DK497284A - Phenoxypropanolaminer - Google Patents
Phenoxypropanolaminer Download PDFInfo
- Publication number
- DK497284A DK497284A DK497284A DK497284A DK497284A DK 497284 A DK497284 A DK 497284A DK 497284 A DK497284 A DK 497284A DK 497284 A DK497284 A DK 497284A DK 497284 A DK497284 A DK 497284A
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- optionally
- group
- see diagramm
- mono
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH568483 | 1983-10-19 | ||
| CH428884 | 1984-09-07 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK497284D0 DK497284D0 (da) | 1984-10-17 |
| DK497284A true DK497284A (da) | 1985-04-20 |
Family
ID=25695136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK497284A DK497284A (da) | 1983-10-19 | 1984-10-17 | Phenoxypropanolaminer |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5064863A (no) |
| EP (1) | EP0140243B1 (no) |
| AT (1) | ATE38510T1 (no) |
| AU (1) | AU575590B2 (no) |
| CA (1) | CA1262729A (no) |
| DE (1) | DE3475066D1 (no) |
| DK (1) | DK497284A (no) |
| DO (1) | DOP1984004282A (no) |
| FI (1) | FI844082L (no) |
| HU (1) | HU200992B (no) |
| IL (1) | IL73239A (no) |
| MC (1) | MC1625A1 (no) |
| NO (1) | NO159791C (no) |
| NZ (1) | NZ209866A (no) |
| PH (1) | PH21479A (no) |
| PT (1) | PT79371B (no) |
| ZW (1) | ZW16684A1 (no) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8418472D0 (en) * | 1984-07-19 | 1984-08-22 | Beecham Group Plc | Compounds |
| DE3866984D1 (en) * | 1987-07-21 | 1992-01-30 | Hoffmann La Roche | Phenoxypropanolamine. |
| GB8801306D0 (en) * | 1988-01-21 | 1988-02-17 | Ici Plc | Chemical compounds |
| GB8905336D0 (en) * | 1989-03-08 | 1989-04-19 | Ici Plc | Chemical compounds |
| US5177219A (en) * | 1992-03-06 | 1993-01-05 | American Home Products Corporation | N-phenyl-N'-thienylmethyl-bis-diamino-5-methylene-1,3-dioxane-4,6-dione compounds |
| US5321036A (en) * | 1993-02-10 | 1994-06-14 | Bristol-Myers Squibb Company | Thiazole and oxazole-based β3 adrenergic receptor agonists |
| CA2145257A1 (en) * | 1994-03-23 | 1995-09-24 | Takashi Fujita | Thiazolidine and oxazolidine derivatives, their preparation and their medical use |
| US5488064A (en) * | 1994-05-02 | 1996-01-30 | Bristol-Myers Squibb Company | Benzo 1,3 dioxole derivatives |
| CA2196193A1 (en) * | 1994-07-29 | 1996-02-15 | Lee James Beeley | Aryloxy and arylthiopropanolamine derivatives useful as beta 3-adrenoreceptor agonists and antagonists of the beta 1 and beta 2-adrenoreceptors and pharmaceutical composition thereof |
| US5726165A (en) * | 1994-07-29 | 1998-03-10 | Smithkline Beecham P.L.C. | Derivatives of 4-(2-aminoethyl)phenoxymethyl-phosphonic and -phosphinic acid and pharmaceutical and veterinary uses therefor |
| US5491134A (en) * | 1994-09-16 | 1996-02-13 | Bristol-Myers Squibb Company | Sulfonic, phosphonic or phosphiniic acid β3 agonist derivatives |
| US6075040A (en) * | 1996-09-05 | 2000-06-13 | Eli Lilly And Company | Selective β3 adrenergic agonists |
| ZA967892B (en) * | 1995-09-21 | 1998-03-18 | Lilly Co Eli | Selective β3 adrenergic agonists. |
