DK503583D0 - Fremgangsmade til fremstilling af pyrido (2,3-d) pyrimidin-5-oner - Google Patents

Fremgangsmade til fremstilling af pyrido (2,3-d) pyrimidin-5-oner

Info

Publication number
DK503583D0
DK503583D0 DK5035/83A DK503583A DK503583D0 DK 503583 D0 DK503583 D0 DK 503583D0 DK 5035/83 A DK5035/83 A DK 5035/83A DK 503583 A DK503583 A DK 503583A DK 503583 D0 DK503583 D0 DK 503583D0
Authority
DK
Denmark
Prior art keywords
pyridinyl
carbon atoms
pyrido
pyrimidin
preparation
Prior art date
Application number
DK5035/83A
Other languages
English (en)
Other versions
DK503583A (da
Inventor
George Yohe Lesher
Baldev Singh
Stanley Chester Laskowski
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of DK503583D0 publication Critical patent/DK503583D0/da
Publication of DK503583A publication Critical patent/DK503583A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/041,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/061,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/14Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
DK503583A 1982-11-05 1983-11-03 Fremgangsmaade til fremstilling af pyrido(2,3-d)pyrimidin-5-oner DK503583A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/439,361 US4432981A (en) 1982-11-05 1982-11-05 2-(Pyridinyl or hydroxyphenyl)-8-substituted pyrido[2,3-d]pyrimidin-5(8H)-ones

Publications (2)

Publication Number Publication Date
DK503583D0 true DK503583D0 (da) 1983-11-03
DK503583A DK503583A (da) 1984-05-06

Family

ID=23744409

Family Applications (1)

Application Number Title Priority Date Filing Date
DK503583A DK503583A (da) 1982-11-05 1983-11-03 Fremgangsmaade til fremstilling af pyrido(2,3-d)pyrimidin-5-oner

Country Status (18)

Country Link
US (1) US4432981A (da)
EP (1) EP0108380B1 (da)
JP (1) JPS5995287A (da)
KR (1) KR890001425B1 (da)
AT (1) ATE40891T1 (da)
AU (1) AU557800B2 (da)
CA (1) CA1234111A (da)
DE (1) DE3379223D1 (da)
DK (1) DK503583A (da)
ES (1) ES8601986A1 (da)
FI (1) FI76336C (da)
GR (1) GR78750B (da)
IL (1) IL70060A (da)
NO (1) NO162558C (da)
NZ (1) NZ206063A (da)
PH (1) PH21605A (da)
PT (1) PT77610B (da)
ZA (1) ZA838178B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4560753A (en) * 1982-11-05 1985-12-24 Sterling Drug Inc. 2-Substituted-pyrido[2,3-d]pyrimidin-5(8H)-ones
DE3438350A1 (de) * 1984-10-19 1986-04-24 Gödecke AG, 1000 Berlin 4-oxo-pyrido (2,3-d) pyrimidin-derivate, verfahren zu deren herstellung und deren verwendung
DE3438351A1 (de) * 1984-10-19 1986-04-24 Gödecke AG, 1000 Berlin 4-alkoxy-pyrido(2,3-d)pyrimidin-derivate, verfahren zu deren herstellung und deren verwendung
US5026851A (en) * 1985-03-08 1991-06-25 The Trustees Of Princeton University Pyrido[2,3-]pyrimidine derivatives
US4927828A (en) * 1985-03-08 1990-05-22 The Trustees Of Princeton University Diastereoisomeric tetrahydropyrido-(2,3,d) pyrimidine derivatives
US4684653A (en) * 1985-03-08 1987-08-04 The Trustees Of Princeton University Pyrido(2,3-d)pyrimidine derivatives
ZA861235B (en) * 1985-03-08 1986-10-29 Univ Princeton Pyrido(2,3-d)pyrimidine derivatives
US4833145A (en) * 1986-06-30 1989-05-23 The Trustees Of Princeton University 4(3H)-oxo-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidine derivatives
US4902796A (en) * 1986-10-20 1990-02-20 The Trustees Of Princeton University 6-alkenyl and ethynyl derivatives of 2-amino-4-hydroxypyrido[2,3-d]pyrimidines
US4818819A (en) * 1986-10-20 1989-04-04 The Trustees Of Princeton University Process for the preparation of fused pyridine compounds
US5028608A (en) * 1989-12-11 1991-07-02 The Trustees Of Princeton University N-(6-Amino-(pyrrolo(2,3-d)pyrimidin-3-ylacyl) )-glutamic acid derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3320257A (en) * 1965-04-12 1967-05-16 Sterling Drug Inc Pyrido[2, 3-d]pyrimidines, pyrido[3, 2-d]pyrimidines, and intermediates and process therefor
US3642797A (en) * 1968-06-10 1972-02-15 Sterling Drug Inc 4h-pyrido(1 2-a)pyrimidin-4-ones
JPS4837279B1 (da) * 1970-08-29 1973-11-09
US3673184A (en) * 1970-09-02 1972-06-27 Dainippon Pharmaceutical Co Certain 2-substituted-5,8-dihydro-5-oxopyrido{8 2,3-d{9 pyrimidine-6-carboxylic acid derivatives
BE789496A (da) * 1971-10-05 1973-03-29 S M B Anciens Ets J Muelberger
US3992380A (en) * 1975-03-03 1976-11-16 Sterling Drug Inc. 5,8-Dihydro-5-oxo-2-(4-or 3-pyridinyl)pyrido[2,3-d]pyrimidine-6-carboxylic acids and esters
US4018770A (en) * 1975-03-03 1977-04-19 Sterling Drug Inc. N-(2-(pyridinyl)-4-pyrimidinyl)-aminomethylenemalonates and analogs

Also Published As

Publication number Publication date
FI833996A (fi) 1984-05-06
PT77610B (pt) 1986-03-19
KR840006658A (ko) 1984-12-01
NZ206063A (en) 1986-10-08
IL70060A0 (en) 1984-01-31
PT77610A (en) 1983-12-01
NO162558C (no) 1990-01-17
PH21605A (en) 1987-12-11
KR890001425B1 (ko) 1989-05-03
DE3379223D1 (de) 1989-03-30
ATE40891T1 (de) 1989-03-15
NO834010L (no) 1984-05-07
FI76336B (fi) 1988-06-30
ES526992A0 (es) 1985-11-16
EP0108380A2 (en) 1984-05-16
NO162558B (no) 1989-10-09
AU2083983A (en) 1984-05-10
CA1234111A (en) 1988-03-15
DK503583A (da) 1984-05-06
EP0108380A3 (en) 1984-09-05
ZA838178B (en) 1984-06-27
AU557800B2 (en) 1987-01-08
IL70060A (en) 1987-02-27
GR78750B (da) 1984-10-02
ES8601986A1 (es) 1985-11-16
US4432981A (en) 1984-02-21
EP0108380B1 (en) 1989-02-22
FI833996A0 (fi) 1983-10-31
FI76336C (fi) 1988-10-10
JPS5995287A (ja) 1984-06-01

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Legal Events

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AHS Application shelved for other reasons than non-payment