (bpti) med proteansehaemmende virkning og antiphlogistsk virknig en fremgangsmaade til fremstilling deraf og deres anvendelse som laegemidler

Country Status (10)

Country Link
US (1) US4153687A (sv)
JP (1) JPS5368701A (sv)
BE (1) BE861267A (sv)
DE (1) DE2654124A1 (sv)
DK (1) DK526077A (sv)
ES (1) ES464571A1 (sv)
FR (1) FR2373516A1 (sv)
GB (1) GB1557599A (sv)
NL (1) NL7713091A (sv)
SE (1) SE7713436L (sv)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2748294A1 (de) * 1977-10-27 1979-05-03 Bayer Ag Neue derivate des bpti, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2748295A1 (de) * 1977-10-27 1979-05-03 Bayer Ag Neue derivate des bpti
RU2054180C1 (ru) * 1991-08-21 1996-02-10 Жирнов Олег Петрович (н/п) Способ лечения вирусных респираторных инфекций
ES2229236T3 (es) * 1994-01-11 2005-04-16 Dyax Corporation Inhibidores de la plasmina humana derivados de los dominios de kunitz.
ATE275583T1 (de) * 1994-01-11 2004-09-15 Dyax Corp KALLIKREINHEMMENDE ßKUNITZ-DOMÄNEß-PROTEINE UND DERIVATEN DAVON
US6057287A (en) 1994-01-11 2000-05-02 Dyax Corp. Kallikrein-binding "Kunitz domain" proteins and analogues thereof
US20040054082A1 (en) * 2001-12-03 2004-03-18 Bank David H Toughened polymer blends with improved surface properties
ATE477020T1 (de) 2002-06-07 2010-08-15 Dyax Corp Prevention und verringerung von ischemia
US7153829B2 (en) * 2002-06-07 2006-12-26 Dyax Corp. Kallikrein-inhibitor therapies
PT2386310T (pt) 2002-08-28 2019-02-05 Dyax Corp Métodos para preservar órgãos e tecidos
US7235530B2 (en) 2004-09-27 2007-06-26 Dyax Corporation Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
US7276480B1 (en) 2005-12-30 2007-10-02 Dyax Corp. Prevention and reduction of blood loss
JP2009529542A (ja) * 2006-03-10 2009-08-20 ダイアックス コーポレーション エカランチドに関する配合物
AU2010203712A1 (en) * 2009-01-06 2010-07-15 Dyax Corp. Treatment of mucositis with kallikrein inhibitors
JP6037841B2 (ja) * 2010-01-06 2016-12-07 ダイアックス コーポレーション 血漿カリクレイン結合タンパク質
AU2012204202A1 (en) 2011-01-06 2013-07-11 Dyax Corp. Plasma kallikrein binding proteins
CA2838984A1 (en) 2011-06-10 2012-12-13 Isis Pharmaceuticals, Inc. Methods for modulating kallikrein (klkb1) expression
EP2726153B1 (en) 2011-06-29 2018-03-28 Ionis Pharmaceuticals, Inc. Methods for modulating kallikrein (klkb1) expression
EP3715457A3 (en) 2013-08-28 2020-12-16 Ionis Pharmaceuticals, Inc. Modulation of prekallikrein (pkk) expression
US10428158B2 (en) 2014-03-27 2019-10-01 Dyax Corp. Compositions and methods for treatment of diabetic macular edema
US10294477B2 (en) 2014-05-01 2019-05-21 Ionis Pharmaceuticals, Inc. Compositions and methods for modulating PKK expression
CN108602893A (zh) 2015-12-11 2018-09-28 戴埃克斯有限公司 血浆激肽释放酶抑制剂及其治疗遗传性血管性水肿发作的用途

Also Published As

Publication number Publication date
JPS5368701A (en) 1978-06-19
US4153687A (en) 1979-05-08
FR2373516A1 (fr) 1978-07-07
SE7713436L (sv) 1978-05-30
BE861267A (fr) 1978-05-29
FR2373516B1 (sv) 1980-06-13
ES464571A1 (es) 1978-09-01
NL7713091A (nl) 1978-05-31
DE2654124A1 (de) 1978-06-01
GB1557599A (en) 1979-12-12

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