| EP0827746B1 (en) | 1996-09-05 | 2002-04-03 | Eli Lilly And Company | Carbazole analogues as selective beta3 adrenergic agonists |
| GB9703492D0 (en) * | 1997-02-20 | 1997-04-09 | Smithkline Beecham Plc | Novel compounds |
| UY24949A1 (es) * | 1997-04-08 | 2001-04-30 | Smithkline Beecham Corp | Compuestos calcilíticos |
| CO5011072A1 (es) | 1997-12-05 | 2001-02-28 | Lilly Co Eli | Etanolaminas pirazinil substituidas como agfonistas de los receptores |
| WO2001035947A2 (en) * | 1999-11-15 | 2001-05-25 | Eli Lilly And Company | Treating wasting syndromes with aryloxy propanolamines |
| US6239313B1 (en) * | 2000-02-16 | 2001-05-29 | Council Of Scientific And Industrial Research | Process for the solid state synthesis of enantiopure B-aminoalcohols from racemic epoxides |
| TWI249515B (en) * | 2001-11-13 | 2006-02-21 | Theravance Inc | Aryl aniline beta2 adrenergic receptor agonists |
| US20030229058A1 (en) | 2001-11-13 | 2003-12-11 | Moran Edmund J. | Aryl aniline beta2 adrenergic receptor agonists |
| WO2003042160A1 (en) | 2001-11-13 | 2003-05-22 | Theravance, Inc. | Aryl aniline beta-2 adrenergic receptor agonists |
| EP1778638A1 (en) * | 2004-07-21 | 2007-05-02 | Theravance, Inc. | Diaryl ether beta2 adrenergic receptor agonists |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL301580A (no) * | 1962-12-11 | |||
| US4127675A (en) * | 1968-11-12 | 1978-11-28 | Yamanouchi Pharmaceutical Co., Ltd. | 4-(Alkylamino-2-hydroxypropoxy)-indenes and method of use |
| CA957364A (en) * | 1968-11-18 | 1974-11-05 | Pfizer Corporation | Preparation of polar-substituted phenyl propanolamines |
| CA956632A (en) * | 1969-05-16 | 1974-10-22 | Yoshitomi Pharmaceutical Industries | Phenoxy-aminopropanol derivatives |
| FR2119844B1 (no) * | 1970-12-28 | 1974-03-22 | Laroche Navarro Labo | |
| SE388849B (sv) * | 1974-02-14 | 1976-10-18 | Haessle Ab | Forfarande for framstellning av nya aminer med beta-receptorstimulerande verkan |
| SE402764B (sv) * | 1975-06-04 | 1978-07-17 | Haessle Ab | Forfarande for framstellning av nya hjertaktiva foreningar |
| US4165384A (en) * | 1974-11-01 | 1979-08-21 | Aktiebolaget Hassle | Amide substituted phenoxy propanol amines |
| DE2503222A1 (de) * | 1975-01-27 | 1976-07-29 | Boehringer Sohn Ingelheim | Verfahren zur herstellung von 1-aryl- oxy-3-n-substituierten aminopropanderivaten |
| FR2330383A1 (fr) * | 1975-11-06 | 1977-06-03 | Synthelabo | Nouveaux ethers de phenols substitues, leurs sels, leur preparation et les medicaments qui les renferment |
| DE2645710C2 (de) * | 1976-10-09 | 1985-06-27 | Merck Patent Gmbh, 6100 Darmstadt | Phenoxy-amino-propanole, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitung |
| US4263325A (en) * | 1977-10-05 | 1981-04-21 | Aktiebolaget Hassle | β-Receptor blocking compounds and treatment of cardiovascular disorders therewith |
| CA1142954A (en) * | 1978-07-03 | 1983-03-15 | Jack Mills | Phenethanolamines, compositions containing the same, and method for effecting weight control |
| DE3012012A1 (de) * | 1980-03-28 | 1981-10-08 | Beiersdorf Ag, 2000 Hamburg | Substituierte 3-aryl-2-cycloalken-1-one und verfahren zu ihrer herstellung |
| ZW9881A1 (en) * | 1980-06-02 | 1981-12-23 | Hoffmann La Roche | Substituted phenoxyaminopropanol derivatives |
| DE3125870C2 (de) * | 1980-07-09 | 1994-09-15 | William John Louis | 3-Aminopropoxyphenyl Derivate, ihre Herstellung und sie enthaltende Arzneimittel |
| DE3169094D1 (en) * | 1980-11-20 | 1985-03-28 | Beecham Group Plc | Secondary amines |
| IL65541A0 (en) * | 1981-05-06 | 1982-07-30 | Haessle Ab | Alkylamino-2-propanols,process for their preparation and pharmaceutical preparations containing same |
| DE3368258D1 (en) * | 1982-07-16 | 1987-01-22 | Beecham Group Plc | 2-aminoethyl ether derivatives, processes for their preparation and pharmaceutical compositions containing them |
| ZA835687B (en) * | 1982-08-10 | 1984-03-28 | Hoffmann La Roche | Novel phenethanolamines |
| CA1258454A (en) * | 1982-08-10 | 1989-08-15 | Leo Alig | Phenethanolamines |
| GB8418472D0 (en) * | 1984-07-19 | 1984-08-22 | Beecham Group Plc | Compounds |
-
1984
- 1984-09-27 CA CA000464126A patent/CA1262729A/en not_active Expired
- 1984-09-28 AU AU33706/84A patent/AU575590B2/en not_active Ceased
- 1984-10-11 DE DE8484112213T patent/DE3475066D1/de not_active Expired
- 1984-10-11 AT AT84112213T patent/ATE38510T1/de not_active IP Right Cessation
- 1984-10-11 EP EP84112213A patent/EP0140243B1/de not_active Expired
- 1984-10-12 ZW ZW166/84A patent/ZW16684A1/xx unknown
- 1984-10-12 NZ NZ209866A patent/NZ209866A/xx unknown
- 1984-10-15 IL IL8473239A patent/IL73239A/xx unknown
- 1984-10-15 HU HU843846A patent/HU200992B/hu not_active IP Right Cessation
- 1984-10-16 MC MC841733A patent/MC1625A1/xx unknown
- 1984-10-17 DK DK497284A patent/DK497284A/da not_active Application Discontinuation
- 1984-10-17 FI FI844082A patent/FI844082L/fi not_active Application Discontinuation
- 1984-10-17 PH PH31350A patent/PH21479A/en unknown
- 1984-10-18 DO DO1984004282A patent/DOP1984004282A/es unknown
- 1984-10-18 PT PT79371A patent/PT79371B/pt unknown
- 1984-10-18 NO NO84844176A patent/NO159791C/no unknown
-
1987
- 1987-12-10 US US07/130,929 patent/US5064863A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| NO844176L (no) | 1985-04-22 |
| HUT37743A (en) | 1986-02-28 |
| HU200992B (en) | 1990-09-28 |
| PT79371A (en) | 1984-11-01 |
| DK497284D0 (da) | 1984-10-17 |
| IL73239A0 (en) | 1985-01-31 |
| EP0140243A3 (en) | 1986-07-02 |
| EP0140243B1 (de) | 1988-11-09 |
| NO159791C (no) | 1989-02-08 |
| DE3475066D1 (de) | 1988-12-15 |
| AU575590B2 (en) | 1988-08-04 |
| MC1625A1 (fr) | 1985-09-26 |
| NZ209866A (en) | 1988-07-28 |
| PT79371B (en) | 1986-11-20 |
| FI844082A0 (fi) | 1984-10-17 |
| DOP1984004282A (es) | 1990-03-22 |
| IL73239A (en) | 1989-05-15 |
| NO159791B (no) | 1988-10-31 |
| CA1262729A (en) | 1989-11-07 |
| AU3370684A (en) | 1985-04-26 |
| FI844082L (fi) | 1985-04-20 |
| EP0140243A2 (de) | 1985-05-08 |
| US5064863A (en) | 1991-11-12 |
| ATE38510T1 (de) | 1988-11-15 |
| ZW16684A1 (en) | 1985-05-15 |
| PH21479A (en) | 1987-10-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment | ||
| AHB | Application shelved due to non-payment | ||
| AHS | Application shelved for other reasons than non-payment |