BE861267A - Nouveaux derives de l'inhibiteur de trypsine et de kallicreine d'organes de boeuf a effets antiproteolytique et anti-inflammatoire - Google Patents

Nouveaux derives de l'inhibiteur de trypsine et de kallicreine d'organes de boeuf a effets antiproteolytique et anti-inflammatoire

Info

Publication number
BE861267A
BE861267A BE182978A BE182978A BE861267A BE 861267 A BE861267 A BE 861267A BE 182978 A BE182978 A BE 182978A BE 182978 A BE182978 A BE 182978A BE 861267 A BE861267 A BE 861267A
Authority
BE
Belgium
Prior art keywords
kallicrein
antiproteolytic
beef
trypsin
organs
Prior art date
Application number
BE182978A
Other languages
English (en)
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of BE861267A publication Critical patent/BE861267A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114—Kunitz type inhibitors
    • C07K14/8117—Bovine/basic pancreatic trypsin inhibitor (BPTI, aprotinin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Peptides Or Proteins (AREA)
BE182978A 1976-11-29 1977-11-28 Nouveaux derives de l'inhibiteur de trypsine et de kallicreine d'organes de boeuf a effets antiproteolytique et anti-inflammatoire BE861267A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762654124 DE2654124A1 (de) 1976-11-29 1976-11-29 Derivate des trypsin-kallikrein-inhibitors aus rinderorganen (bpti) mit proteasenhemmwirkung und antiphlogistischer wirkung, ihre herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
BE861267A true BE861267A (fr) 1978-05-29

Family

ID=5994225

Family Applications (1)

Application Number Title Priority Date Filing Date
BE182978A BE861267A (fr) 1976-11-29 1977-11-28 Nouveaux derives de l'inhibiteur de trypsine et de kallicreine d'organes de boeuf a effets antiproteolytique et anti-inflammatoire

Country Status (10)

Country Link
US (1) US4153687A (fr)
JP (1) JPS5368701A (fr)
BE (1) BE861267A (fr)
DE (1) DE2654124A1 (fr)
DK (1) DK526077A (fr)
ES (1) ES464571A1 (fr)
FR (1) FR2373516A1 (fr)
GB (1) GB1557599A (fr)
NL (1) NL7713091A (fr)
SE (1) SE7713436L (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2748294A1 (de) * 1977-10-27 1979-05-03 Bayer Ag Neue derivate des bpti, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2748295A1 (de) * 1977-10-27 1979-05-03 Bayer Ag Neue derivate des bpti
RU2054180C1 (ru) * 1991-08-21 1996-02-10 Жирнов Олег Петрович (н/п) Способ лечения вирусных респираторных инфекций
EP1489097B1 (fr) * 1994-01-11 2011-10-19 Dyax Corporation Inhibiteurs de la plasmine humaine dérivés des domaines de Kunitz
US6057287A (en) 1994-01-11 2000-05-02 Dyax Corp. Kallikrein-binding "Kunitz domain" proteins and analogues thereof
DK0739355T3 (da) * 1994-01-11 2005-01-24 Dyax Corp Kallikrein-inhiberende "Kunitz-domæne"-proteiner og analoger deraf
US20040054082A1 (en) * 2001-12-03 2004-03-18 Bank David H Toughened polymer blends with improved surface properties
DK2311432T3 (en) * 2002-06-07 2015-02-02 Dyax Corp Modified Kunitz domain polypeptides and their use in reducing ischemia or the onset of a systemic inflammatory response associated with a surgical procedure
US7153829B2 (en) * 2002-06-07 2006-12-26 Dyax Corp. Kallikrein-inhibitor therapies
ES2709103T3 (es) * 2002-08-28 2019-04-15 Dyax Corp Métodos para conservar órganos y tejidos
US7235530B2 (en) 2004-09-27 2007-06-26 Dyax Corporation Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
US7276480B1 (en) 2005-12-30 2007-10-02 Dyax Corp. Prevention and reduction of blood loss
JP2009529542A (ja) * 2006-03-10 2009-08-20 ダイアックス コーポレーション エカランチドに関する配合物
CA2744235A1 (fr) * 2009-01-06 2010-07-15 Dyax Corp. Traitement de la mucosite par des inhibiteurs de kallikreine
LT3459564T (lt) * 2010-01-06 2022-03-10 Takeda Pharmaceutical Company Limited Plazmos kalikreiną surišantys baltymai
BR112013017080A8 (pt) 2011-01-06 2023-05-09 Dyax Corp Anticorpo ou fragmento funcional do mesmo que se liga a forma ativa de calicreína do plasma humano, composiçao farmacêutica e método de detecçao de calicreína do plasma em um paciente
EP2717923B1 (fr) 2011-06-10 2017-09-27 Ionis Pharmaceuticals, Inc. Procédés pour moduler l'expression de la kallicréine (klkb1)
US9322021B2 (en) 2011-06-29 2016-04-26 Ionis Pharmaceuticals, Inc. Methods for modulating kallikrein (KLKB1) expression
RU2712559C9 (ru) 2013-08-28 2020-10-08 Ионис Фармасьютикалз, Инк. Модуляция экспрессии прекалликреина (пкк)
EP3122782A4 (fr) 2014-03-27 2017-09-13 Dyax Corp. Compositions et procédés pour le traitement de l'oedème maculaire diabétique
AU2015252917B2 (en) 2014-05-01 2019-09-26 Ionis Pharmaceuticals, Inc. Compositions and methods for modulating PKK expression
KR20180094028A (ko) 2015-12-11 2018-08-22 다이액스 코포레이션 혈장 칼리크레인 저해제 및 유전성 혈관부종 발작을 치료하기 위한 이의 용도

