DK494989A - Enzymreaktor med dynamisk kontinuerlig stroemning - Google Patents

Enzymreaktor med dynamisk kontinuerlig stroemning Download PDF

Info

Publication number
DK494989A
DK494989A DK494989A DK494989A DK494989A DK 494989 A DK494989 A DK 494989A DK 494989 A DK494989 A DK 494989A DK 494989 A DK494989 A DK 494989A DK 494989 A DK494989 A DK 494989A
Authority
DK
Denmark
Prior art keywords
enzym
reactor
continuous flow
dynamic continuous
dynamic
Prior art date
Application number
DK494989A
Other languages
English (en)
Other versions
DK494989D0 (da
Inventor
Yale Nemerson
Vincent Turitto
Original Assignee
Sinai School Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sinai School Medicine filed Critical Sinai School Medicine
Publication of DK494989D0 publication Critical patent/DK494989D0/da
Publication of DK494989A publication Critical patent/DK494989A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00Bioreactors or fermenters specially adapted for specific uses
    • C12M21/18Apparatus specially designed for the use of free, immobilized or carrier-bound enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • C12M23/06Tubular
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/948Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433Serine endopeptidases (3.4.21)
    • G01N2333/96441Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96444Factor X (3.4.21.6)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/948Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433Serine endopeptidases (3.4.21)
    • G01N2333/96441Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96447Factor VII (3.4.21.21)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/948Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433Serine endopeptidases (3.4.21)
    • G01N2333/96441Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96463Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/948Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/974Thrombin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2405/00Assays, e.g. immunoassays or enzyme assays, involving lipids
    • G01N2405/04Phospholipids, i.e. phosphoglycerides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Sustainable Development (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Clinical Laboratory Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK494989A 1988-02-08 1989-10-06 Enzymreaktor med dynamisk kontinuerlig stroemning DK494989A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/154,083 US4865984A (en) 1988-02-08 1988-02-08 Dynamic continuous flow enzyme reactor
PCT/US1989/000397 WO1989007133A2 (en) 1988-02-08 1989-02-01 Dynamic continuous flow enzyme reactor

Publications (2)

Publication Number Publication Date
DK494989D0 DK494989D0 (da) 1989-10-06
DK494989A true DK494989A (da) 1989-12-07

Family

ID=22549933

Family Applications (1)

Application Number Title Priority Date Filing Date
DK494989A DK494989A (da) 1988-02-08 1989-10-06 Enzymreaktor med dynamisk kontinuerlig stroemning

Country Status (8)

Country Link
US (1) US4865984A (da)
EP (1) EP0353291B1 (da)
JP (1) JP2756606B2 (da)
AU (1) AU607661B2 (da)
CA (1) CA1282361C (da)
DK (1) DK494989A (da)
FI (1) FI90254C (da)
WO (1) WO1989007133A2 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5045479A (en) * 1988-07-05 1991-09-03 The Johns Hopkins University Continuous flow competitive assay with reference system
GB9022938D0 (en) * 1990-10-22 1990-12-05 Biocompatibles Ltd Non-thrombogenic surfaces
US5314695A (en) 1990-11-13 1994-05-24 Corvas International, Inc. Tissue factor based prothrombin time reagent
US6203816B1 (en) * 1990-11-13 2001-03-20 Corvas International, Inc. Tissue factor based prothrombin time reagent
DE69224622T2 (de) * 1991-10-04 1998-11-05 Dade Behring Inc Herstellung von prothrombinzeit-reagenzien aus rekombinantem menschlichem gewebefaktor und sythetischen phospholipiden
US6114135A (en) * 1991-11-08 2000-09-05 Goldstein; Sheldon Multiple coagulation test system and method of using a multiple coagulation test system
US5366869A (en) * 1991-11-08 1994-11-22 Sheldon Goldstein Multiple coagulation test device and method
AU696924B2 (en) * 1994-04-28 1998-09-24 Dade Behring Inc. Calibrator for prothrombin time (PT) assays
US5731212A (en) * 1994-12-20 1998-03-24 International Technidyne Corporation Test apparatus and method for testing cuvette accommodated samples
US20030232075A1 (en) * 2002-05-06 2003-12-18 University Of Minnesota, A Minnesota Corporation Compositions for producing factor Xa
WO2006088741A2 (en) * 2005-02-16 2006-08-24 The Board Of Trustees Of The University Of Illinois Procoagulants based on metal-chelating lipids
EP1869082B1 (en) * 2005-03-04 2011-04-13 The Board Of Trustees Of The University Of Illinois Coagulation and fibrinolytic cascades modulator
WO2009046194A2 (en) * 2007-10-05 2009-04-09 The Board Of Trustees Of The University Of Illinois Fibrin sealant
WO2009061697A1 (en) 2007-11-09 2009-05-14 The Board Of Trustees Of The University Of Illinois Anticoagulant antagonist and hemophilia procoagulant
US8372343B2 (en) 2007-12-07 2013-02-12 Sheldon Goldstein Multiple coagulation test cartridge and method of using same
AU2008343162B2 (en) 2007-12-20 2012-02-23 Alcon Inc. Method for making contact lenses
EP3291208B1 (en) 2016-08-31 2020-09-30 Ricoh Company, Ltd. Hydrogel structure, blood vessel, internal organ model, practice tool for medical procedure, and method of manufacturing the hydrogel structure
US10429377B1 (en) 2019-03-15 2019-10-01 Coagulation Sciences Llc Coagulation test device, system, and method of use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3785772A (en) * 1971-12-08 1974-01-15 Blowitz M Blood analyzer
ATE16456T1 (de) * 1979-06-11 1985-11-15 Gambro Lundia Ab Vorrichtung zum entfernen von substanzen aus einer fluessigkeit.
US4452682A (en) * 1980-10-24 1984-06-05 Hitachi, Ltd. Apparatus for measuring clinical emergency check items of blood
DE3311287A1 (de) * 1983-03-28 1984-10-04 Behringwerke Ag, 3550 Marburg Verfahren zur fotometrischen bestimmung der aktivierten partiellen thromboplastinzeit und reagenz dazu
US4604182A (en) * 1983-08-15 1986-08-05 E. I. Du Pont De Nemours And Company Perfluorosulfonic acid polymer-coated indicator electrodes

