FI894472A - Dynaaminen jatkuvavirtauksinen entsyymireaktori - Google Patents

Dynaaminen jatkuvavirtauksinen entsyymireaktori Download PDF

Info

Publication number
FI894472A
FI894472A FI894472A FI894472A FI894472A FI 894472 A FI894472 A FI 894472A FI 894472 A FI894472 A FI 894472A FI 894472 A FI894472 A FI 894472A FI 894472 A FI894472 A FI 894472A
Authority
FI
Finland
Prior art keywords
continuous flow
flow dynamic
enzyme reactor
dynamic enzyme
reactor
Prior art date
Application number
FI894472A
Other languages
English (en)
Swedish (sv)
Other versions
FI90254B (fi
FI90254C (fi
FI894472A0 (fi
Inventor
Yale Nemerson
Vincent Turitto
Original Assignee
Sinai School Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sinai School Medicine filed Critical Sinai School Medicine
Publication of FI894472A0 publication Critical patent/FI894472A0/fi
Publication of FI894472A publication Critical patent/FI894472A/fi
Publication of FI90254B publication Critical patent/FI90254B/fi
Application granted granted Critical
Publication of FI90254C publication Critical patent/FI90254C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/18—Apparatus specially designed for the use of free, immobilized or carrier-bound enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/06—Tubular
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)
    • G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96444—Factor X (3.4.21.6)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)
    • G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96447—Factor VII (3.4.21.21)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)
    • G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96463—Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/974—Thrombin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
    • G01N2405/04—Phospholipids, i.e. phosphoglycerides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Sustainable Development (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Clinical Laboratory Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
FI894472A 1988-02-08 1989-09-21 Dynaaminen jatkuvavirtauksinen entsyymireaktori FI90254C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US07/154,083 US4865984A (en) 1988-02-08 1988-02-08 Dynamic continuous flow enzyme reactor
US15408388 1988-02-08
PCT/US1989/000397 WO1989007133A2 (en) 1988-02-08 1989-02-01 Dynamic continuous flow enzyme reactor
US8900397 1989-02-01

Publications (4)

Publication Number Publication Date
FI894472A0 FI894472A0 (fi) 1989-09-21
FI894472A true FI894472A (fi) 1989-09-21
FI90254B FI90254B (fi) 1993-09-30
FI90254C FI90254C (fi) 1994-01-10

Family

ID=22549933

Family Applications (1)

Application Number Title Priority Date Filing Date
FI894472A FI90254C (fi) 1988-02-08 1989-09-21 Dynaaminen jatkuvavirtauksinen entsyymireaktori

Country Status (8)

Country Link
US (1) US4865984A (fi)
EP (1) EP0353291B1 (fi)
JP (1) JP2756606B2 (fi)
AU (1) AU607661B2 (fi)
CA (1) CA1282361C (fi)
DK (1) DK494989A (fi)
FI (1) FI90254C (fi)
WO (1) WO1989007133A2 (fi)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5045479A (en) * 1988-07-05 1991-09-03 The Johns Hopkins University Continuous flow competitive assay with reference system
GB9022938D0 (en) * 1990-10-22 1990-12-05 Biocompatibles Ltd Non-thrombogenic surfaces
US5314695A (en) † 1990-11-13 1994-05-24 Corvas International, Inc. Tissue factor based prothrombin time reagent
US6203816B1 (en) * 1990-11-13 2001-03-20 Corvas International, Inc. Tissue factor based prothrombin time reagent
AU663343B2 (en) * 1991-10-04 1995-10-05 Dade Behring Inc. Preparation of prothrombin time reagents from recombinant human tissue factor and purified natural and synthetic phospholipids
US5366869A (en) * 1991-11-08 1994-11-22 Sheldon Goldstein Multiple coagulation test device and method
US6114135A (en) * 1991-11-08 2000-09-05 Goldstein; Sheldon Multiple coagulation test system and method of using a multiple coagulation test system
AU696924B2 (en) * 1994-04-28 1998-09-24 Dade Behring Inc. Calibrator for prothrombin time (PT) assays
US5731212A (en) * 1994-12-20 1998-03-24 International Technidyne Corporation Test apparatus and method for testing cuvette accommodated samples
US20030232075A1 (en) * 2002-05-06 2003-12-18 University Of Minnesota, A Minnesota Corporation Compositions for producing factor Xa
CN101151533A (zh) * 2005-02-16 2008-03-26 伊利诺斯大学理事会 基于金属螯合脂质的促凝血剂
ATE505488T1 (de) * 2005-03-04 2011-04-15 Univ Illinois Modulator von coagulationskaskaden und fibrinolytischen kaskaden
WO2009046194A2 (en) * 2007-10-05 2009-04-09 The Board Of Trustees Of The University Of Illinois Fibrin sealant
WO2009061697A1 (en) * 2007-11-09 2009-05-14 The Board Of Trustees Of The University Of Illinois Anticoagulant antagonist and hemophilia procoagulant
US8372343B2 (en) * 2007-12-07 2013-02-12 Sheldon Goldstein Multiple coagulation test cartridge and method of using same
BRPI0821158A2 (pt) 2007-12-20 2015-06-16 Novartis Ag Método para fazer lentes de contato
EP3291208B1 (en) 2016-08-31 2020-09-30 Ricoh Company, Ltd. Hydrogel structure, blood vessel, internal organ model, practice tool for medical procedure, and method of manufacturing the hydrogel structure
US10429377B1 (en) 2019-03-15 2019-10-01 Coagulation Sciences Llc Coagulation test device, system, and method of use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3785772A (en) * 1971-12-08 1974-01-15 Blowitz M Blood analyzer
DE2967545D1 (en) * 1979-06-11 1985-12-19 Gambro Lundia Ab A device for removal of substances from a liquid
US4452682A (en) * 1980-10-24 1984-06-05 Hitachi, Ltd. Apparatus for measuring clinical emergency check items of blood
DE3311287A1 (de) * 1983-03-28 1984-10-04 Behringwerke Ag, 3550 Marburg Verfahren zur fotometrischen bestimmung der aktivierten partiellen thromboplastinzeit und reagenz dazu
US4604182A (en) * 1983-08-15 1986-08-05 E. I. Du Pont De Nemours And Company Perfluorosulfonic acid polymer-coated indicator electrodes

Also Published As

Publication number Publication date
AU607661B2 (en) 1991-03-07
WO1989007133A2 (en) 1989-08-10
AU3060489A (en) 1989-08-25
FI90254B (fi) 1993-09-30
US4865984A (en) 1989-09-12
DK494989D0 (da) 1989-10-06
FI90254C (fi) 1994-01-10
EP0353291B1 (en) 1993-01-27
JPH02503057A (ja) 1990-09-27
DK494989A (da) 1989-12-07
EP0353291A1 (en) 1990-02-07
FI894472A0 (fi) 1989-09-21
JP2756606B2 (ja) 1998-05-25
WO1989007133A3 (en) 1989-09-08
CA1282361C (en) 1991-04-02

Similar Documents

Publication Publication Date Title
FI894472A (fi) Dynaaminen jatkuvavirtauksinen entsyymireaktori
DK470787D0 (da) Enzymer med aendret aktivitet
FI910185A0 (fi) Staellning foer distribution av flexibelt arkmaterial med automatisk rulloeverfoeringsmekanism.
DK107287D0 (da) Hvirvellagsreaktor
FI900990A0 (fi) Fluid fruktsaft- och aetbara mjukningsmedelsammansaettning med laog fukthalt.
DE68912685D1 (de) Reinigung von Glucosaminoglucan abbauenden Enzymen.
DK633488D0 (da) Reaktor
DK555289D0 (da) Fermenteringsfremgangsmaade
FR2597106B1 (fr) Tripeptide doue d'une activite immunostimulante
DK257189A (da) Hydrodynamisk trykleje
NO176574C (no) Dynamisk kontinuerlig strömmende enzymreaktor
FR2597107B1 (fr) Tripeptide doue d'une activite immunostimulante
IT1197688B (it) Attivita' antiflogistica,analgesica,antipiretica ed antiaggregante piastrinica di 1-metil-5-metilbenzoilpirrol-2-acetamido acetanilidi
ATE85075T1 (de) Enzymreaktor mit dynamischem kontinuierlichem durchfluss.
DK328089A (da) Enzym
KR900003179U (ko) 유체 이음구
DK205488D0 (da) Enzym
KR850006361U (ko) 의 자
BR8800511A (pt) Controlador dinamico do fluxo de gas
KR900003178U (ko) 유체 이음구
DK162289D0 (da) Immobiliserede enzymer
KR890020494U (ko) 담배 파이프
DK124390D0 (da) Prostaglandinderivater med antitrombotisk virkning
KR860007208U (ko) 못자리용 의자
KR890020886U (ko) 동적 장식품

Legal Events

Date Code Title Description
BB Publication of examined application
MM Patent lapsed
MM Patent lapsed

Owner name: MOUNT SINAI SCHOOL OF MEDICINE OF THE