Also Published As

Publication number Publication date
FR2373516A1 (fr) 1978-07-07
JPS5368701A (en) 1978-06-19
GB1557599A (en) 1979-12-12
DK526077A (da) 1978-05-30
SE7713436L (sv) 1978-05-30
ES464571A1 (es) 1978-09-01
FR2373516B1 (fr) 1980-06-13
DE2654124A1 (de) 1978-06-01
US4153687A (en) 1979-05-08
NL7713091A (nl) 1978-05-31

Similar Documents

Publication Publication Date Title
BE861267A (fr) Nouveaux derives de l'inhibiteur de trypsine et de kallicreine d'organes de boeuf a effets antiproteolytique et anti-inflammatoire
MC1220A1 (fr) Nouveaux derives d'imidazolidine
JPS5340780A (en) Production and use of methylol derivative of 2*2*6*6*tetraalkylpyperidine
BE851725A (fr) Nouveaux esters d'acides androstadiene-17-carboxyliques
BE851361A (fr) Nouveaux derives de proline et composes apparentes
BE857519A (fr) Nouveaux derives d'acides azolyl-carboxyliques
FR2348190A1 (fr) Derives quaternaires d'halo-alcanoates gras de dialkylamino-propylamides
IL53352A0 (en) Derivatives of thiazolidinecarboxylic acids and related acids
FR2348182A1 (fr) Nouveaux derives d'acides m-phenyl-phenoxy-propioniques
NZ184975A (en) Derivatives of benzolurea and arthropodicidal compositions
ZA777062B (en) Derivatives of thiazolidinecarboxylic acids and related acids
BE856975A (fr) Nouveaux derives d'acides phenoxyphenoxy-alcanecarboxyliques
SE8001041L (sv) Forsterkare med en matningskrets och ett dertill anslutet forsterkarsteg
JPS5337669A (en) Production and use of 1*44dihydropyridine derivatives
BE850472A (fr) Derives d'imidazothiazole et theiazolopyrimidine antiinflammatoires
BE850089A (fr) Nouveaux derives de l'hydrazine
BE854249A (fr) Nouveaux derives des benzodiazepines
SE7812826L (sv) Derrivat av 6'-epi-forimicin a och b
SE7706269L (sv) Uracilderivat och forfarande for framstellning derav
SE7708111L (sv) Forfarande och anordning for kontinuerlig framstellning av armerade slangar
BE857512A (fr) Nouveaux derives de l'imidazole
BE851463A (fr) Nouveaux derives d'indolizine
SE7711261L (sv) Magnetkerna och forfarande for framstellning av densamma
JPS5318552A (en) Production of tricyclo *6*2*2*03*8* dodecene derivatives
BE853104A (fr) Derives d'acides phenoxy-phenoxy-alcanoiques et composes apparentes