Also Published As

Publication number Publication date
EP0353291B1 (en) 1993-01-27
FI894472A0 (fi) 1989-09-21
CA1282361C (en) 1991-04-02
AU3060489A (en) 1989-08-25
FI894472A (fi) 1989-09-21
JP2756606B2 (ja) 1998-05-25
DK494989D0 (da) 1989-10-06
FI90254B (fi) 1993-09-30
WO1989007133A3 (en) 1989-09-08
EP0353291A1 (en) 1990-02-07
FI90254C (fi) 1994-01-10
US4865984A (en) 1989-09-12
AU607661B2 (en) 1991-03-07
JPH02503057A (ja) 1990-09-27
WO1989007133A2 (en) 1989-08-10

Similar Documents

Publication Publication Date Title
DK494989D0 (da) Enzymreaktor med dynamisk kontinuerlig stroemning
DK470787D0 (da) Enzymer med aendret aktivitet
DE3674845D1 (de) Traegergeraet und spanngeraet das traegergeraet umfassend.
FI905579A0 (fi) Modem med flera arbetssaett.
DK68184D0 (da) Begraenser med dynamisk hysterese
BR8504907A (pt) Helio propulsora
DK62586A (da) Fibrinolytisk enzym
IT1153916B (it) Pastiglie d'assorbimento di neutroni aventi microstruttura modificata
DK165687A (da) Modificeret fibrinolytisk enzym
DK508084D0 (da) Modificerede glucosaminoglucaner med antithrombotisk aktivitet
DK495586A (da) Piperazinoisothiazoloner med psykotrop aktivitet
DK5588A (da) Trykformindsker med regulerbart udloebstryk
DK165887A (da) Modificeret fibrinolytisk enzym
IT8421933A0 (it) Sostanze ad attivita'ipolipemizzante.
IT1197688B (it) Attivita' antiflogistica,analgesica,antipiretica ed antiaggregante piastrinica di 1-metil-5-metilbenzoilpirrol-2-acetamido acetanilidi
DK492386D0 (da) Bicycliske imider med psykotrop aktivitet
PT86124A (pt) Granada com armacao dinamica
NO176574C (no) Dynamisk kontinuerlig strömmende enzymreaktor
DK328089D0 (da) Enzym
DK205488D0 (da) Enzym
DK124390D0 (da) Prostaglandinderivater med antitrombotisk virkning
DK402985D0 (da) Reaktor med fluidum-vaeg
FI853766A0 (fi) Cb-oeverdrag med hoeg fastmaterialhalt.
SE8803166D0 (sv) Vikpall med dammsperr
KR860004717U (ko) 각도기와 자

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment