DK503583A - Fremgangsmaade til fremstilling af pyrido(2,3-d)pyrimidin-5-oner - Google Patents

Fremgangsmaade til fremstilling af pyrido(2,3-d)pyrimidin-5-oner Download PDF

Info

Publication number
DK503583A
DK503583A DK503583A DK503583A DK503583A DK 503583 A DK503583 A DK 503583A DK 503583 A DK503583 A DK 503583A DK 503583 A DK503583 A DK 503583A DK 503583 A DK503583 A DK 503583A
Authority
DK
Denmark
Prior art keywords
pyridinyl
carbon atoms
pyrido
pyrimidin
preparation
Prior art date
Application number
DK503583A
Other languages
Danish (da)
English (en)
Other versions
DK503583D0 (da
Inventor
George Yohe Lesher
Baldev Singh
Stanley Chester Laskowski
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of DK503583D0 publication Critical patent/DK503583D0/da
Publication of DK503583A publication Critical patent/DK503583A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
DK503583A 1982-11-05 1983-11-03 Fremgangsmaade til fremstilling af pyrido(2,3-d)pyrimidin-5-oner DK503583A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/439,361 US4432981A (en) 1982-11-05 1982-11-05 2-(Pyridinyl or hydroxyphenyl)-8-substituted pyrido[2,3-d]pyrimidin-5(8H)-ones

Publications (2)

Publication Number Publication Date
DK503583D0 DK503583D0 (da) 1983-11-03
DK503583A true DK503583A (da) 1984-05-06

Family

ID=23744409

Family Applications (1)

Application Number Title Priority Date Filing Date
DK503583A DK503583A (da) 1982-11-05 1983-11-03 Fremgangsmaade til fremstilling af pyrido(2,3-d)pyrimidin-5-oner

Country Status (18)

Country Link
US (1) US4432981A (enExample)
EP (1) EP0108380B1 (enExample)
JP (1) JPS5995287A (enExample)
KR (1) KR890001425B1 (enExample)
AT (1) ATE40891T1 (enExample)
AU (1) AU557800B2 (enExample)
CA (1) CA1234111A (enExample)
DE (1) DE3379223D1 (enExample)
DK (1) DK503583A (enExample)
ES (1) ES526992A0 (enExample)
FI (1) FI76336C (enExample)
GR (1) GR78750B (enExample)
IL (1) IL70060A (enExample)
NO (1) NO162558C (enExample)
NZ (1) NZ206063A (enExample)
PH (1) PH21605A (enExample)
PT (1) PT77610B (enExample)
ZA (1) ZA838178B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4560753A (en) * 1982-11-05 1985-12-24 Sterling Drug Inc. 2-Substituted-pyrido[2,3-d]pyrimidin-5(8H)-ones
DE3438351A1 (de) * 1984-10-19 1986-04-24 Gödecke AG, 1000 Berlin 4-alkoxy-pyrido(2,3-d)pyrimidin-derivate, verfahren zu deren herstellung und deren verwendung
DE3438350A1 (de) * 1984-10-19 1986-04-24 Gödecke AG, 1000 Berlin 4-oxo-pyrido (2,3-d) pyrimidin-derivate, verfahren zu deren herstellung und deren verwendung
US4684653A (en) * 1985-03-08 1987-08-04 The Trustees Of Princeton University Pyrido(2,3-d)pyrimidine derivatives
US4927828A (en) * 1985-03-08 1990-05-22 The Trustees Of Princeton University Diastereoisomeric tetrahydropyrido-(2,3,d) pyrimidine derivatives
ZA861235B (en) * 1985-03-08 1986-10-29 Univ Princeton Pyrido(2,3-d)pyrimidine derivatives
US5026851A (en) * 1985-03-08 1991-06-25 The Trustees Of Princeton University Pyrido[2,3-]pyrimidine derivatives
US4833145A (en) * 1986-06-30 1989-05-23 The Trustees Of Princeton University 4(3H)-oxo-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidine derivatives
US4818819A (en) * 1986-10-20 1989-04-04 The Trustees Of Princeton University Process for the preparation of fused pyridine compounds
US4902796A (en) * 1986-10-20 1990-02-20 The Trustees Of Princeton University 6-alkenyl and ethynyl derivatives of 2-amino-4-hydroxypyrido[2,3-d]pyrimidines
US5028608A (en) * 1989-12-11 1991-07-02 The Trustees Of Princeton University N-(6-Amino-(pyrrolo(2,3-d)pyrimidin-3-ylacyl) )-glutamic acid derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3320257A (en) * 1965-04-12 1967-05-16 Sterling Drug Inc Pyrido[2, 3-d]pyrimidines, pyrido[3, 2-d]pyrimidines, and intermediates and process therefor
US3642797A (en) * 1968-06-10 1972-02-15 Sterling Drug Inc 4h-pyrido(1 2-a)pyrimidin-4-ones
JPS4837279B1 (enExample) * 1970-08-29 1973-11-09
US3673184A (en) * 1970-09-02 1972-06-27 Dainippon Pharmaceutical Co Certain 2-substituted-5,8-dihydro-5-oxopyrido{8 2,3-d{9 pyrimidine-6-carboxylic acid derivatives
BE789496A (enExample) * 1971-10-05 1973-03-29 S M B Anciens Ets J Muelberger
US4018770A (en) * 1975-03-03 1977-04-19 Sterling Drug Inc. N-(2-(pyridinyl)-4-pyrimidinyl)-aminomethylenemalonates and analogs
US3992380A (en) * 1975-03-03 1976-11-16 Sterling Drug Inc. 5,8-Dihydro-5-oxo-2-(4-or 3-pyridinyl)pyrido[2,3-d]pyrimidine-6-carboxylic acids and esters

Also Published As

Publication number Publication date
FI76336C (fi) 1988-10-10
ZA838178B (en) 1984-06-27
DE3379223D1 (de) 1989-03-30
PT77610B (pt) 1986-03-19
CA1234111A (en) 1988-03-15
FI76336B (fi) 1988-06-30
IL70060A0 (en) 1984-01-31
FI833996A0 (fi) 1983-10-31
KR890001425B1 (ko) 1989-05-03
EP0108380A2 (en) 1984-05-16
DK503583D0 (da) 1983-11-03
NO162558B (no) 1989-10-09
US4432981A (en) 1984-02-21
JPS5995287A (ja) 1984-06-01
GR78750B (enExample) 1984-10-02
NO834010L (no) 1984-05-07
EP0108380B1 (en) 1989-02-22
PT77610A (en) 1983-12-01
NO162558C (no) 1990-01-17
EP0108380A3 (en) 1984-09-05
KR840006658A (ko) 1984-12-01
ES8601986A1 (es) 1985-11-16
AU557800B2 (en) 1987-01-08
IL70060A (en) 1987-02-27
PH21605A (en) 1987-12-11
AU2083983A (en) 1984-05-10
ES526992A0 (es) 1985-11-16
ATE40891T1 (de) 1989-03-15
FI833996A7 (fi) 1984-05-06
NZ206063A (en) 1986-10-08

Similar Documents

Publication Publication Date Title
AU557800B2 (en) Pyrido(2,3-d) pyridimin-5-ones
IE811931L (en) Oxiranes.
GR3004250T3 (enExample)
AU547792B2 (en) Pyrimido(5,4-d)pyrimidines
ES8308834A1 (es) Un procedimiento para la preparacion de derivados de etanolamina
ES8703869A1 (es) Procedimiento para preparar compuestos de 5-alaquil-1-fenil-2-piperazinoalquilpirazolin-3-ona.
DK0383686T3 (da) Carboxyalkylethere af 2-amino-7-hydroxytetralin samt fremgangsmåde til fremstilling deraf
JPS5535067A (en) Novel urea derivative and its preparation
JPS5610175A (en) Preparation of imidazole derivative
PH17716A (en) Antithrombotic sulfimino and sulfoximino indolinones-2
ES475596A1 (es) Procedimiento para la preparacion de derivados de fenoxial- canolaminas
DE3164005D1 (en) Use of alpha-azolylglycoles as plant growth regulators
ATE21387T1 (de) Hydrochinonabkoemmlinge, sowie verfahren zu deren herstellung.
GB1507414A (en) Hydantoin derivatives
ES8207543A1 (es) Un procedimiento para la preparacion de nuevos derivados heterotriciclicos jaula.
JPS5610149A (en) Preparation of nitrotoluene derivative
JPS57102892A (en) Thiopyranopyridobenzoxazol-7-one derivative
ES8609300A1 (es) Un procedimiento para la preparacion de nuevas amonicas derivadas de 1,2,3,4,4a,10a-hexahidrodibenzo(b,e)(1,4)-dioxin 4,ol.
JPS56120639A (en) Biphenyl derivative
JPS5655371A (en) Quinoline derivative
ES8302712A1 (es) Un nuevo procedimiento de preparacion de imidazobenzodiazepinas.
JPS5793972A (en) Preparation of piperazine derivative

Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment